Page last updated: 2024-11-05

xylazine and Bradyarrhythmia

xylazine has been researched along with Bradyarrhythmia in 14 studies

Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.

Research Excerpts

ExcerptRelevanceReference
" In a controlled study, we evaluated the effects of yohimbine, an antagonist of xylazine, on the anesthesia induced by this anesthetic combination in cats."7.67Effect of yohimbine on xylazine-ketamine anesthesia in cats. ( Hsu, WH; Lu, ZX, 1984)
"Two doses of an alpha 2-adrenoreceptor antagonist, idazoxan, were administered to reverse the CNS depressant and bradycardia effects of xylazine in calves."7.67Antagonistic effect of idazoxan on xylazine-induced central nervous system depression and bradycardia in calves. ( Hsu, WH; Kersting, KW; Thompson, JR, 1989)
" In a controlled study, we evaluated the effects of yohimbine, an antagonist of xylazine, on the anesthesia induced by this anesthetic combination in cats."3.67Effect of yohimbine on xylazine-ketamine anesthesia in cats. ( Hsu, WH; Lu, ZX, 1984)
"Two doses of an alpha 2-adrenoreceptor antagonist, idazoxan, were administered to reverse the CNS depressant and bradycardia effects of xylazine in calves."3.67Antagonistic effect of idazoxan on xylazine-induced central nervous system depression and bradycardia in calves. ( Hsu, WH; Kersting, KW; Thompson, JR, 1989)
"Xylazine is an alpha-2 receptor agonist that is not approved for human use but is commonly used in veterinary medicine due to its sedative and muscle-relaxant properties."3.01Pharmacology and toxicology of xylazine: quid novum? ( Berretta, P; Busardò, FP; Kapoor, A; Malaca, S; Pesaresi, M; Pirani, F, 2023)
"Xylazine is an alpha-2-adrenergic agonist used for its sedative and analgesic properties in veterinary medicine."2.82Xylazine poisoning: a systematic review. ( Ball, NS; Covvey, JR; Gionfriddo, MR; Guarascio, AJ; Knable, BM; Montepara, CA; Nemecek, BD; Relich, TA; Smathers, AN; Zimmerman, DE, 2022)
"Xylazine alone has proven harmful to humans and even more when it is combined with drugs of abuse."2.50Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature. ( Chavez-Arias, C; Díaz-Alcalá, JE; Martínez, MA; Ruiz-Colón, K, 2014)
"Xylazine was administered i."1.30Actions of xylazine in young swine. ( Castillo-Olivares, JL; Gómez de Segura, IA; Mascías, A; Santos, M; Steffey, EP; Tendillo, FJ, 1997)
"He subsequently became comatose, hypotensive, bradycardic and acidotic."1.28Accidental self administration of xylazine in a veterinary nurse. ( Roffe, C; Samanta, A; Woods, KL, 1990)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's4 (28.57)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Ball, NS1
Knable, BM1
Relich, TA1
Smathers, AN1
Gionfriddo, MR1
Nemecek, BD1
Montepara, CA1
Guarascio, AJ1
Covvey, JR1
Zimmerman, DE1
Malaca, S1
Pesaresi, M1
Kapoor, A1
Berretta, P1
Busardò, FP1
Pirani, F1
Leconte, CE1
Sethi, R1
Tsukamoto, A1
Niino, N1
Sakamoto, M1
Ohtani, R1
Inomata, T1
Ruiz-Colón, K1
Chavez-Arias, C1
Díaz-Alcalá, JE1
Martínez, MA1
Cruz, FS1
Carregaro, AB1
Machado, M1
Antonow, RR1
Velez, LI1
Shepherd, G1
Mills, LD1
Rivera, W1
Lewis, S1
O'Callaghan, CL1
Toghill, PJ1
Hsu, WH2
Lu, ZX1
Fyffe, JJ1
Gómez de Segura, IA1
Tendillo, FJ1
Mascías, A1
Santos, M1
Castillo-Olivares, JL1
Steffey, EP1
Van Metre, DC1
Samanta, A1
Roffe, C1
Woods, KL1
Thompson, JR1
Kersting, KW1

Reviews

4 reviews available for xylazine and Bradyarrhythmia

ArticleYear
Xylazine poisoning: a systematic review.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:8

    Topics: Adrenergic Agonists; Bradycardia; Humans; Hypnotics and Sedatives; Hypotension; United States; Xylaz

2022
Pharmacology and toxicology of xylazine: quid novum?
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:15

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Bradycardia; Humans; Hypnotics and Sedativ

2023
Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature.
    Forensic science international, 2014, Volume: 240

    Topics: Bradycardia; Chromatography; Drug Contamination; Forensic Toxicology; Humans; Hyperglycemia; Hypnoti

2014
Effects of xylazine on humans: a review.
    Australian veterinary journal, 1994, Volume: 71, Issue:9

    Topics: Bradycardia; Humans; Hypotension; Suicide, Attempted; Xylazine

1994

Trials

1 trial available for xylazine and Bradyarrhythmia

ArticleYear
Sedative and cardiopulmonary effects of buprenorphine and xylazine in horses.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2011, Volume: 75, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Animals; Blood Gas Analysis; Bradycardia;

2011

Other Studies

9 other studies available for xylazine and Bradyarrhythmia

ArticleYear
The Appearance of Xylazine in the United States as a Fentanyl Adulterant.
    The primary care companion for CNS disorders, 2023, Oct-31, Volume: 25, Issue:6

    Topics: Bradycardia; Drug Overdose; Fentanyl; Humans; Naloxone; United States; Xylazine

2023
The validity of anesthetic protocols for the surgical procedure of castration in rats.
    Experimental animals, 2018, Jul-30, Volume: 67, Issue:3

    Topics: Administration, Inhalation; Anesthesia; Anesthetics; Animal Experimentation; Animals; Bradycardia; B

2018
Systemic toxicity after an ocular exposure to xylazine hydrochloride.
    The Journal of emergency medicine, 2006, Volume: 30, Issue:4

    Topics: Accidents, Occupational; Adrenergic alpha-Agonists; Adult; Bradycardia; Consciousness Disorders; Eye

2006
Clinical curio: self medication with xylazine.
    British medical journal (Clinical research ed.), 1983, Nov-05, Volume: 287, Issue:6402

    Topics: Adult; Bradycardia; Female; Humans; Self Medication; Thiazines; Xylazine

1983
Effect of yohimbine on xylazine-ketamine anesthesia in cats.
    Journal of the American Veterinary Medical Association, 1984, Oct-15, Volume: 185, Issue:8

    Topics: Anesthesia; Animals; Bradycardia; Cat Diseases; Cats; Female; Heart Block; Heart Rate; Ketamine; Mal

1984
Actions of xylazine in young swine.
    American journal of veterinary research, 1997, Volume: 58, Issue:1

    Topics: Analgesics; Anesthetics; Animals; Behavior, Animal; Blood Pressure; Bradycardia; Cardiovascular Phys

1997
A case report of the treatment of an overdose of xylazine in a cow.
    The Cornell veterinarian, 1992, Volume: 82, Issue:3

    Topics: Animals; Atropine; Bradycardia; Cattle; Cattle Diseases; Drug Overdose; Female; Fluid Therapy; Heart

1992
Accidental self administration of xylazine in a veterinary nurse.
    Postgraduate medical journal, 1990, Volume: 66, Issue:773

    Topics: Accidents, Occupational; Acidosis; Adult; Bradycardia; Coma; Humans; Hypotension; Male; Nurses, Male

1990
Antagonistic effect of idazoxan on xylazine-induced central nervous system depression and bradycardia in calves.
    American journal of veterinary research, 1989, Volume: 50, Issue:5

    Topics: Animals; Bradycardia; Cattle; Cattle Diseases; Central Nervous System; Dioxanes; Dioxins; Female; He

1989