xylazine has been researched along with Anoxemia in 19 studies
Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings suggest that xylazine exacerbates the life-threatening effects of opioids, proposing worsened brain hypoxia as the mechanism contributing to xylazine-positive opioid-overdose deaths." | 8.31 | Xylazine effects on opioid-induced brain hypoxia. ( Choi, S; Irwin, MR; Kiyatkin, EA, 2023) |
| "These findings suggest that xylazine exacerbates the life-threatening effects of opioids, proposing worsened brain hypoxia as the mechanism contributing to xylazine-positive opioid-overdose deaths." | 4.31 | Xylazine effects on opioid-induced brain hypoxia. ( Choi, S; Irwin, MR; Kiyatkin, EA, 2023) |
| "Ketamine is often used in combination with tranquilizers to produce surgical anesthesia in rabbits." | 3.68 | Ketamine/xylazine/butorphanol: a new anesthetic combination for rabbits. ( Avison, DL; Corning, BF; Lipman, NS; Marini, RP, 1992) |
| "ketamine dosages were evaluated: 0." | 2.72 | Effects of ketamine on carfentanil and xylazine immobilization of white-tailed deer (Odocoileus virginianus). ( Miller, KV; Osborn, DA; Ramsay, EC; Schumacher, J; Storms, TN, 2006) |
| "The purpose of this study was to examine the effects of a clinically relevant opioid on the production of augmented breaths (ABs) in unanesthetized animals breathing normal room air, using a dosage which does not depress breathing." | 1.37 | The "other" respiratory effect of opioids: suppression of spontaneous augmented ("sigh") breaths. ( Azubike, E; Bell, HJ; Haouzi, P, 2011) |
| "Anesthetized animals showed profound hypoxemia with mild hypercapnia, tachycardia, hypertension, and acidosis prior to naloxone administration." | 1.31 | Use of naloxone to reverse carfentanil citrate-induced hypoxemia and cardiopulmonary depression in Rocky Mountain wapiti (Cervus elaphus nelsoni). ( Gaynor, JS; Larsen, RS; Moresco, A; Sleeman, JM; Wild, MA, 2001) |
| "All wapiti exhibited mild to marked hypoxemia (PaO2 = 43 +/- 11." | 1.31 | Treatment of hypoxemia during xylazine-tiletamine-zolazepam immobilization of wapiti. ( Caulkett, NA; Read, MR; Shury, TK; Symington, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| David, EM | 1 |
| Pacharinsak, C | 1 |
| Jampachaisri, K | 1 |
| Hagan, L | 1 |
| Marx, JO | 1 |
| Choi, S | 1 |
| Irwin, MR | 1 |
| Kiyatkin, EA | 1 |
| Cardoso, CG | 1 |
| Ayer, IM | 1 |
| Jorge, AT | 1 |
| Honsho, CS | 1 |
| Mattos-Junior, E | 1 |
| Singh, PM | 1 |
| Reid, K | 1 |
| Gaddam, R | 1 |
| Bhatia, M | 1 |
| Smith, S | 1 |
| Jacob, A | 1 |
| Chambers, P | 1 |
| Hopster, K | 1 |
| Wittenberg-Voges, L | 1 |
| Geburek, F | 1 |
| Hopster-Iversen, C | 1 |
| Kästner, SBR | 1 |
| Lian, M | 1 |
| Björck, S | 1 |
| Arnemo, JM | 1 |
| Esteruelas, NF | 1 |
| Angel, M | 1 |
| Minsaas, SC | 1 |
| Jones, KL | 1 |
| L Evans, A | 1 |
| Bell, HJ | 1 |
| Azubike, E | 1 |
| Haouzi, P | 1 |
| Moresco, A | 1 |
| Larsen, RS | 1 |
| Sleeman, JM | 1 |
| Wild, MA | 1 |
| Gaynor, JS | 1 |
| Oku, K | 1 |
| Yamanaka, T | 1 |
| Ashihara, N | 1 |
| Kawasaki, K | 1 |
| Mizuno, Y | 1 |
| Fujinaga, T | 1 |
| Storms, TN | 1 |
| Schumacher, J | 1 |
| Osborn, DA | 1 |
| Miller, KV | 1 |
| Ramsay, EC | 1 |
| Ko, JC | 1 |
| Payton, M | 1 |
| Weil, AB | 1 |
| Kitao, T | 1 |
| Haydon, T | 1 |
| Celly, CS | 1 |
| McDonell, WN | 1 |
| Young, SS | 1 |
| Black, WD | 1 |
| Jones, JG | 1 |
| Caulkett, NA | 2 |
| Cribb, PH | 1 |
| Haigh, JC | 1 |
| Read, MR | 1 |
| Symington, A | 1 |
| Shury, TK | 1 |
| Marini, RP | 1 |
| Avison, DL | 1 |
| Corning, BF | 1 |
| Lipman, NS | 1 |
| Raptopoulos, D | 1 |
| Nolan, AM | 1 |
| Callingham, BA | 1 |
| Evans, RJ | 1 |
| Bowman, A | 1 |
| McGrath, JC | 1 |
4 trials available for xylazine and Anoxemia
| Article | Year |
|---|---|
Effect of choline chloride premedication on xylazine-induced hypoxaemia in sheep.
Topics: Analgesics; Animals; Blood Gas Analysis; Choline; Female; Hypoxia; Mice; Preanesthetic Medication; R | 2017 |
Clinical observations during induction and recovery of xylazine-midazolam- propofol anesthesia in horses.
Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Blood Pressu | 2003 |
Effects of ketamine on carfentanil and xylazine immobilization of white-tailed deer (Odocoileus virginianus).
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Animals, Wild; Bl | 2006 |
Comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-butorphanol and tiletamine-zolazepam-butorphanol-medetomidine in dogs.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Anesthet | 2007 |
15 other studies available for xylazine and Anoxemia
| Article | Year |
|---|---|
Use of Ketamine or Xylazine to Provide Balanced Anesthesia with Isoflurane in C57BL/6J Mice.
Topics: Anesthetics, Inhalation; Animals; Balanced Anesthesia; Crystalloid Solutions; Female; Hypovolemia; H | 2022 |
Xylazine effects on opioid-induced brain hypoxia.
Topics: Analgesics, Opioid; Animals; Drug Overdose; Fentanyl; Heroin; Humans; Hypothermia; Hypoxia; Hypoxia, | 2023 |
A comparative study of the cardiopulmonary and sedative effects of a single intramuscular dose of ketamine anesthetic combinations in rabbits.
Topics: Acepromazine; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Arterial Pressure; Cross | 2020 |
Effects of controlled hypoxemia or hypovolemia on global and intestinal oxygenation and perfusion in isoflurane anesthetized horses receiving an alpha-2-agonist infusion.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dexmedetomidine; Female; Heart Rate; Horse | 2017 |
Severe Hypoxemia in Muskoxen ( Ovibos moschatus ) Immobilized with Etorphine and Xylazine Corrected with Supplemental Nasal Oxygen.
Topics: Animals; Etorphine; Hypnotics and Sedatives; Hypoxia; Immobilization; Oximetry; Oxygen; Ruminants; S | 2017 |
The "other" respiratory effect of opioids: suppression of spontaneous augmented ("sigh") breaths.
Topics: Analgesics, Opioid; Animals; Hypnotics and Sedatives; Hypoxia; Ketamine; Male; Morphine; Naloxone; R | 2011 |
Use of naloxone to reverse carfentanil citrate-induced hypoxemia and cardiopulmonary depression in Rocky Mountain wapiti (Cervus elaphus nelsoni).
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Blood Gas Analysis; Cross-Over Studies; Deer | 2001 |
The comparative hypoxaemic effect of four alpha 2 adrenoceptor agonists (xylazine, romifidine, detomidine and medetomidine) in sheep.
Topics: Adrenergic alpha-Agonists; Analgesics; Anesthetics; Animals; Female; Hemodynamics; Hypoxia; Imidazol | 1997 |
Alpha-2 receptor agonists and a species-specific mechanism of hypoxaemia.
Topics: Adrenergic alpha-Agonists; Animals; Hypoxia; Sheep; Sheep Diseases; Species Specificity; Xylazine | 1999 |
Comparative cardiopulmonary effects of carfentanil-xylazine and medetomidine-ketamine used for immobilization of mule deer and mule deer/white-tailed deer hybrids.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Anesthetics, Dissociative; Animal Welfare; Animals; A | 2000 |
Treatment of hypoxemia during xylazine-tiletamine-zolazepam immobilization of wapiti.
Topics: Adrenergic alpha-Agonists; Anesthetics, Dissociative; Animals; Animals, Wild; Anti-Anxiety Agents; B | 2001 |
Ketamine/xylazine/butorphanol: a new anesthetic combination for rabbits.
Topics: Anesthesia; Animals; Blood Pressure; Butorphanol; Dose-Response Relationship, Drug; Drug Combination | 1992 |
The role of hypoxia in the hyperglycaemic effect of xylazine in sheep.
Topics: Animals; Blood Gas Analysis; Hyperglycemia; Hypoxia; Male; Sheep; Sheep Diseases; Thiazines; Xylazin | 1990 |
Effects of aspirin on xylazine-induced hypoxaemia in sheep.
Topics: Animals; Aspirin; Female; Hypoxia; Injections, Intravenous; Male; Oxygen; Platelet Aggregation; Plat | 1990 |
The effect of hypoxia on neuroeffector transmission in the bovine retractor penis and rat anococcygeus muscles.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Alprostadil; Animals; Cattle; Electric Stimulation; Guanethidine; G | 1985 |