xylazine has been researched along with Allodynia in 4 studies
Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Xylazine is an alpha(2)-adrenoceptor agonist extensively used in veterinary and animal experimentation." | 1.35 | Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine. ( de Castro Perez, A; de Francischi, JN; Gama Duarte, ID; Romero, TR, 2009) |
| "Xylazine was administered locally into the right hind paw (25, 50 and 100 microg) and either NO synthase inhibitor L-NOarg (12, 18 and 24 microg/paw), soluble guanylyl cyclase inhibitor ODQ (25, 50 and 100 microg/paw) or cGMP-phosphodiesterase inhibitor zaprinast (50 microg/paw) were previously administered to the right hind paw of Wistar rats." | 1.35 | alpha(2)-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the L-arginine/nitric oxide/cyclic GMP pathway in rat. ( Duarte, ID; Romero, TR, 2009) |
| "Xylazine is an alpha(2)-adrenergic agonist extensively used in veterinary medicine and animal experimentation for producing antinociception, sedation, and muscle relaxation." | 1.35 | Involvement of ATP-sensitive K(+) channels in the peripheral antinociceptive effect induced by the alpha(2)-adrenoceptor agonist xylazine. ( Duarte, ID; Romero, TR, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Romero, TRL | 1 |
| Miranda E Castor, MG | 1 |
| Parrella, C | 1 |
| Piscitelli, F | 1 |
| Di Marzo, V | 1 |
| Duarte, IDG | 1 |
| Romero, TR | 3 |
| de Castro Perez, A | 1 |
| de Francischi, JN | 1 |
| Gama Duarte, ID | 1 |
| Duarte, ID | 2 |
4 other studies available for xylazine and Allodynia
| Article | Year |
|---|---|
α
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Arachidonic Acids; Chromatography, Liquid | 2020 |
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; | 2009 |
alpha(2)-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the L-arginine/nitric oxide/cyclic GMP pathway in rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relat | 2009 |
Involvement of ATP-sensitive K(+) channels in the peripheral antinociceptive effect induced by the alpha(2)-adrenoceptor agonist xylazine.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Dinoprostone; Dose-Response Relationship, Drug; Drug | 2009 |