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xylazine and Allodynia

xylazine has been researched along with Allodynia in 4 studies

Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.

Research Excerpts

ExcerptRelevanceReference
"Xylazine is an alpha(2)-adrenoceptor agonist extensively used in veterinary and animal experimentation."1.35Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine. ( de Castro Perez, A; de Francischi, JN; Gama Duarte, ID; Romero, TR, 2009)
"Xylazine was administered locally into the right hind paw (25, 50 and 100 microg) and either NO synthase inhibitor L-NOarg (12, 18 and 24 microg/paw), soluble guanylyl cyclase inhibitor ODQ (25, 50 and 100 microg/paw) or cGMP-phosphodiesterase inhibitor zaprinast (50 microg/paw) were previously administered to the right hind paw of Wistar rats."1.35alpha(2)-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the L-arginine/nitric oxide/cyclic GMP pathway in rat. ( Duarte, ID; Romero, TR, 2009)
"Xylazine is an alpha(2)-adrenergic agonist extensively used in veterinary medicine and animal experimentation for producing antinociception, sedation, and muscle relaxation."1.35Involvement of ATP-sensitive K(+) channels in the peripheral antinociceptive effect induced by the alpha(2)-adrenoceptor agonist xylazine. ( Duarte, ID; Romero, TR, 2009)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Romero, TRL1
Miranda E Castor, MG1
Parrella, C1
Piscitelli, F1
Di Marzo, V1
Duarte, IDG1
Romero, TR3
de Castro Perez, A1
de Francischi, JN1
Gama Duarte, ID1
Duarte, ID2

Other Studies

4 other studies available for xylazine and Allodynia

ArticleYear
α
    Pharmacological reports : PR, 2020, Volume: 72, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Arachidonic Acids; Chromatography, Liquid

2020
Probable involvement of alpha(2C)-adrenoceptor subtype and endogenous opioid peptides in the peripheral antinociceptive effect induced by xylazine.
    European journal of pharmacology, 2009, Apr-17, Volume: 608, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals;

2009
alpha(2)-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the L-arginine/nitric oxide/cyclic GMP pathway in rat.
    European journal of pharmacology, 2009, Jun-24, Volume: 613, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relat

2009
Involvement of ATP-sensitive K(+) channels in the peripheral antinociceptive effect induced by the alpha(2)-adrenoceptor agonist xylazine.
    Journal of pharmacological sciences, 2009, Volume: 111, Issue:4

    Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Dinoprostone; Dose-Response Relationship, Drug; Drug

2009