xylazine has been researched along with Acute Hypercapnic Respiratory Failure in 6 studies
Xylazine: An adrenergic alpha-2 agonist used as a sedative, analgesic and centrally acting muscle relaxant in VETERINARY MEDICINE.
xylazine : A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These findings suggest that xylazine exacerbates the life-threatening effects of opioids, proposing worsened brain hypoxia as the mechanism contributing to xylazine-positive opioid-overdose deaths." | 8.31 | Xylazine effects on opioid-induced brain hypoxia. ( Choi, S; Irwin, MR; Kiyatkin, EA, 2023) |
| " Since sedation of animals is necessary to avoid artifacts, a mixture of ketamine and xylazine is frequently used for anesthesia." | 7.72 | Ketamine/xylazine anesthesia for radiologic imaging of neurologically impaired rats: dose response, respiratory depression, and management of complications. ( Dittmar, MS; Fehm, NP; Horn, M; Vatankhah, B, 2004) |
| "These findings suggest that xylazine exacerbates the life-threatening effects of opioids, proposing worsened brain hypoxia as the mechanism contributing to xylazine-positive opioid-overdose deaths." | 4.31 | Xylazine effects on opioid-induced brain hypoxia. ( Choi, S; Irwin, MR; Kiyatkin, EA, 2023) |
| " Since sedation of animals is necessary to avoid artifacts, a mixture of ketamine and xylazine is frequently used for anesthesia." | 3.72 | Ketamine/xylazine anesthesia for radiologic imaging of neurologically impaired rats: dose response, respiratory depression, and management of complications. ( Dittmar, MS; Fehm, NP; Horn, M; Vatankhah, B, 2004) |
| "Xylazine alone has proven harmful to humans and even more when it is combined with drugs of abuse." | 2.50 | Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature. ( Chavez-Arias, C; Díaz-Alcalá, JE; Martínez, MA; Ruiz-Colón, K, 2014) |
| "The purpose of this study was to examine the effects of a clinically relevant opioid on the production of augmented breaths (ABs) in unanesthetized animals breathing normal room air, using a dosage which does not depress breathing." | 1.37 | The "other" respiratory effect of opioids: suppression of spontaneous augmented ("sigh") breaths. ( Azubike, E; Bell, HJ; Haouzi, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Deutsch, SA | 1 |
| De Jong, AR | 1 |
| Choi, S | 1 |
| Irwin, MR | 1 |
| Kiyatkin, EA | 1 |
| Tsukamoto, A | 1 |
| Konishi, Y | 1 |
| Kawakami, T | 1 |
| Koibuchi, C | 1 |
| Sato, R | 1 |
| Kanai, E | 1 |
| Inomata, T | 1 |
| Ruiz-Colón, K | 1 |
| Chavez-Arias, C | 1 |
| Díaz-Alcalá, JE | 1 |
| Martínez, MA | 1 |
| Bell, HJ | 1 |
| Azubike, E | 1 |
| Haouzi, P | 1 |
| Dittmar, MS | 1 |
| Fehm, NP | 1 |
| Vatankhah, B | 1 |
| Horn, M | 1 |
1 review available for xylazine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
Xylazine intoxication in humans and its importance as an emerging adulterant in abused drugs: A comprehensive review of the literature.
Topics: Bradycardia; Chromatography; Drug Contamination; Forensic Toxicology; Humans; Hyperglycemia; Hypnoti | 2014 |
5 other studies available for xylazine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
Xylazine Complicating Opioid Ingestions in Young Children.
Topics: Adult; Analgesics, Opioid; Child; Child, Preschool; Drug Overdose; Humans; Naloxone; Respiratory Ins | 2023 |
Xylazine effects on opioid-induced brain hypoxia.
Topics: Analgesics, Opioid; Animals; Drug Overdose; Fentanyl; Heroin; Humans; Hypothermia; Hypoxia; Hypoxia, | 2023 |
Pharmacological properties of various anesthetic protocols in 10-day-old neonatal rats.
Topics: Anesthesia; Anesthetics, Combined; Animals; Animals, Newborn; Butorphanol; Dose-Response Relationshi | 2017 |
The "other" respiratory effect of opioids: suppression of spontaneous augmented ("sigh") breaths.
Topics: Analgesics, Opioid; Animals; Hypnotics and Sedatives; Hypoxia; Ketamine; Male; Morphine; Naloxone; R | 2011 |
Ketamine/xylazine anesthesia for radiologic imaging of neurologically impaired rats: dose response, respiratory depression, and management of complications.
Topics: Anesthesia; Anesthetics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Infarcti | 2004 |