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xylamine and Pheochromocytoma

xylamine has been researched along with Pheochromocytoma in 3 studies

xylamine: irreversibly inhibits norepinephrine accumulation by rabbit aortic rings in vitro; UD & journal source given agree on structure of cpd; Negwer calls it the bis(2-chloroethyl) cpd

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"PC12 pheochromocytoma cells take up 3,4-dihydroxyphenylethylamine (dopamine) and norepinephrine by a Na+-dependent, cocaine-sensitive system."7.67Characterization of xylamine binding to proteins of PC12 pheochromocytoma cells. ( Cho, AK; Howard, BD; Koide, M, 1986)
"The protein properties of the neuronal sodium-dependent noradrenaline (NA) transporter of PC12 (rat pheochromocytoma) cells and of bovine adreno-medullary cells were studied by means of binding of 3H-desipramine (3H-DMI)."3.68Biochemical characterization and purification of the neuronal sodium-dependent noradrenaline transporter. ( Blum, B; Bönisch, H; Martiny-Baron, G; Michael-Hepp, J, 1990)
"PC12 pheochromocytoma cells take up 3,4-dihydroxyphenylethylamine (dopamine) and norepinephrine by a Na+-dependent, cocaine-sensitive system."3.67Characterization of xylamine binding to proteins of PC12 pheochromocytoma cells. ( Cho, AK; Howard, BD; Koide, M, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bönisch, H1
Martiny-Baron, G1
Blum, B1
Michael-Hepp, J1
Bitler, CM1
Zhang, MB1
Howard, BD2
Koide, M1
Cho, AK1

Other Studies

3 other studies available for xylamine and Pheochromocytoma

ArticleYear
Biochemical characterization and purification of the neuronal sodium-dependent noradrenaline transporter.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Affinity Labels; Animals; Carrier Proteins; Cattle; Cell M

1990
PC12 variants deficient in catecholamine transport.
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenal Gland Neoplasms; Animals; Biological Transport

1986
Characterization of xylamine binding to proteins of PC12 pheochromocytoma cells.
    Journal of neurochemistry, 1986, Volume: 47, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Benztropine; Binding, Competitive; Biological Transport; Carrier P

1986