Page last updated: 2024-10-21

xanthine and Tumor Lysis Syndrome

xanthine has been researched along with Tumor Lysis Syndrome in 4 studies

7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.

Tumor Lysis Syndrome: A syndrome resulting from cytotoxic therapy, occurring generally in aggressive, rapidly proliferating lymphoproliferative disorders. It is characterized by combinations of hyperuricemia, lactic acidosis, hyperkalemia, hyperphosphatemia and hypocalcemia.

Research Excerpts

ExcerptRelevanceReference
" We experienced three cases of urine xanthine crystals during TLS in patients with hematologic malignancies who received prophylactic febuxostat."8.12Urine Xanthine Crystals in Hematologic Malignancies with Tumor Lysis Syndrome. ( Ashizawa, M; Fujiwara, SI; Hatano, K; Hayatsu, K; Ikeda, T; Ito, S; Kanda, Y; Kawaguchi, S; Matsuoka, S; Minakata, D; Morita, K; Murahashi, R; Nagayama, T; Nakano, H; Nakashima, H; Ohmine, K; Sato, K; Sekiguchi, K; Toda, Y; Umino, K; Yamamoto, C; Yamasaki, R; Yoshizawa, T, 2022)
"Tumor lysis syndrome (TLS) is a life-threatening oncological emergency, and control of serum uric acid level (S-UA) is most important."7.80Febuxostat for management of tumor lysis syndrome including its effects on levels of purine metabolites in patients with hematological malignancies - a single institution's, pharmacokinetic and pilot prospective study. ( Iwasaki, H; Kishi, S; Matsuda, Y; Nakamura, T; Ookura, M; Tai, K; Takai, M; Ueda, T; Yamauchi, T; Yoshida, A, 2014)
" We experienced three cases of urine xanthine crystals during TLS in patients with hematologic malignancies who received prophylactic febuxostat."4.12Urine Xanthine Crystals in Hematologic Malignancies with Tumor Lysis Syndrome. ( Ashizawa, M; Fujiwara, SI; Hatano, K; Hayatsu, K; Ikeda, T; Ito, S; Kanda, Y; Kawaguchi, S; Matsuoka, S; Minakata, D; Morita, K; Murahashi, R; Nagayama, T; Nakano, H; Nakashima, H; Ohmine, K; Sato, K; Sekiguchi, K; Toda, Y; Umino, K; Yamamoto, C; Yamasaki, R; Yoshizawa, T, 2022)
"Tumor lysis syndrome (TLS) is a life-threatening oncological emergency, and control of serum uric acid level (S-UA) is most important."3.80Febuxostat for management of tumor lysis syndrome including its effects on levels of purine metabolites in patients with hematological malignancies - a single institution's, pharmacokinetic and pilot prospective study. ( Iwasaki, H; Kishi, S; Matsuda, Y; Nakamura, T; Ookura, M; Tai, K; Takai, M; Ueda, T; Yamauchi, T; Yoshida, A, 2014)
" Allopurinal dosage should be reduced or discontinued if xanthine nephropathy is suspected."1.34Acute renal failure from xanthine nephropathy during management of acute leukemia. ( Bakdash, S; Ellis, D; Krishnamurti, L; LaRosa, C; McMullen, L; Moritz, ML; Wu, HY, 2007)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Ito, S1
Fujiwara, SI1
Yoshizawa, T1
Hayatsu, K1
Sekiguchi, K1
Murahashi, R1
Nakashima, H1
Matsuoka, S1
Ikeda, T1
Toda, Y1
Kawaguchi, S1
Nagayama, T1
Umino, K1
Minakata, D1
Nakano, H1
Morita, K1
Yamasaki, R1
Ashizawa, M1
Yamamoto, C1
Hatano, K1
Sato, K1
Ohmine, K1
Kanda, Y1
Takai, M1
Yamauchi, T1
Ookura, M1
Matsuda, Y1
Tai, K1
Kishi, S1
Yoshida, A1
Iwasaki, H1
Nakamura, T1
Ueda, T1
Mathisen, MS1
LaRosa, C1
McMullen, L1
Bakdash, S1
Ellis, D1
Krishnamurti, L1
Wu, HY1
Moritz, ML1

Other Studies

4 other studies available for xanthine and Tumor Lysis Syndrome

ArticleYear
Urine Xanthine Crystals in Hematologic Malignancies with Tumor Lysis Syndrome.
    Internal medicine (Tokyo, Japan), 2022, Nov-01, Volume: 61, Issue:21

    Topics: Allopurinol; Hematologic Neoplasms; Humans; Microscopy; Neoplasms; Nephrolithiasis; Tumor Lysis Synd

2022
Febuxostat for management of tumor lysis syndrome including its effects on levels of purine metabolites in patients with hematological malignancies - a single institution's, pharmacokinetic and pilot prospective study.
    Anticancer research, 2014, Volume: 34, Issue:12

    Topics: Aged; Allopurinol; Antineoplastic Agents; Creatinine; Enzyme Inhibitors; Febuxostat; Female; Glomeru

2014
The tumor lysis syndrome.
    The New England journal of medicine, 2011, 08-11, Volume: 365, Issue:6

    Topics: Allopurinol; Drug Costs; Humans; Hypoxanthine; Kidney Diseases; Tumor Lysis Syndrome; Urate Oxidase;

2011
Acute renal failure from xanthine nephropathy during management of acute leukemia.
    Pediatric nephrology (Berlin, Germany), 2007, Volume: 22, Issue:1

    Topics: Acute Kidney Injury; Allopurinol; Child; Enzyme Inhibitors; Female; Humans; Nephrolithiasis; Precurs

2007