xanthine has been researched along with Pregnancy in 36 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to evaluate the influence of clinical and anthropometric parameters on UA and xanthine (X) levels during pregnancy and postpartum in women with physiological pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM), and to evaluate their impact on adverse perinatal outcomes." | 7.88 | Uric Acid and Xanthine Levels in Pregnancy Complicated by Gestational Diabetes Mellitus-The Effect on Adverse Pregnancy Outcomes. ( Bartakova, V; Chalasova, K; Kankova, K; Pacal, L; Pleskacova, A; Tomandl, J, 2018) |
| "The purpose of this study was to investigate whether ischemia and subsequent reperfusion would affect xanthine oxidase activity in fetal rat brain capillaries." | 7.70 | Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries. ( Ikenoue, N; Izumiya, C; Okatani, Y; Wakatsuki, A, 1999) |
| " The findings of raised levels of uric acid in plasma and urine at presentation in the third trimester of pregnancy, and the subsequent fall to almost undetectable levels 6 weeks post-partum, is regarded as evidence of the extent of fetal uric acid production and clearance by the maternal circulation." | 7.67 | Pregnancy in xanthinuria: demonstration of fetal uric acid production? ( Buckley, BM; Fisher, RA; Simmonds, HA; Spencer, RE; Stutchbury, JH; Webster, DR; Wooder, M, 1984) |
| " The aim of this study was to evaluate the influence of clinical and anthropometric parameters on UA and xanthine (X) levels during pregnancy and postpartum in women with physiological pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM), and to evaluate their impact on adverse perinatal outcomes." | 3.88 | Uric Acid and Xanthine Levels in Pregnancy Complicated by Gestational Diabetes Mellitus-The Effect on Adverse Pregnancy Outcomes. ( Bartakova, V; Chalasova, K; Kankova, K; Pacal, L; Pleskacova, A; Tomandl, J, 2018) |
| "Our objective was to determine whether two methylxanthines, pentoxifylline (PTX) and allopurinol, would have beneficial effects on experimental pregnancy-induced pre-eclampsia- like disease in ewes." | 3.71 | Inhibitory effects of methylxanthines on the pre-eclamptic-like symptoms in ewes. ( Németh, I; Pintér, S; Tálosi, G, 2001) |
| "The purpose of this study was to investigate whether ischemia and subsequent reperfusion would affect xanthine oxidase activity in fetal rat brain capillaries." | 3.70 | Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries. ( Ikenoue, N; Izumiya, C; Okatani, Y; Wakatsuki, A, 1999) |
| " The findings of raised levels of uric acid in plasma and urine at presentation in the third trimester of pregnancy, and the subsequent fall to almost undetectable levels 6 weeks post-partum, is regarded as evidence of the extent of fetal uric acid production and clearance by the maternal circulation." | 3.67 | Pregnancy in xanthinuria: demonstration of fetal uric acid production? ( Buckley, BM; Fisher, RA; Simmonds, HA; Spencer, RE; Stutchbury, JH; Webster, DR; Wooder, M, 1984) |
| "Acute hypoxemia defined by umbilical arterial oxygen pressure was accompanied by elevation of uric acid concentrations (P less than ." | 1.28 | Comparison of cord purine metabolites to maternal and neonatal variables of hypoxia. ( Benoit, R; O'Brien, WF; Porter, KB, 1992) |
| "PTH and IL-1-stimulated bone resorption was inhibited by both natural and recombinant superoxide dismutase, an enzyme that depletes tissues of superoxide anions." | 1.28 | Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. ( Bonewald, L; Boyce, BF; Garrett, IR; Mundy, GR; Oreffo, RO; Poser, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (19.44) | 18.7374 |
| 1990's | 11 (30.56) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 6 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pleskacova, A | 1 |
| Bartakova, V | 1 |
| Chalasova, K | 1 |
| Pacal, L | 1 |
| Kankova, K | 1 |
| Tomandl, J | 1 |
| Safronova, VG | 1 |
| Matveeva, NK | 1 |
| Lomova, NA | 1 |
| Belyaeva, AS | 1 |
| Vanko, LV | 1 |
| Senyavina, NV | 1 |
| Khaustova, SA | 1 |
| Grebennik, TK | 1 |
| Pavlovich, SV | 1 |
| Mills, TA | 1 |
| Wareing, M | 1 |
| Shennan, AH | 1 |
| Poston, L | 1 |
| Baker, PN | 1 |
| Greenwood, SL | 1 |
| Tskitishvili, E | 1 |
| Sharentuya, N | 1 |
| Temma-Asano, K | 1 |
| Mimura, K | 1 |
| Kinugasa-Taniguchi, Y | 1 |
| Kanagawa, T | 1 |
| Fukuda, H | 1 |
| Kimura, T | 1 |
| Tomimatsu, T | 1 |
| Shimoya, K | 1 |
| Chiricozzi, E | 1 |
| Fernandez-Fernandez, S | 1 |
| Nardicchi, V | 1 |
| Almeida, A | 1 |
| Bolaños, JP | 1 |
| Goracci, G | 1 |
| Korenovskiĭ, IuV | 1 |
| El'chaninova, SA | 1 |
| Pustovrh, C | 1 |
| Jawerbaum, A | 1 |
| Sinner, D | 1 |
| White, V | 1 |
| Capobianco, E | 1 |
| González, E | 1 |
| Okudaira, S | 1 |
| Suzuki, S | 1 |
| Fujimoto, Y | 1 |
| Uno, E | 1 |
| Sakuma, S | 1 |
| Bhatia, BD | 1 |
| Goel, A | 1 |
| Guller, S | 2 |
| Ma, Y | 1 |
| Malek, A | 2 |
| Di Santo, S | 2 |
| Schneider, H | 3 |
| Sager, R | 2 |
| Andres, AC | 1 |
| Simmonds, HA | 1 |
| Stutchbury, JH | 1 |
| Webster, DR | 1 |
| Spencer, RE | 1 |
| Fisher, RA | 1 |
| Wooder, M | 1 |
| Buckley, BM | 1 |
| Huu, TP | 1 |
| Marquetty, C | 1 |
| Pasquier, C | 1 |
| Hakim, J | 1 |
| Harkness, RA | 1 |
| Geirsson, RT | 1 |
| McFadyen, IR | 1 |
| Ronquist, G | 3 |
| Wedenberg, K | 1 |
| Waldenström, A | 2 |
| Ericson, A | 1 |
| Ulmsten, U | 3 |
| de Haan, HH | 1 |
| Van Reempts, JL | 1 |
| Vles, JS | 1 |
| de Haan, J | 1 |
| Hasaart, TH | 1 |
| Steingrímsdóttir, T | 2 |
| East, CE | 1 |
| Dunster, KR | 1 |
| Colditz, PB | 1 |
| Nath, CE | 1 |
| Earl, JW | 1 |
| Gizzi, F | 1 |
| Papponetti, M | 1 |
| Palka, GD | 1 |
| Ruffini, I | 1 |
| Di Ilio, C | 1 |
| Odorisio, M | 1 |
| Spoto, G | 1 |
| Wakatsuki, A | 1 |
| Okatani, Y | 1 |
| Izumiya, C | 1 |
| Ikenoue, N | 1 |
| Buhimschi, IA | 1 |
| Kramer, WB | 1 |
| Buhimschi, CS | 1 |
| Thompson, LP | 1 |
| Weiner, CP | 1 |
| Klejewski, A | 1 |
| Szcześniak-Chmielecka, A | 1 |
| Zeromska-Cancellaro, M | 1 |
| Urbaniak, T | 1 |
| Tsuda, A | 1 |
| Ikegami, T | 1 |
| Ogawa, M | 1 |
| Tsubaki, H | 1 |
| Obara, M | 1 |
| Tanaka, T | 1 |
| Urayama, O | 1 |
| Chihara, J | 1 |
| Tálosi, G | 1 |
| Németh, I | 1 |
| Pintér, S | 1 |
| Porter, KB | 1 |
| O'Brien, WF | 1 |
| Benoit, R | 1 |
| Mateos, FA | 1 |
| Puig, JG | 1 |
| Ramos, TH | 1 |
| Jiménez, ML | 1 |
| Romera, NM | 1 |
| González, AG | 1 |
| Kjaergaard, N | 1 |
| Møller-Petersen, JF | 1 |
| Kristiansen, FV | 1 |
| Petersen, PL | 1 |
| Ekelund, S | 1 |
| Skovbo, P | 1 |
| Garrett, IR | 1 |
| Boyce, BF | 1 |
| Oreffo, RO | 1 |
| Bonewald, L | 1 |
| Poser, J | 1 |
| Mundy, GR | 1 |
| Stípek, S | 1 |
| Mĕchurová, A | 1 |
| Novák, L | 1 |
| Trojan, S | 1 |
| Toguzov, RT | 1 |
| Demin, VF | 1 |
| Pimenov, AM | 1 |
| Manzke, H | 1 |
| Andreoli, SP | 1 |
| Baehner, RL | 1 |
| Bergstein, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodelling[NCT05483738] | 30 participants (Anticipated) | Interventional | 2020-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for xanthine and Pregnancy
| Article | Year |
|---|---|
[The biochemical markers of hypoxic perinatal affections of central nervous system in newborns].
Topics: Activins; Biomarkers; Central Nervous System; Female; Fetal Hypoxia; Humans; Hypoxanthine; Infant, N | 2012 |
1 trial available for xanthine and Pregnancy
| Article | Year |
|---|---|
Study of free radicals in neonates born through meconium stained amniotic fluid deliveries.
Topics: Amniotic Fluid; Asphyxia Neonatorum; Female; Free Radicals; Humans; Hypoxanthine; Hypoxia-Ischemia, | 2005 |
34 other studies available for xanthine and Pregnancy
| Article | Year |
|---|---|
Uric Acid and Xanthine Levels in Pregnancy Complicated by Gestational Diabetes Mellitus-The Effect on Adverse Pregnancy Outcomes.
Topics: Adult; Biomarkers; Case-Control Studies; Diabetes, Gestational; Female; Humans; Pregnancy; Pregnancy | 2018 |
Production of active oxygen species by blood phagocytes of pregnant women and their newborns with intrauterine infection.
Topics: Adult; CD11b Antigen; Cesarean Section; Communicable Diseases; Escherichia coli; fas Receptor; Femal | 2013 |
Analysis of purine metabolites in maternal serum for evaluating the risk of gestosis.
Topics: Adult; Biomarkers; Chromatography, Reverse-Phase; Female; Gestational Age; Humans; Hypoxanthine; Inf | 2013 |
Acute and chronic modulation of placental chorionic plate artery reactivity by reactive oxygen species.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Antioxidants; Chorion; Fe | 2009 |
Oxidative stress-induced S100B protein from placenta and amnion affects soluble Endoglin release from endothelial cells.
Topics: Adult; Aldehydes; Amnion; Antigens, CD; Cell Survival; Cells, Cultured; Dinoprost; Endoglin; Endothe | 2010 |
Group IIA secretory phospholipase A2 (GIIA) mediates apoptotic death during NMDA receptor activation in rat primary cortical neurons.
Topics: Animals; Annexin A5; Apoptosis; Calcium; Cells, Cultured; Cerebral Cortex; Dose-Response Relationshi | 2010 |
Metalloproteinase 2 activity and modulation in uterus from neonatal streptozotocin-induced diabetic rats during embryo implantation.
Topics: Animals; Animals, Newborn; Diabetes Mellitus, Experimental; Embryo Implantation; Enzyme Inhibitors; | 2002 |
Influence of spinal hypotension on fetal oxidative status during elective cesarean section in uncomplicated pregnancies.
Topics: Adult; Anesthesia, Spinal; Blood Gas Analysis; Blood Glucose; Carbon Dioxide; Cesarean Section; Fema | 2005 |
Effects of reactive oxygen and nitrogen species on cyclooxygenase-1 and -2 activities.
Topics: Animals; Catalase; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase I | 2004 |
Differential release of plasminogen activator inhibitors (PAIs) during dual perfusion of human placenta: implications in preeclampsia.
Topics: Adult; Female; Humans; Perfusion; Placenta; Plasminogen Activator Inhibitor 1; Plasminogen Activator | 2007 |
Dual in vitro perfusion of an isolated cotyledon as a model to study the implication of changes in the third trimester placenta on preeclampsia.
Topics: Antioxidants; Biomarkers; Cotyledon; Culture Media; Cytokines; Female; Humans; Immunohistochemistry; | 2007 |
Pregnancy in xanthinuria: demonstration of fetal uric acid production?
Topics: Adult; Female; Fetus; Humans; Hypoxanthine; Hypoxanthines; Middle Aged; Pregnancy; Pregnancy Complic | 1984 |
Luminol assay for microdetermination of superoxide dismutase activity: its application to human fetal blood.
Topics: Adult; Erythrocytes; Female; Fetal Blood; Humans; Kinetics; Luminescent Measurements; Luminol; Micro | 1984 |
Concentrations of hypoxanthine, xanthine, uridine and urate in amniotic fluid at caesarean section and the association of raised levels with prenatal risk factors and fetal distress.
Topics: Amniotic Fluid; Cesarean Section; Female; Fetal Distress; Fetal Hypoxia; Humans; Hypertension; Hypox | 1983 |
High adenosine content in human uterine smooth muscle compared with striated skeletal muscle.
Topics: Adenosine; Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Hypoxant | 1993 |
Effects of asphyxia on the fetal lamb brain.
Topics: Animals; Blood Pressure; Brain; Brain Edema; Cerebellum; Cerebrovascular Circulation; Female; Fetal | 1993 |
Energy economy in the pregnant human uterus at term: studies on arteriovenous differences in metabolites of carbohydrate, fat and nucleotides.
Topics: Adult; Arteries; Blood Glucose; Carbohydrates; Energy Metabolism; Fatty Acids, Nonesterified; Female | 1993 |
Fetal oxygen saturation monitoring in labour: an analysis of 118 cases.
Topics: Adolescent; Adult; Apgar Score; Female; Fetal Blood; Fetal Monitoring; Humans; Hydrogen-Ion Concentr | 1997 |
Hypoxanthine and xanthine as markers in early diagnosis of foetal diseases.
Topics: Adult; Amniotic Fluid; Biomarkers; Chromatography, High Pressure Liquid; False Positive Reactions; F | 1998 |
Low myometrial glycogen content compared with rectus muscle in term pregnant women before labor.
Topics: Adenosine; Adult; Cesarean Section; Energy Metabolism; Female; Glucose; Glycogen; Humans; Hypoxanthi | 1999 |
Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries.
Topics: Animals; Arteries; Brain; Capillaries; Constriction; Female; Fetus; Hypoxanthine; Ischemia; Ovary; P | 1999 |
Reduction-oxidation (redox) state regulation of matrix metalloproteinase activity in human fetal membranes.
Topics: Acetylcysteine; Cesarean Section; Culture Media, Conditioned; Electrophoresis, Polyacrylamide Gel; E | 2000 |
Plasma purine turnover metabolites in women with normal pregnancy and pregnancy complicated with induced hypertension as compared to fetal well-being indices.
Topics: Adult; Apgar Score; Blood Pressure; Diastole; Female; Gestational Age; Heart Rate, Fetal; Humans; Hy | 2000 |
Effect of reactive oxygen species on fetal lung maturation.
Topics: Animals; Female; Fetal Organ Maturity; Gestational Age; Lung; Pregnancy; Proteolipids; Pulmonary Sur | 2001 |
Effect of hypoxia, oxidative stress and lipopolysaccharides on the release of prostaglandins and cytokines from human term placental explants.
Topics: Adult; Cell Hypoxia; Chorionic Villi; Culture Techniques; Cyclooxygenase Inhibitors; Cytokines; Drug | 2001 |
Inhibitory effects of methylxanthines on the pre-eclamptic-like symptoms in ewes.
Topics: Albumins; Allopurinol; Animals; Bilirubin; Blood Pressure; Fasting; Female; Heme; Hypertension; Hypo | 2001 |
Comparison of cord purine metabolites to maternal and neonatal variables of hypoxia.
Topics: Asphyxia Neonatorum; Female; Fetal Blood; Fetal Monitoring; Heart Rate, Fetal; Humans; Hydrogen-Ion | 1992 |
Prenatal diagnosis of Lesch-Nyhan syndrome by purine analysis of amniotic fluid and cordocentesis.
Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransfe | 1991 |
Xanthine and hypoxanthine in amniotic fluid during pregnancy.
Topics: Amniocentesis; Amniotic Fluid; Cell Hypoxia; Female; Fetus; Humans; Hypoxanthine; Hypoxanthines; Pre | 1990 |
Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo.
Topics: Animals; Bone Resorption; Cells, Cultured; Chickens; Female; Free Radicals; Interleukin-1; Mice; Mic | 1990 |
Hypoxanthine in diagnosis, prognosis and pathogeny of hypoxic injury.
Topics: Amniotic Fluid; Animals; Biomarkers; Cricetinae; Female; Fetal Blood; Fetal Hypoxia; Guinea Pigs; Hy | 1989 |
Influence of perinatal hypoxia on purine contents in erythrocytes of newborn infants.
Topics: Asphyxia Neonatorum; Erythrocytes; Female; Fetal Blood; Fetal Hypoxia; Humans; Hypoxanthine; Hypoxan | 1989 |
Hypoxia and hypoxanthine concentration during delivery.
Topics: Creatinine; Delivery, Obstetric; Female; Fetal Hypoxia; Humans; Hypoxanthines; Infant, Newborn; Preg | 1988 |
In vitro detection of endothelial cell damage using 2-deoxy-D-3H-glucose: comparison with chromium 51, 3H-leucine, 3H-adenine, and lactate dehydrogenase.
Topics: Adenine; Cell Survival; Chromatography, Paper; Chromium; Complement Activation; Deoxy Sugars; Deoxyg | 1985 |