xanthine has been researched along with Parkinson Disease in 8 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Han, C | 1 |
| Xu, Y | 1 |
| Wu, K | 1 |
| Chen, S | 1 |
| Hu, M | 1 |
| Wang, L | 1 |
| Ye, Y | 1 |
| Ye, F | 1 |
| McFarland, NR | 1 |
| Burdett, T | 1 |
| Desjardins, CA | 1 |
| Frosch, MP | 1 |
| Schwarzschild, MA | 1 |
| LeWitt, P | 1 |
| Schultz, L | 1 |
| Auinger, P | 1 |
| Lu, M | 1 |
| Tai, KK | 1 |
| Truong, DD | 1 |
| Daly, JW | 1 |
| Spencer, JP | 1 |
| Jenner, P | 1 |
| Daniel, SE | 1 |
| Lees, AJ | 1 |
| Marsden, DC | 1 |
| Halliwell, B | 1 |
| Loeffler, DA | 1 |
| Camp, DM | 1 |
| Juneau, PL | 1 |
| Harel, E | 1 |
| LeWitt, PA | 1 |
| Kawachi, M | 1 |
| Kono, N | 1 |
| Kiyokawa, H | 1 |
| Mineo, I | 1 |
| Nakajima, H | 1 |
| Shimizu, T | 1 |
| Yorifuji, S | 1 |
| Kuwajima, M | 1 |
| Tarui, S | 1 |
1 review available for xanthine and Parkinson Disease
| Article | Year |
|---|---|
Caffeine analogs: biomedical impact.
Topics: Alzheimer Disease; Asthma; Biomedical Research; Caffeine; Calcium; Central Nervous System Stimulants | 2007 |
7 other studies available for xanthine and Parkinson Disease
| Article | Year |
|---|---|
Synthesis and Evaluation of Phenylxanthine Derivatives as Potential Dual A2AR Antagonists/MAO-B Inhibitors for Parkinson's Disease.
Topics: Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cell Survival; Humans; Molecular Structure; M | 2017 |
Postmortem brain levels of urate and precursors in Parkinson's disease and related disorders.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Brain; Case-Control Studies; Femal | 2013 |
CSF xanthine, homovanillic acid, and their ratio as biomarkers of Parkinson's disease.
Topics: Adult; Age of Onset; Antiparkinson Agents; Biomarkers; Chromatography, High Pressure Liquid; Female; | 2011 |
Activation of adenosine triphosphate-sensitive potassium channels confers protection against rotenone-induced cell death: therapeutic implications for Parkinson's disease.
Topics: Adenosine Triphosphate; Animals; Cell Death; Dose-Response Relationship, Drug; Electron Transport Co | 2002 |
Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8,11,14-Eicosatrienoic Acid; Aged; Aged, 80 and over; Chromatography | 1998 |
Purine-induced alterations of dopamine metabolism in rat pheochromocytoma PC12 cells.
Topics: Adenine; Adenosine; Animals; Disease Models, Animal; Dopamine; Guanine; Guanosine; Hypoxanthine; Neo | 2000 |
Decreased renal clearance of xanthine and hypoxanthine in a patient with renal hypouricemia: a new defect in renal handling of purines.
Topics: Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; P | 1992 |