xanthine has been researched along with Myocardial Ischemia in 18 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The serum concentrations of hypoxanthine, xanthine, uric acid and allantoin were determined in peripheral blood samples from patients with angina pectoris, cerebral insult and myocardial infarction with thrombolytic therapy and were compared with the concentrations obtained for healthy males and females." | 7.69 | A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases. ( Delvoux, B; Greiling, H; Kock, R; Sigmund, M, 1994) |
| ") is thought to protect against the damaging effects of myocardial ischemia-reperfusion injury, whereas xanthine oxidoreductase (XOR) normally causes damage through the generation of reactive oxygen species." | 3.72 | Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage. ( Ahluwalia, A; Benjamin, N; Bond, R; McLean, P; Uppal, R; Webb, A, 2004) |
| " The serum concentrations of hypoxanthine, xanthine, uric acid and allantoin were determined in peripheral blood samples from patients with angina pectoris, cerebral insult and myocardial infarction with thrombolytic therapy and were compared with the concentrations obtained for healthy males and females." | 3.69 | A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases. ( Delvoux, B; Greiling, H; Kock, R; Sigmund, M, 1994) |
| "Hypoxanthine excretion was significantly elevated in patients compared with healthy controls (84." | 1.30 | Urinary hypoxanthine and xanthine levels in acute coronary syndromes. ( Bayindir, O; Boydak, B; Gülter, C; Habif, S; Mutaf, I; Ozmen, D; Senol, B; Turgan, N, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (66.67) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, MC | 1 |
| Velayutham, M | 1 |
| Komatsu, T | 1 |
| Hille, R | 1 |
| Zweier, JL | 2 |
| Lv, Y | 1 |
| Liu, X | 2 |
| Yan, S | 1 |
| Liang, X | 1 |
| Yang, Y | 1 |
| Dai, W | 1 |
| Zhang, W | 1 |
| Bès, S | 1 |
| Tatou, E | 1 |
| Vandroux, D | 1 |
| Tissier, C | 1 |
| Rochette, L | 1 |
| Athias, P | 1 |
| Webb, A | 1 |
| Bond, R | 1 |
| McLean, P | 1 |
| Uppal, R | 1 |
| Benjamin, N | 1 |
| Ahluwalia, A | 1 |
| Li, H | 1 |
| Cui, H | 1 |
| Baldus, S | 1 |
| Müllerleile, K | 1 |
| Chumley, P | 1 |
| Steven, D | 1 |
| Rudolph, V | 1 |
| Lund, GK | 1 |
| Staude, HJ | 1 |
| Stork, A | 1 |
| Köster, R | 1 |
| Kähler, J | 1 |
| Weiss, C | 1 |
| Münzel, T | 1 |
| Meinertz, T | 1 |
| Freeman, BA | 1 |
| Heitzer, T | 1 |
| Kukreja, RC | 1 |
| Kontos, MC | 1 |
| Loesser, KE | 1 |
| Batra, SK | 1 |
| Qian, YZ | 1 |
| Gbur, CJ | 1 |
| Naseem, SA | 1 |
| Jesse, RL | 1 |
| Hess, ML | 1 |
| Elmoselhi, A | 1 |
| Butcher, A | 1 |
| Samson, SE | 1 |
| Grover, AK | 1 |
| Kock, R | 1 |
| Delvoux, B | 1 |
| Sigmund, M | 1 |
| Greiling, H | 1 |
| Golino, P | 1 |
| Ragni, M | 1 |
| Cirillo, P | 1 |
| Avvedimento, VE | 1 |
| Feliciello, A | 1 |
| Esposito, N | 1 |
| Scognamiglio, A | 1 |
| Trimarco, B | 1 |
| Iaccarino, G | 1 |
| Condorelli, M | 1 |
| Chiariello, M | 1 |
| Ambrosio, G | 1 |
| Schultz, HD | 1 |
| Ustinova, EE | 1 |
| Yeung, PK | 1 |
| Buckley, SJ | 1 |
| Hung, OR | 1 |
| Pollak, PT | 1 |
| Barclay, KD | 1 |
| Feng, JD | 1 |
| Klassen, GA | 1 |
| Smolenski, RT | 2 |
| Jayakumar, J | 1 |
| Seymour, AM | 1 |
| Yacoub, MH | 2 |
| Zych, M | 1 |
| Makarewicz, W | 1 |
| Mei, DA | 1 |
| Nithipatikom, K | 1 |
| Lasley, RD | 1 |
| Gross, GJ | 1 |
| Turgan, N | 1 |
| Boydak, B | 1 |
| Habif, S | 1 |
| Gülter, C | 1 |
| Senol, B | 1 |
| Mutaf, I | 1 |
| Ozmen, D | 1 |
| Bayindir, O | 1 |
| Brunvand, H | 1 |
| Westby, J | 1 |
| Lekven, J | 1 |
| Grong, K | 1 |
| de Groot, MJ | 1 |
| Coumans, WA | 1 |
| van der Vusse, GJ | 1 |
18 other studies available for xanthine and Myocardial Ischemia
| Article | Year |
|---|---|
Measurement and characterization of superoxide generation from xanthine dehydrogenase: a redox-regulated pathway of radical generation in ischemic tissues.
Topics: Animals; Animals, Inbred Strains; Avian Proteins; Biocatalysis; Cattle; Chickens; Dogs; Electron Spi | 2014 |
Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.
Topics: Allantoin; Animals; Biomarkers; Cardiovascular Agents; Chromatography, Liquid; Disease Models, Anima | 2010 |
Physiological and metabolic actions of mycophenolate mofetil on cultured newborn rat cardiomyocytes in normoxia and in simulated ischemia.
Topics: Adenosine; Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; Hypoxanthine; Immunosuppressive | 2004 |
Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage.
Topics: Animals; Cardiotonic Agents; Humans; Hydrogen-Ion Concentration; Male; Myocardial Ischemia; Myocardi | 2004 |
Xanthine oxidase catalyzes anaerobic transformation of organic nitrates to nitric oxide and nitrosothiols: characterization of this mechanism and the link between organic nitrate and guanylyl cyclase activation.
Topics: Anions; Benzaldehydes; Binding Sites; Biotransformation; Catechols; Electrochemistry; Electrodes; El | 2005 |
Inhibition of xanthine oxidase improves myocardial contractility in patients with ischemic cardiomyopathy.
Topics: Aged; Cardiomyopathies; Cardiotonic Agents; Enzyme Inhibitors; Female; Humans; Hypoxanthine; Magneti | 2006 |
Oxidant stress increases heat shock protein 70 mRNA in isolated perfused rat heart.
Topics: Animals; Coronary Circulation; Free Radicals; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; In Vitro | 1994 |
Coronary artery contractility, Na(+)-pump and oxygen radicals.
Topics: Animals; Coronary Vessels; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Muscle Contraction; Mus | 1994 |
A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases.
Topics: Adult; Allantoin; Creatine Kinase; Female; Humans; Hypoxanthine; Hypoxanthines; Isoenzymes; Male; My | 1994 |
Effects of tissue factor induced by oxygen free radicals on coronary flow during reperfusion.
Topics: Animals; Blotting, Northern; Cells, Cultured; Coronary Circulation; Cycloheximide; Endothelium, Vasc | 1996 |
Cardiac vagal afferent stimulation by free radicals during ischaemia and reperfusion.
Topics: Animals; Capsaicin; Chemoreceptor Cells; Coronary Vessels; Heart; Hydrogen Peroxide; Myocardial Isch | 1996 |
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.
Topics: Adenosine; Adult; Cardiovascular Agents; Diltiazem; Female; Guanosine; Humans; Hypoxanthine; Inosine | 1997 |
The effects of nucleotide pool on purine production in the postischemic heart.
Topics: Adenosine; Adenosine Triphosphate; Animals; Hypoxanthine; Inosine; Kinetics; Myocardial Ischemia; My | 1998 |
Different mechanism of myocardial nucleotide breakdown during normothermic and hypothermic ischemia.
Topics: Adenosine; Animals; Heart Arrest, Induced; Hypoxanthine; In Vitro Techniques; Inosine; Myocardial Is | 1998 |
Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.
Topics: Adenine Nucleotides; Adenosine; Animals; Benzopyrans; Dihydropyridines; Dogs; Extracellular Space; H | 1998 |
Urinary hypoxanthine and xanthine levels in acute coronary syndromes.
Topics: Acute Disease; Adult; Aged; Angina, Unstable; Biomarkers; Blood Urea Nitrogen; Creatine; Female; Hum | 1999 |
Myocardial adenine nucleotide depletion within 1 h of acute coronary artery occlusion.
Topics: Adenine Nucleotides; Animals; Cats; Constriction; Coronary Vessels; Energy Metabolism; Hemodynamics; | 1992 |
The nucleotide metabolism in lactate perfused hearts under ischaemic and reperfused conditions.
Topics: Adenosine; Adenosine Triphosphate; Animals; Energy Metabolism; Glucose; Glycogen; Guanosine Triphosp | 1992 |