xanthine has been researched along with Kidney Diseases in 18 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Total hydroperoxides (TH) and advanced oxidation protein products (AOPP) as indices of oxidative stress, xanthine (Xa) and hypoxanthine (Hx) as indices of hypoxia, alpha1-microglobulin and N-acetyl-beta-D-glucosaminidase (NAG) as indices of kidney damage were assayed." | 3.74 | Oxidative kidney damage in preterm newborns during perinatal period. ( Bellieni, CV; Buonocore, G; Cataldi, L; Fanos, V; Longini, M; Mussap, M; Perrone, S; Proietti, F, 2007) |
| " Renal and ischemia/reperfusion injury parameters were studied, as well as malondialdehyde as a parameter for oxidative stress." | 3.71 | Off-pump versus on-pump coronary artery bypass grafting: oxidative stress and renal function. ( Aarts, LP; Driessen, AH; Gerritsen, WB; Haas, FJ; van Boven, WJ, 2001) |
| " Next, we carried out a 7-day simultaneous treatment study by two daily treatments, that is, FYX-051 (6 mg/kg) and citrate (2,000 mg/kg), followed by citrate-alone treatment, under the conditions of selected dosing intervals, the second dose of citrate, and dosing volume." | 1.37 | Establishment of simultaneous treatment model with citrate for preventing nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor, in rats. ( Ashizawa, N; Matsumoto, K; Moto, M; Nagata, O; Shimo, T; Taniguchi, T, 2011) |
| "Pyrazinamide (PZA) was used to study the renal handling of hypoxanthine, xanthine and uric acid in 2 normal subjects and in 4 patients with idiopathic renal hypouricemia; one patient was classified as having a postsecretory reabsorption defect, whereas the others were classified as having a presecretory reabsorption defect." | 1.27 | Renal handling of hypoxanthine and xanthine in normal subjects and in four cases of idiopathic renal hypouricemia. ( Akaoka, I; Fujimori, S; Itoh, H; Kanbayashi, T; Kaneko, K; Miyashita, H; Nakayama, Y; Oyama, H, 1988) |
| "In order to elucidate toxic and protective mechanisms responsible for allopurinol-induced nephrotoxicity in rats, we investigated changes in plasma creatinine concentration, renal lipid peroxidation, and renal activities of xanthine oxidase, superoxide dismutase and catalase, as enzymatic factors in producing and scavenging oxygen radicals." | 1.27 | Possible mechanism responsible for allopurinol-nephrotoxicity: lipid peroxidation and systems of producing- and scavenging oxygen radicals. ( Sudo, J; Suzuki, Y, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Sedda, D | 1 |
| Mackowiak, C | 1 |
| Pailloux, J | 1 |
| Culerier, E | 1 |
| Dudas, A | 1 |
| Rontani, P | 1 |
| Erard, N | 1 |
| Lefevre, A | 1 |
| Mavel, S | 1 |
| Emond, P | 1 |
| Foucher, F | 1 |
| Le Bert, M | 1 |
| Quesniaux, VFJ | 1 |
| Mihatsch, MJ | 1 |
| Ryffel, B | 1 |
| Erard-Garcia, M | 1 |
| Shimo, T | 4 |
| Ashizawa, N | 4 |
| Moto, M | 3 |
| Iwanaga, T | 1 |
| Nagata, O | 4 |
| Matsumoto, K | 2 |
| Taniguchi, T | 1 |
| Oba, K | 1 |
| Mathisen, MS | 1 |
| López-Martí, J | 1 |
| Sola, A | 1 |
| Pi, F | 1 |
| Alfaro, V | 1 |
| Marco, A | 1 |
| Hotter, G | 1 |
| Guan, Y | 1 |
| Wu, T | 1 |
| Ye, J | 1 |
| Nakazawa, T | 1 |
| Perrone, S | 1 |
| Mussap, M | 1 |
| Longini, M | 1 |
| Fanos, V | 1 |
| Bellieni, CV | 1 |
| Proietti, F | 1 |
| Cataldi, L | 1 |
| Buonocore, G | 1 |
| Homma, S | 1 |
| Asano, Y | 1 |
| Gerritsen, WB | 1 |
| van Boven, WJ | 1 |
| Driessen, AH | 1 |
| Haas, FJ | 1 |
| Aarts, LP | 1 |
| Gröbner, W | 1 |
| Walter-Sack, I | 1 |
| Kawachi, M | 2 |
| Kono, N | 2 |
| Kiyokawa, H | 2 |
| Mineo, I | 2 |
| Nakajima, H | 2 |
| Shimizu, T | 2 |
| Yorifuji, S | 2 |
| Kuwajima, M | 2 |
| Tarui, S | 1 |
| Puig, JG | 1 |
| Miranda Carús, ME | 1 |
| Mateos, FA | 1 |
| Luz Picazo, M | 1 |
| López Jiménez, M | 1 |
| Ortíz Vázquez, J | 1 |
| Ono, A | 1 |
| Nishimura, T | 1 |
| Laing, I | 1 |
| Brown, JK | 1 |
| Harkness, RA | 1 |
| Kaneko, K | 1 |
| Fujimori, S | 1 |
| Itoh, H | 1 |
| Nakayama, Y | 1 |
| Oyama, H | 1 |
| Kanbayashi, T | 1 |
| Miyashita, H | 1 |
| Akaoka, I | 1 |
| Suzuki, Y | 1 |
| Sudo, J | 1 |
1 review available for xanthine and Kidney Diseases
| Article | Year |
|---|---|
[Xanthinuria].
Topics: Humans; Kidney Diseases; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase | 1997 |
1 trial available for xanthine and Kidney Diseases
| Article | Year |
|---|---|
Clinical and biochemical assessments of damage due to perinatal asphyxia: a double blind trial of a quantitative method.
Topics: Asphyxia Neonatorum; Child Development; Clinical Trials as Topic; Creatinine; Developmental Disabili | 1988 |
16 other studies available for xanthine and Kidney Diseases
| Article | Year |
|---|---|
Deletion of
Topics: Animals; Kidney Diseases; Mice; Purine-Pyrimidine Metabolism, Inborn Errors; Urolithiasis; Xanthine; | 2021 |
Study on species differences in nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor.
Topics: Administration, Oral; Animals; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kidney Dis | 2011 |
Establishment of simultaneous treatment model with citrate for preventing nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor, in rats.
Topics: Animals; Chelating Agents; Citric Acid; Disease Models, Animal; Enzyme Inhibitors; Kidney Diseases; | 2011 |
Study on toxicological aspects of crystal-mediated nephrotoxicity induced by FYX-051, a xanthine oxidoreductase inhibitor, in rats.
Topics: Animals; Crystallization; Enzyme Inhibitors; Kidney; Kidney Diseases; Male; Nitriles; Organ Size; Py | 2011 |
The tumor lysis syndrome.
Topics: Allopurinol; Drug Costs; Humans; Hypoxanthine; Kidney Diseases; Tumor Lysis Syndrome; Urate Oxidase; | 2011 |
Nucleotides modulate renal ischaemia-reperfusion injury by different effects on nitric oxide and superoxide.
Topics: Adenosine; Animals; Blood Urea Nitrogen; Creatinine; Kidney; Kidney Diseases; Lipid Peroxidation; Ma | 2003 |
Determination of uric acid and p-aminohippuric acid in human saliva and urine using capillary electrophoresis with electrochemical detection: potential application in fast diagnosis of renal disease.
Topics: Ascorbic Acid; Electrochemistry; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Hyp | 2005 |
Simultaneous treatment with citrate prevents nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor, in rats.
Topics: Animals; Citric Acid; Crystallization; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fe | 2005 |
Oxidative kidney damage in preterm newborns during perinatal period.
Topics: Acetylglucosaminidase; Alpha-Globulins; Female; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxia; In | 2007 |
Off-pump versus on-pump coronary artery bypass grafting: oxidative stress and renal function.
Topics: Aged; Cardiopulmonary Bypass; Coronary Artery Bypass; Creatinine; Female; Humans; Hypoxanthine; Kidn | 2001 |
[Hyperuricemia and gout--diagnosis].
Topics: Adenine; Adult; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Female; Go | 2002 |
Decreased renal clearance of xanthine and hypoxanthine in a patient with renal hypouricemia: a new defect in renal handling of purines.
Topics: Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; P | 1992 |
Familial nephropathy and gout: which comes first?
Topics: Adult; Creatinine; Female; Gout; Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Kidney Failur | 1991 |
Renal hypouricemia associated with hyperoxypurinemia due to decreased renal excretion of oxypurines: a new defect in renal purine transport.
Topics: Diet; Humans; Hypoxanthine; Hypoxanthines; Kidney Diseases; Kidney Tubules; Kinetics; Male; Middle A | 1991 |
Renal handling of hypoxanthine and xanthine in normal subjects and in four cases of idiopathic renal hypouricemia.
Topics: Adult; Female; Humans; Hypoxanthine; Hypoxanthines; Kidney; Kidney Diseases; Male; Middle Aged; Pyra | 1988 |
Possible mechanism responsible for allopurinol-nephrotoxicity: lipid peroxidation and systems of producing- and scavenging oxygen radicals.
Topics: Allopurinol; Animals; Catalase; Creatinine; Free Radicals; Hypoxanthine; Hypoxanthines; Kidney Disea | 1987 |