xanthine has been researched along with Ischemia in 23 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to investigate whether ischemia and subsequent reperfusion would affect xanthine oxidase activity in fetal rat brain capillaries." | 7.70 | Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries. ( Ikenoue, N; Izumiya, C; Okatani, Y; Wakatsuki, A, 1999) |
| "This study investigates whether ozone could confer protection from hepatic ischemia reperfusion by modifying the accumulation of adenosine and xanthine during ischemia." | 7.70 | Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion. ( Bartrons, R; Gelpi, E; Leon, OS; Peralta, C; Roselló-Catafau, J; Xaus, C, 2000) |
| "The effect of allopurinol was studied in a normothermic liver ischemia rat model." | 7.68 | 60 min normothermic liver ischemia in rats: allopurinol improves energy status and bile flow during reperfusion. ( Drange, A; Farstad, M; Karwinski, W; Søreide, O; Ulvik, R, 1990) |
| "These studies suggest that tourniquet-induced exsanguination for limb surgery is a significant source for toxic oxygen production in the form of H2O2 and that xanthine oxidase is probably the H2O2-generating enzyme that is formed during the ischemia-reperfusion event." | 5.08 | Tourniquet-induced exsanguination in patients requiring lower limb surgery. An ischemia-reperfusion model of oxidant and antioxidant metabolism. ( Barnes, L; Dries, DJ; Mathru, M; Rooney, MW; Sukhani, R; Tonino, P, 1996) |
| "Preconditioning reduced xanthine accumulation and conversion of XDH to XOD in liver during sustained ischemia." | 3.71 | Ischemic preconditioning: a defense mechanism against the reactive oxygen species generated after hepatic ischemia reperfusion. ( Bulbena, O; Cutrin, JC; Gelpi, E; Peralta, C; Poli, G; Prats, N; Roselló-Catafau, J; Xaus, C, 2002) |
| "The purpose of this study was to investigate whether ischemia and subsequent reperfusion would affect xanthine oxidase activity in fetal rat brain capillaries." | 3.70 | Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries. ( Ikenoue, N; Izumiya, C; Okatani, Y; Wakatsuki, A, 1999) |
| "This study investigates whether ozone could confer protection from hepatic ischemia reperfusion by modifying the accumulation of adenosine and xanthine during ischemia." | 3.70 | Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion. ( Bartrons, R; Gelpi, E; Leon, OS; Peralta, C; Roselló-Catafau, J; Xaus, C, 2000) |
| "Adenosine, produced from the decomposition of adenosine triphosphate, is believed to provide protective effects during ischemia." | 3.69 | Ischemia induces significant changes in purine nucleoside concentration in the retina-choroid in rats. ( Li, B; Moshfeghi, AA; Osinski, J; Park, SS; Rosenbaum, PS; Roth, S; Toledano, AY, 1997) |
| "This study was undertaken to determine whether hepatic ischemia and the subsequent reflow of blood have any effect on the conversion of xanthine dehydrogenase to xanthine oxidase (XO)." | 3.68 | Role of conversion of xanthine dehydrogenase to oxidase in ischemic rat liver cell injury. ( Dohi, K; Kawasaki, T; Marubayashi, S; Yamada, K, 1991) |
| "While studying xanthine-xanthine oxidase system it was found, that a considerable accumulation of xanthine and uric acid occurred whereas xanthine dehydrogenase did not transfer in xanthine oxidase during 2 hours of total rat liver ischemia." | 3.68 | [Is xanthine oxidase a universal source of superoxide radicals in ischemic and reperfusion lesions?]. ( Bilenko, MV; Nagler, LG; Oktiabr'skaia, LA; Rashba, IuE; Vartanian, LS, 1990) |
| "The effect of allopurinol was studied in a normothermic liver ischemia rat model." | 3.68 | 60 min normothermic liver ischemia in rats: allopurinol improves energy status and bile flow during reperfusion. ( Drange, A; Farstad, M; Karwinski, W; Søreide, O; Ulvik, R, 1990) |
| "Xanthine was the only biochemical where an increase appeared to correlate with ischemia duration while energy charge was of no value in indicating injury extent." | 1.29 | Adenine nucleotides of ischemic intestine do not reflect injury. ( Bollinger, RR; Canada, AT; Coleman, LR; Fabian, MA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 15 (65.22) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ngu, LH | 1 |
| Afroze, B | 1 |
| Chen, BC | 1 |
| Affandi, O | 1 |
| Zabedah, MY | 1 |
| Corps, CL | 1 |
| Shires, M | 1 |
| Crellin, D | 1 |
| Smolenski, R | 1 |
| Potts, D | 1 |
| Pratt, J | 1 |
| Lodge, JP | 1 |
| Sola, A | 1 |
| Panés, J | 1 |
| Xaus, C | 4 |
| Hotter, G | 2 |
| Net, M | 1 |
| Valero, R | 1 |
| Almenara, R | 1 |
| Barros, P | 1 |
| Capdevila, L | 1 |
| López-Boado, MA | 1 |
| Ruiz, A | 1 |
| Sánchez-Crivaro, F | 1 |
| Miquel, R | 1 |
| Deulofeu, R | 1 |
| Taurá, P | 1 |
| Manyalich, M | 1 |
| García-Valdecasas, JC | 1 |
| Peschechera, A | 1 |
| Ferrari, LE | 1 |
| Arrigoni-Martelli, E | 1 |
| Hülsmann, WC | 1 |
| Yabe, Y | 2 |
| Ishiguro, N | 2 |
| Shimizu, T | 2 |
| Tamura, Y | 1 |
| Wakabayashi, T | 1 |
| Miura, T | 1 |
| Watanabe, K | 1 |
| Hayashi, M | 1 |
| Senga, S | 1 |
| Miyata, T | 1 |
| Iida, T | 1 |
| Onitsuka, A | 1 |
| Hirose, H | 1 |
| Canada, AT | 1 |
| Coleman, LR | 1 |
| Fabian, MA | 1 |
| Bollinger, RR | 1 |
| Mathru, M | 1 |
| Dries, DJ | 1 |
| Barnes, L | 1 |
| Tonino, P | 1 |
| Sukhani, R | 1 |
| Rooney, MW | 1 |
| Naesh, O | 1 |
| Haljamäe, H | 1 |
| Skielboe, M | 1 |
| Andersen, P | 1 |
| Sztuk, F | 1 |
| Ibsen, A | 1 |
| Hindberg, I | 1 |
| Kawasaki, S | 1 |
| Sasaki, Y | 1 |
| Iwata, H | 1 |
| Roth, S | 1 |
| Rosenbaum, PS | 1 |
| Osinski, J | 1 |
| Park, SS | 1 |
| Toledano, AY | 1 |
| Li, B | 1 |
| Moshfeghi, AA | 1 |
| Cairo, G | 1 |
| Tacchini, L | 1 |
| Recalcati, S | 1 |
| Azzimonti, B | 1 |
| Minotti, G | 1 |
| Bernelli-Zazzera, A | 1 |
| Peralta, C | 3 |
| Closa, D | 1 |
| Gelpí, E | 3 |
| Roselló-Catafau, J | 3 |
| Wakatsuki, A | 1 |
| Okatani, Y | 1 |
| Izumiya, C | 1 |
| Ikenoue, N | 1 |
| Sperlágh, B | 1 |
| Dóda, M | 1 |
| Baranyi, M | 1 |
| Haskó, G | 1 |
| Bartrons, R | 1 |
| Leon, OS | 1 |
| Bulbena, O | 1 |
| Prats, N | 1 |
| Cutrin, JC | 1 |
| Poli, G | 1 |
| Kobayashi, H | 1 |
| Nonami, T | 1 |
| Kurokawa, T | 1 |
| Sugiyama, S | 1 |
| Ozawa, T | 1 |
| Takagi, H | 1 |
| Marubayashi, S | 1 |
| Dohi, K | 1 |
| Yamada, K | 1 |
| Kawasaki, T | 1 |
| Rashba, IuE | 1 |
| Nagler, LG | 1 |
| Vartanian, LS | 1 |
| Oktiabr'skaia, LA | 1 |
| Bilenko, MV | 1 |
| Karwinski, W | 1 |
| Drange, A | 1 |
| Farstad, M | 1 |
| Ulvik, R | 1 |
| Søreide, O | 1 |
| Maessen, JG | 1 |
| van der Vusse, GJ | 1 |
| Vork, M | 1 |
| Coumans, WA | 1 |
| Kootstra, G | 1 |
1 trial available for xanthine and Ischemia
| Article | Year |
|---|---|
Tourniquet-induced exsanguination in patients requiring lower limb surgery. An ischemia-reperfusion model of oxidant and antioxidant metabolism.
Topics: Adult; Antioxidants; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Ischemia; Knee J | 1996 |
22 other studies available for xanthine and Ischemia
| Article | Year |
|---|---|
Molybdenum cofactor deficiency in a Malaysian child.
Topics: Brain Diseases; Child; Coenzymes; Cysteine; Diagnosis, Differential; Humans; Hypoxanthine; Hypoxia; | 2009 |
Influence on energy kinetics and histology of different preservation solutions seen during cold ischemia in the liver.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Energy Metabolism; | 2009 |
Fructose-1,6-biphosphate and nucleoside pool modifications prevent neutrophil accumulation in the reperfused intestine.
Topics: Adenosine; Animals; Free Radicals; Fructosediphosphates; Intestines; Ischemia; Male; Neutrophil Infi | 2003 |
The effect of normothermic recirculation is mediated by ischemic preconditioning in NHBD liver transplantation.
Topics: Adenosine; Animals; Aspartate Aminotransferases; Cyclic AMP; Glutathione Transferase; Graft Survival | 2005 |
Uptake and release of carnitine by vascular endothelium in culture; effects of protons and oxygen free radicals.
Topics: Acidosis; Animals; Carnitine; Cattle; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Female; | 1995 |
Morphologic and metabolic study of the effect of oxygenated perfluorochemical perfusion on amputated rabbit limbs.
Topics: Adenine Nucleotides; Amputation, Surgical; Animals; Blood Substitutes; Capillaries; Endothelium, Vas | 1994 |
[Changes in high energy phosphates and tissue blood flow in ischemia and reperfusion of jaundiced rat liver--effect of intermittent brief ischemia].
Topics: Adenosine Triphosphate; Animals; Cholestasis; Constriction; Ischemia; Liver; Liver Circulation; Male | 1993 |
Adenine nucleotides of ischemic intestine do not reflect injury.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals | 1993 |
Purine metabolite washout and platelet aggregation at reflow after tourniquet ischemia: effect of intravenous regional lidocaine.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Female; Humans; Hypoxanthine; Hypoxanthines; Ischemia; | 1995 |
A perfluorochemical prevents ischemia-reperfusion injury of muscle.
Topics: Adenine Nucleotides; Animals; Cryopreservation; Endothelium, Vascular; Energy Metabolism; Fluorocarb | 1996 |
Ischemia induces significant changes in purine nucleoside concentration in the retina-choroid in rats.
Topics: Adenosine; Animals; Choroid; Chromatography, High Pressure Liquid; Hypoxanthine; Inosine; Ischemia; | 1997 |
Effect of reactive oxygen species on iron regulatory protein activity.
Topics: Acetylcysteine; Animals; Down-Regulation; Ferritins; Iron; Iron-Regulatory Proteins; Iron-Sulfur Pro | 1998 |
Hepatic preconditioning in rats is defined by a balance of adenosine and xanthine.
Topics: Adenosine; Animals; Ischemia; Ischemic Preconditioning; Liver; Male; Nitric Oxide; Rats; Rats, Wista | 1998 |
Effect of ischemia-reperfusion on xanthine oxidase activity in fetal rat brain capillaries.
Topics: Animals; Arteries; Brain; Capillaries; Constriction; Female; Fetus; Hypoxanthine; Ischemia; Ovary; P | 1999 |
Ischemic-like condition releases norepinephrine and purines from different sources in superfused rat spleen strips.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; | 2000 |
Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion.
Topics: Adenosine; Animals; Ischemia; Liver; Male; Ozone; Rats; Rats, Wistar; Reactive Oxygen Species; Reper | 2000 |
Ischemic preconditioning: a defense mechanism against the reactive oxygen species generated after hepatic ischemia reperfusion.
Topics: Animals; Glutathione; Ischemia; Ischemic Preconditioning; Liver; Male; Malondialdehyde; Neutrophils; | 2002 |
Mechanism and prevention of ischemia-reperfusion-induced liver injury in rats.
Topics: Adenine Nucleotides; Animals; Hepatic Veins; Hypoxanthine; Hypoxanthines; Ischemia; Liver Circulatio | 1991 |
Role of conversion of xanthine dehydrogenase to oxidase in ischemic rat liver cell injury.
Topics: Animals; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Ischemia; Lipid Peroxides; Liver; Male; R | 1991 |
[Is xanthine oxidase a universal source of superoxide radicals in ischemic and reperfusion lesions?].
Topics: Animals; Chromatography; Free Radicals; Hypoxanthine; Hypoxanthines; Ischemia; Liver; Rats; Reperfus | 1990 |
60 min normothermic liver ischemia in rats: allopurinol improves energy status and bile flow during reperfusion.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Bile; Body Temperature; Energy Metabolism; Hypoxanthin | 1990 |
Assessment of warm ischemia time in donor kidneys by analysis of purine metabolism.
Topics: Adenine Nucleotides; Animals; Dogs; Female; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Isch | 1987 |