xanthine has been researched along with Injury, Ischemia-Reperfusion in 34 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigates whether ozone could confer protection from hepatic ischemia reperfusion by modifying the accumulation of adenosine and xanthine during ischemia." | 7.70 | Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion. ( Bartrons, R; Gelpi, E; Leon, OS; Peralta, C; Roselló-Catafau, J; Xaus, C, 2000) |
| "The purpose of this study was to evaluate the possible involvement of xanthine and xanthine oxidase in reperfusion injury in a low-flow, reflow model of liver perfusion." | 7.67 | Role of purines and xanthine oxidase in reperfusion injury in perfused rat liver. ( Lemasters, JJ; Thurman, RG; Zhong, Z, 1989) |
| " Renal and ischemia/reperfusion injury parameters were studied, as well as malondialdehyde as a parameter for oxidative stress." | 3.71 | Off-pump versus on-pump coronary artery bypass grafting: oxidative stress and renal function. ( Aarts, LP; Driessen, AH; Gerritsen, WB; Haas, FJ; van Boven, WJ, 2001) |
| "This study investigates whether ozone could confer protection from hepatic ischemia reperfusion by modifying the accumulation of adenosine and xanthine during ischemia." | 3.70 | Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion. ( Bartrons, R; Gelpi, E; Leon, OS; Peralta, C; Roselló-Catafau, J; Xaus, C, 2000) |
| "Allopurinol (ALL) improves energy metabolism in organs subjected to ischemia-reperfusion injury." | 3.68 | Sixty-minute normothermic liver ischemia in rats. Evidence that allopurinol improves liver cell energy metabolism during reperfusion but that timing of drug administration is important. ( Farstad, M; Karwinski, W; Søreide, O; Ulvik, R, 1991) |
| "The role of xanthine oxidase and oxygen free radicals in postischemic reperfusion injury in the rat kidney remains controversial." | 3.68 | Minimal role of xanthine oxidase and oxygen free radicals in rat renal tubular reoxygenation injury. ( Doctor, RB; Mandel, LJ, 1991) |
| "The purpose of this study was to evaluate the possible involvement of xanthine and xanthine oxidase in reperfusion injury in a low-flow, reflow model of liver perfusion." | 3.67 | Role of purines and xanthine oxidase in reperfusion injury in perfused rat liver. ( Lemasters, JJ; Thurman, RG; Zhong, Z, 1989) |
| "Ischemia-reperfusion injury has been associated with intracellular H2O2 and superoxide radical production from accumulated hypoxanthine (HX) and xanthine oxidase (XO)." | 3.67 | Potential role of mitochondrial calcium metabolism during reperfusion injury. ( Mela-Riker, L; Vlessis, AA, 1989) |
| "In addition, it was found that global cerebral ischemia induced a statistically significant decrease of the hippocampal Na(+),K(+)-ATPase activity starting from 1 to 168 h of reperfusion." | 1.32 | Hyperbaric oxygen treatment: the influence on the hippocampal superoxide dismutase and Na+,K+-ATPase activities in global cerebral ischemia-exposed rats. ( Antoncić, I; Filipović, T; Mrsić-Pelcić, J; Pelcić, G; Simonić, A; Vitezić, D; Zupan, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.82) | 18.7374 |
| 1990's | 13 (38.24) | 18.2507 |
| 2000's | 17 (50.00) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Ruan, Z | 1 |
| Liang, J | 1 |
| Du, Y | 1 |
| Lu, Z | 1 |
| Feng, D | 1 |
| Cai, S | 1 |
| Zhang, X | 1 |
| Cai, W | 1 |
| Hu, Z | 1 |
| Corps, CL | 1 |
| Shires, M | 1 |
| Crellin, D | 1 |
| Smolenski, R | 1 |
| Potts, D | 1 |
| Pratt, J | 1 |
| Lodge, JP | 1 |
| Imura, H | 1 |
| Ayres, BE | 1 |
| Suleiman, MS | 1 |
| Genescà, M | 1 |
| Sola, A | 5 |
| Miquel, R | 2 |
| Pi, F | 2 |
| Xaus, C | 4 |
| Alfaro, V | 4 |
| Hotter, G | 5 |
| Panés, J | 1 |
| López-Martí, J | 1 |
| Marco, A | 1 |
| Mrsić-Pelcić, J | 1 |
| Pelcić, G | 1 |
| Vitezić, D | 1 |
| Antoncić, I | 1 |
| Filipović, T | 1 |
| Simonić, A | 1 |
| Zupan, G | 1 |
| De Oca, J | 1 |
| Jaurrieta, E | 1 |
| Ostadal, P | 1 |
| Elmoselhi, AB | 1 |
| Zdobnicka, I | 1 |
| Lukas, A | 1 |
| Elimban, V | 1 |
| Dhalla, NS | 1 |
| Net, M | 1 |
| Valero, R | 1 |
| Almenara, R | 1 |
| Barros, P | 1 |
| Capdevila, L | 1 |
| López-Boado, MA | 1 |
| Ruiz, A | 1 |
| Sánchez-Crivaro, F | 1 |
| Deulofeu, R | 1 |
| Taurá, P | 1 |
| Manyalich, M | 1 |
| García-Valdecasas, JC | 1 |
| Lee, WY | 1 |
| Lee, SM | 1 |
| Domański, L | 2 |
| Safranow, K | 2 |
| Ostrowski, M | 2 |
| Pawlik, A | 2 |
| Olszewska, M | 1 |
| Dutkiewicz, G | 1 |
| Ciechanowski, K | 2 |
| Jakubowska, K | 1 |
| Dziedziejko, V | 1 |
| Chlubek, D | 1 |
| Rozanski, J | 1 |
| Myslak, M | 1 |
| Romanowski, M | 1 |
| Sulikowski, T | 1 |
| Sienko, J | 1 |
| Yabe, Y | 2 |
| Ishiguro, N | 2 |
| Shimizu, T | 2 |
| Tamura, Y | 1 |
| Wakabayashi, T | 1 |
| Miura, T | 1 |
| Tan, S | 1 |
| Radi, R | 1 |
| Gaudier, F | 1 |
| Evans, RA | 1 |
| Rivera, A | 1 |
| Kirk, KA | 1 |
| Parks, DA | 1 |
| Yang, W | 1 |
| de Bono, D | 1 |
| Kawasaki, S | 1 |
| Sasaki, Y | 1 |
| Iwata, H | 1 |
| Marubayashi, S | 1 |
| Dohi, K | 1 |
| Stipek, S | 1 |
| Novak, L | 1 |
| Crkovska, J | 1 |
| Zima, T | 1 |
| Platenik, J | 1 |
| Kinnula, VL | 1 |
| Sarnesto, A | 1 |
| Heikkilä, L | 1 |
| Toivonen, H | 1 |
| Mattila, S | 1 |
| Raivio, KO | 1 |
| Gerritsen, WB | 2 |
| Aarts, LP | 2 |
| Morshuis, WJ | 1 |
| Haas, FJ | 2 |
| Dambrova, M | 1 |
| Baumane, L | 1 |
| Kiuru, A | 1 |
| Kalvinsh, I | 1 |
| Wikberg, JE | 1 |
| Zhang, H | 1 |
| Joseph, J | 1 |
| Vasquez-Vivar, J | 1 |
| Karoui, H | 1 |
| Nsanzumuhire, C | 1 |
| Martásek, P | 1 |
| Tordo, P | 1 |
| Kalyanaraman, B | 1 |
| Peralta, C | 1 |
| Bartrons, R | 1 |
| Leon, OS | 1 |
| Gelpi, E | 1 |
| Roselló-Catafau, J | 1 |
| van Boven, WJ | 1 |
| Driessen, AH | 1 |
| Kobayashi, H | 2 |
| Kurokawa, T | 2 |
| Kitahara, S | 1 |
| Nonami, T | 2 |
| Harada, A | 1 |
| Nakao, A | 1 |
| Sugiyama, S | 2 |
| Ozawa, T | 2 |
| Takagi, H | 2 |
| Salaris, SC | 1 |
| Babbs, CF | 1 |
| Voorhees, WD | 1 |
| Karwinski, W | 1 |
| Farstad, M | 1 |
| Ulvik, R | 1 |
| Søreide, O | 1 |
| Doctor, RB | 1 |
| Mandel, LJ | 1 |
| Zhong, Z | 1 |
| Lemasters, JJ | 2 |
| Thurman, RG | 2 |
| Marzi, I | 1 |
| Zhi, ZN | 1 |
| Zimmermann, FA | 1 |
| Vlessis, AA | 1 |
| Mela-Riker, L | 1 |
2 reviews available for xanthine and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Therapeutic modulation of free radical-mediated reperfusion injury of the liver and its surgical implications.
Topics: Animals; Cell Adhesion Molecules; Free Radicals; Humans; Liver; Liver Transplantation; Macrophage Ac | 1996 |
Xanthine oxidoreductase. Biochemical, biological and pathogenic functions.
Topics: Animals; Humans; Oxidation-Reduction; Reactive Oxygen Species; Reperfusion Injury; Xanthine; Xanthin | 1994 |
32 other studies available for xanthine and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Protective effect of propofol on ischemia-reperfusion injury detected by HPLC-MS/MS targeted metabolic profiling.
Topics: Anesthetics, Intravenous; Cell Hypoxia; Cell Survival; Cells, Cultured; Chromatography, High Pressur | 2018 |
Influence on energy kinetics and histology of different preservation solutions seen during cold ischemia in the liver.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Allopurinol; Animals; Energy Metabolism; | 2009 |
Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Animals; Guinea Pigs; Heart; Hyperkalemia; Hypothermia; | 2002 |
Role of changes in tissular nucleotides on the development of apoptosis during ischemia/reperfusion in rat small bowel.
Topics: Adenosine; Animals; Apoptosis; Caspase 3; Caspases; Cold Temperature; Intestinal Mucosa; Intestine, | 2002 |
Fructose-1,6-biphosphate and nucleoside pool modifications prevent neutrophil accumulation in the reperfused intestine.
Topics: Adenosine; Animals; Free Radicals; Fructosediphosphates; Intestines; Ischemia; Male; Neutrophil Infi | 2003 |
Nucleotides modulate renal ischaemia-reperfusion injury by different effects on nitric oxide and superoxide.
Topics: Adenosine; Animals; Blood Urea Nitrogen; Creatinine; Kidney; Kidney Diseases; Lipid Peroxidation; Ma | 2003 |
Hyperbaric oxygen treatment: the influence on the hippocampal superoxide dismutase and Na+,K+-ATPase activities in global cerebral ischemia-exposed rats.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Hippocampus; Hyperbaric Oxygenation; Rats; Rats, Wi | 2004 |
Protective effects of exogenous fructose-1,6-biphosphate during small bowel transplantation in rats.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Bacterial Translocation; Cryopreservation; | 2004 |
Intestinal ischemic preconditioning: less xanthine accumulation relates with less apoptosis.
Topics: Allopurinol; Animals; Apoptosis; Caspases; Enzyme Inhibitors; Hypoxanthines; Intestinal Mucosa; Inte | 2004 |
Role of oxidative stress in ischemia-reperfusion-induced changes in Na+,K(+)-ATPase isoform expression in rat heart.
Topics: Animals; Antioxidants; Catalase; Hydrogen Peroxide; In Vitro Techniques; Isoenzymes; Male; Myocardiu | 2004 |
The effect of normothermic recirculation is mediated by ischemic preconditioning in NHBD liver transplantation.
Topics: Adenosine; Animals; Aspartate Aminotransferases; Cyclic AMP; Glutathione Transferase; Graft Survival | 2005 |
Synergistic protective effect of ischemic preconditioning and allopurinol on ischemia/reperfusion injury in rat liver.
Topics: Adenosine; Allopurinol; Animals; Glutathione; Ischemic Preconditioning; Liver; Male; Malondialdehyde | 2006 |
Oxypurine and purine nucleoside concentrations in renal vein of allograft are potential markers of energy status of renal tissue.
Topics: Adult; Biomarkers; Cadaver; Female; Humans; Hypoxanthine; Kidney; Kidney Transplantation; Male; Midd | 2007 |
Purine and cytokine concentrations in the renal vein of the allograft during reperfusion.
Topics: Adult; Cadaver; Cytokines; Female; Humans; Interferon-gamma; Interleukin-2; Kidney Transplantation; | 2007 |
Morphologic and metabolic study of the effect of oxygenated perfluorochemical perfusion on amputated rabbit limbs.
Topics: Adenine Nucleotides; Amputation, Surgical; Animals; Blood Substitutes; Capillaries; Endothelium, Vas | 1994 |
Physiologic levels of uric acid inhibit xanthine oxidase in human plasma.
Topics: Adult; Age Factors; Free Radical Scavengers; Humans; Infant, Newborn; Oxidation-Reduction; Reactive | 1993 |
Myoglobin protects against endothelial cell membrane damage associated with hydrogen peroxide or xanthine/xanthine oxidase.
Topics: Adenine; Animals; Aorta; Ascorbic Acid; Cattle; Cells, Cultured; Endothelium, Vascular; Hydrogen Per | 1993 |
A perfluorochemical prevents ischemia-reperfusion injury of muscle.
Topics: Adenine Nucleotides; Animals; Cryopreservation; Endothelium, Vascular; Energy Metabolism; Fluorocarb | 1996 |
Assessment of xanthine oxidase in human lung and lung transplantation.
Topics: Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Free Radicals; Heart-Lung T | 1997 |
Indices of oxidative stress in urine of patients undergoing coronary artery bypass grafting.
Topics: Aged; Aged, 80 and over; Biomarkers; Coronary Artery Bypass; Creatinine; Female; Humans; Hypoxanthin | 1997 |
N-Hydroxyguanidine compound 1-(3,4-dimethoxy- 2-chlorobenzylideneamino)-3-hydroxyguanidine inhibits the xanthine oxidase mediated generation of superoxide radical.
Topics: Allopurinol; Animals; Binding Sites; Catalysis; Cattle; Chromatography, High Pressure Liquid; Electr | 2000 |
Detection of superoxide anion using an isotopically labeled nitrone spin trap: potential biological applications.
Topics: Calmodulin; Citrulline; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Half-Life; Hydroxyl R | 2000 |
Effect of ozone treatment on reactive oxygen species and adenosine production during hepatic ischemia-reperfusion.
Topics: Adenosine; Animals; Ischemia; Liver; Male; Ozone; Rats; Rats, Wistar; Reactive Oxygen Species; Reper | 2000 |
Off-pump versus on-pump coronary artery bypass grafting: oxidative stress and renal function.
Topics: Aged; Cardiopulmonary Bypass; Coronary Artery Bypass; Creatinine; Female; Humans; Hypoxanthine; Kidn | 2001 |
The effects of gamma-glutamylcysteine ethyl ester, a prodrug of glutathione, on ischemia-reperfusion-induced liver injury in rats.
Topics: Adenine Nucleotides; Animals; Dipeptides; Glutathione; Glutathione Disulfide; Hypoxanthine; Hypoxant | 1992 |
Methylene blue as an inhibitor of superoxide generation by xanthine oxidase. A potential new drug for the attenuation of ischemia/reperfusion injury.
Topics: Animals; Antioxidants; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kidney; Lipid Peroxidation; | 1991 |
Sixty-minute normothermic liver ischemia in rats. Evidence that allopurinol improves liver cell energy metabolism during reperfusion but that timing of drug administration is important.
Topics: Adenosine Triphosphate; Allopurinol; Animals; Bile; Drug Administration Schedule; Energy Metabolism; | 1991 |
Mechanism and prevention of ischemia-reperfusion-induced liver injury in rats.
Topics: Adenine Nucleotides; Animals; Hepatic Veins; Hypoxanthine; Hypoxanthines; Ischemia; Liver Circulatio | 1991 |
Minimal role of xanthine oxidase and oxygen free radicals in rat renal tubular reoxygenation injury.
Topics: Adenine Nucleotides; Animals; Free Radicals; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Techniqu | 1991 |
Role of purines and xanthine oxidase in reperfusion injury in perfused rat liver.
Topics: Animals; Female; Hypoxanthine; Hypoxanthines; L-Lactate Dehydrogenase; Liver Circulation; Malondiald | 1989 |
Xanthine and hypoxanthine accumulation during storage may contribute to reperfusion injury following liver transplantation in the rat.
Topics: Animals; Cell Survival; Female; Hypertonic Solutions; Hypoxanthine; Hypoxanthines; Liver; Liver Tran | 1989 |
Potential role of mitochondrial calcium metabolism during reperfusion injury.
Topics: Animals; Calcium; Catalase; Hypoxanthine; Hypoxanthines; Kidney; Kinetics; Male; Mitochondria; NAD; | 1989 |