Page last updated: 2024-10-21

xanthine and Hypoxia

xanthine has been researched along with Hypoxia in 40 studies

7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"The present study revealed that hypoxanthine was secreted from human adipose tissue, and the secretion might be increased in local hypoxia."7.88Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia. ( Bamba, T; Fujishima, Y; Fukata, T; Fukusaki, E; Funahashi, T; Furuno, M; Kita, S; Maeda, N; Mizushima, T; Mori, M; Nagao, H; Nishizawa, H; Shimomura, I; Tanaka, Y; Tsushima, Y, 2018)
" Rats which survived hypoglycemia by insulin, hypoxia by 10% O2, or ischemia by carotid ligation and hypotension to 40 mm Hg, evidenced no changes in cerebrospinal fluid (CSF) uridine."7.68Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection. ( Breese, GR; Hunt, RD; Lundberg, C; McCown, TJ; Mueller, RA, 1990)
"Previously, we developed a pharmacokinetic-pharmacodynamic model of allopurinol, oxypurinol, and biomarkers, hypoxanthine, xanthine, and uric acid, in neonates with hypoxic-ischemic encephalopathy, in which high initial biomarker levels were observed suggesting an impact of hypoxia."4.12Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates. ( Allegaert, K; Chu, WY; Dorlo, TPC; Huitema, ADR, 2022)
"The present study revealed that hypoxanthine was secreted from human adipose tissue, and the secretion might be increased in local hypoxia."3.88Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia. ( Bamba, T; Fujishima, Y; Fukata, T; Fukusaki, E; Funahashi, T; Furuno, M; Kita, S; Maeda, N; Mizushima, T; Mori, M; Nagao, H; Nishizawa, H; Shimomura, I; Tanaka, Y; Tsushima, Y, 2018)
" Total hydroperoxides (TH) and advanced oxidation protein products (AOPP) as indices of oxidative stress, xanthine (Xa) and hypoxanthine (Hx) as indices of hypoxia, alpha1-microglobulin and N-acetyl-beta-D-glucosaminidase (NAG) as indices of kidney damage were assayed."3.74Oxidative kidney damage in preterm newborns during perinatal period. ( Bellieni, CV; Buonocore, G; Cataldi, L; Fanos, V; Longini, M; Mussap, M; Perrone, S; Proietti, F, 2007)
"Lactate accumulation, amino acid aspartate and glutamate levels, and hypoxanthine, xanthine and malondialdehyde (MDA) concentrations were compared in neonate rat brain after transient global hypoxia induced alone or in association with unilateral ligation of a carotid artery."3.70Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia. ( Barrier, L; Chalon, S; Guerraoui, A; Guilloteau, D; Huguet, F; Tallineau, C, 1998)
"Flux through the adenosine production and degradation pathways is transiently increased during hypoxia."3.68Interstitial purine metabolites and lactate during regional myocardial hypoxia. ( Downey, HF; Van Wylen, DG; Williams, AG, 1993)
"The role of xanthine oxidase and oxygen free radicals in postischemic reperfusion injury in the rat kidney remains controversial."3.68Minimal role of xanthine oxidase and oxygen free radicals in rat renal tubular reoxygenation injury. ( Doctor, RB; Mandel, LJ, 1991)
" Rats which survived hypoglycemia by insulin, hypoxia by 10% O2, or ischemia by carotid ligation and hypotension to 40 mm Hg, evidenced no changes in cerebrospinal fluid (CSF) uridine."3.68Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection. ( Breese, GR; Hunt, RD; Lundberg, C; McCown, TJ; Mueller, RA, 1990)
" This study tests the hypothesis that there is a direct relationship between periods of hypotension and body fluid uric acid and oxypurine levels in 19 prospectively studied patients."3.67Increased body fluid purine levels during hypotensive events. Evidence for ATP degradation. ( Fox, IH; Woolliscroft, JO, 1986)
"Measurement of hypoxanthine/xanthine has been suggested to be a useful indicator of cellular hypoxia."3.67Cellular hypoxia during hemodialysis. Demonstration of intradialytic release of purine and pyrimidine metabolites. ( Knudsen, F; Thorgaard Andersen, P, 1985)
" However, PFC emulsions are not resuscitation fluids because PFCs only work optimally in the presence of high O2 partial pressure (hyperoxia); moreover, because they have no oncotic potential, dosing limitations prevent their use to permanently replace large hemorrhage volumes."2.71Oxygent as a top load to colloid and hyperoxia is more effective in resuscitation from hemorrhagic shock than colloid and hyperoxia alone. ( Bottino, D; Faithfull, S; Habler, OP; Keipert, PE; Kemming, GI; Meier, J; Meisner, FG; Minor, T; Packert, KB; Thiel, M; Tillmanns, J; Wojtczyk, CJ, 2005)
"To test whether intermittent hypoxemia could, in part, explain this observed difference, Hx, xanthine (X), and uric acid were measured in vitreous humor, urine, plasma, and cerebrospinal fluid in newborn piglets during intermittent hypoxemia (IH) or continuous hypoxemia (CH) of equal degree and duration."1.29Hypoxanthine, xanthine, and uric acid concentrations in plasma, cerebrospinal fluid, vitreous humor, and urine in piglets subjected to intermittent versus continuous hypoxemia. ( Oyasaeter, S; Rognum, TO; Rootwelt, T; Saugstad, OD; Stoltenberg, L, 1993)
"Both groups underwent hypoxemia for 2 hrs and then underwent reoxygenation for 1 hr (group 1 with an FIO2 of 1."1.29Hypoxanthine, xanthine, and uric acid in newborn pigs during hypoxemia followed by resuscitation with room air or 100% oxygen. ( Oyasaeter, S; Poulsen, JP; Saugstad, OD, 1993)
"It is concluded that SIDS is probably not a sudden event, but may be preceded by relatively long, or repeated intermittent periods of hypoxia (of unknown etiology)."1.29Post-mortem concentrations of hypoxanthine in the vitreous humor--a comparison between babies with severe respiratory failure, congenital abnormalities of the heart, and victims of sudden infant death syndrome. ( Hauge, S; Oyasaeter, S; Poulsen, JP; Rognum, TO; Saugstad, OD, 1993)
"Acute hypoxemia defined by umbilical arterial oxygen pressure was accompanied by elevation of uric acid concentrations (P less than ."1.28Comparison of cord purine metabolites to maternal and neonatal variables of hypoxia. ( Benoit, R; O'Brien, WF; Porter, KB, 1992)
"Hypoxemia was induced in healthy humans in a low pressure chamber."1.28Increased plasma hypoxanthine values in humans during exposure to simulated altitude of 7,620 meters (25,000 feet). ( Dueland, AN; Dueland, S; Myhre, K; Saugstad, OD, 1991)
"During hypoxemia with arterial O2 tension between 2."1.28Hypoxanthine, xanthine, and uric acid concentrations in the cerebrospinal fluid, plasma, and urine of hypoxemic pigs. ( Oyasaeter, S; Poulsen, JP; Rognum, TO; Sanderud, J; Saugstad, OD, 1990)
"During hypoxemia with arterial O2 tension between 2."1.28Changes in oxypurine concentrations in vitreous humor of pigs during hypoxemia and post-mortem. ( Oyasaeter, S; Poulsen, JP; Rognum, TO; Saugstad, OD, 1990)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19907 (17.50)18.7374
1990's18 (45.00)18.2507
2000's10 (25.00)29.6817
2010's4 (10.00)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Chu, WY1
Allegaert, K1
Dorlo, TPC1
Huitema, ADR1
Nagao, H1
Nishizawa, H1
Tanaka, Y1
Fukata, T1
Mizushima, T1
Furuno, M1
Bamba, T1
Tsushima, Y1
Fujishima, Y1
Kita, S1
Funahashi, T1
Maeda, N1
Mori, M2
Fukusaki, E1
Shimomura, I1
Rajapakse, A1
Linder, C1
Morrison, RD1
Sarkar, U1
Leigh, ND1
Barnes, CL1
Daniels, JS2
Gates, KS2
Thomas, R1
Lee, J1
Chevalier, V1
Sadler, S1
Selesniemi, K1
Hatfield, S1
Sitkovsky, M1
Ondrechen, MJ1
Jones, GB1
Ngu, LH1
Afroze, B1
Chen, BC1
Affandi, O1
Zabedah, MY1
Chou, TF1
Ma, MC1
Tsai, CP1
Chen, CF1
Martin, RJ2
Di Fiore, JM1
Macfarlane, PM1
Wilson, CG1
Li, H1
Samouilov, A1
Liu, X1
Zweier, JL1
Abu-Shaweesh, JM1
Baird, TM1
Kemming, GI1
Meisner, FG1
Wojtczyk, CJ1
Packert, KB1
Minor, T1
Thiel, M1
Tillmanns, J1
Meier, J1
Bottino, D1
Keipert, PE1
Faithfull, S1
Habler, OP1
Perrone, S1
Mussap, M1
Longini, M1
Fanos, V1
Bellieni, CV1
Proietti, F1
Cataldi, L1
Buonocore, G1
Harkness, RA1
Simmonds, RJ1
Coade, SB1
Yamaguchi, K1
Asano, K1
Takasugi, T1
Kawai, A1
Umeda, A1
Kawashiro, T1
Yokoyama, T1
Stoltenberg, L1
Rootwelt, T1
Oyasaeter, S5
Rognum, TO4
Saugstad, OD7
Van Wylen, DG1
Williams, AG1
Downey, HF1
Castro-Gago, M1
Rodríguez-Segade, S1
Camiña, F1
Bollar, A1
Rodríguez-Núñez, A1
Poulsen, JP5
Hauge, S1
Huguet, F1
Guerraoui, A1
Barrier, L1
Guilloteau, D1
Tallineau, C1
Chalon, S1
Pastuszko, P1
Marro, P1
Delivoria-Papadopoulos, M1
Wilson, DF1
Mei, DA1
Nithipatikom, K1
Lasley, RD1
Gross, GJ1
Prezelj, M1
Neubauer, D1
Derganc, M1
Malek, A1
Sager, R1
Schneider, H1
Ganley, B1
Chowdhury, G1
Bhansali, J1
Rogers, MS1
Murray, HG1
Wang, CC1
Pennell, CE1
Turner, A1
Yan, P1
Pang, CC1
Chang, AM1
Porter, KB1
O'Brien, WF1
Benoit, R1
Dueland, S1
Myhre, K1
Dueland, AN1
Doctor, RB1
Mandel, LJ1
Gardiner, EE1
Newberry, RC1
Keng, JY1
Mueller, RA1
McCown, TJ1
Hunt, RD1
Lundberg, C1
Breese, GR1
Sanderud, J1
Tarantola, M1
Motterlini, R1
Beretta, M1
Rovida, E1
Samaja, M1
Kjellmer, I1
Andiné, P1
Hagberg, H1
Thiringer, K1
Stípek, S1
Novák, L1
Vinklár, P1
Trojan, S1
Stastný, F1
Phillis, JW1
O'Regan, MH1
Walter, GA1
Woolliscroft, JO1
Fox, IH1
Armiger, LC1
Hollis, DG1
Seelye, RN1
Knudsen, F1
Thorgaard Andersen, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
WAVE Trial in Premature Infants With Apnea of Prematurity Using a Simple, Non-invasive Vibratory Device to Study the Effectiveness in Supporting Breathing and General Stability[NCT04528030]17 participants (Anticipated)Interventional2021-04-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for xanthine and Hypoxia

ArticleYear
Physiologic basis for intermittent hypoxic episodes in preterm infants.
    Advances in experimental medicine and biology, 2012, Volume: 758

    Topics: Chemoreceptor Cells; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Morbidity; Oxygen; Respira

2012
Apnoea of prematurity.
    Paediatric respiratory reviews, 2004, Volume: 5 Suppl A

    Topics: Apnea; Continuous Positive Airway Pressure; Humans; Hypercapnia; Hypoxia; Infant, Newborn; Infant, P

2004

Trials

1 trial available for xanthine and Hypoxia

ArticleYear
Oxygent as a top load to colloid and hyperoxia is more effective in resuscitation from hemorrhagic shock than colloid and hyperoxia alone.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:3

    Topics: Animals; Body Weight; Colloids; Contrast Media; Dogs; Fluorocarbons; Hematocrit; Hemodynamics; Hemor

2005

Other Studies

37 other studies available for xanthine and Hypoxia

ArticleYear
Semi-mechanistic Modeling of Hypoxanthine, Xanthine, and Uric Acid Metabolism in Asphyxiated Neonates.
    Clinical pharmacokinetics, 2022, Volume: 61, Issue:11

    Topics: Allopurinol; Clinical Studies as Topic; Humans; Hypoxanthine; Hypoxia; Hypoxia-Ischemia, Brain; Infa

2022
Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia.
    Obesity (Silver Spring, Md.), 2018, Volume: 26, Issue:7

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Adipose Tissue, White; Adolescent; Adult; Animals; Cells,

2018
Enzymatic conversion of 6-nitroquinoline to the fluorophore 6-aminoquinoline selectively under hypoxic conditions.
    Chemical research in toxicology, 2013, Apr-15, Volume: 26, Issue:4

    Topics: Aminoquinolines; Hypoxia; Nitroquinolines; Xanthine; Xanthine Oxidase

2013
Design and evaluation of xanthine based adenosine receptor antagonists: potential hypoxia targeted immunotherapies.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Cell Line; Crystallography, X-Ray; Drug Design; Humans; Hypoxia; Immunotherapy; Models, Molecular; P

2013
Molybdenum cofactor deficiency in a Malaysian child.
    Singapore medical journal, 2009, Volume: 50, Issue:10

    Topics: Brain Diseases; Child; Coenzymes; Cysteine; Diagnosis, Differential; Humans; Hypoxanthine; Hypoxia;

2009
Enhancement of superoxide dismutase activity in rat lungs after hypoxic preconditioning.
    The Chinese journal of physiology, 2009, Nov-30, Volume: 52, Issue:5 Suppl

    Topics: Adaptation, Physiological; Animals; Antioxidants; Female; Hemodynamics; Hypoxia; Lung; Rats; Rats, W

2009
Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrate reduction: evaluation of its role in nitrite and nitric oxide generation in anoxic tissues.
    Biochemistry, 2003, Feb-04, Volume: 42, Issue:4

    Topics: Animals; Catalysis; Electrochemistry; Electron Spin Resonance Spectroscopy; Hypoxia; Kinetics; Lumin

2003
Oxidative kidney damage in preterm newborns during perinatal period.
    Clinical biochemistry, 2007, Volume: 40, Issue:9-10

    Topics: Acetylglucosaminidase; Alpha-Globulins; Female; Humans; Hydrogen Peroxide; Hypoxanthine; Hypoxia; In

2007
Effect of hypoxia and exercise on nucleotide metabolism in man.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt B

    Topics: Adenosine Triphosphate; Adult; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Kinetics; Male

1984
Roles of antioxidant enzymes in erythrocytes on hypoxic pulmonary vasoconstriction.
    Advances in experimental medicine and biology, 1994, Volume: 345

    Topics: Animals; Antioxidants; Catalase; Erythrocytes; Glutathione Peroxidase; Hypoxia; In Vitro Techniques;

1994
Hypoxanthine, xanthine, and uric acid concentrations in plasma, cerebrospinal fluid, vitreous humor, and urine in piglets subjected to intermittent versus continuous hypoxemia.
    Pediatric research, 1993, Volume: 34, Issue:6

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Hypoxanthine; Hypoxanthines; Hypo

1993
Interstitial purine metabolites and lactate during regional myocardial hypoxia.
    Cardiovascular research, 1993, Volume: 27, Issue:8

    Topics: Adenosine; Animals; Cardiomyopathies; Coronary Circulation; Dialysis; Dogs; Extracellular Space; Fem

1993
Indicators of hypoxia in cerebrospinal fluid of hydrocephalic children with suspected shunt malfunction.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1993, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Equipment Failure; Female; H

1993
Hypoxanthine, xanthine, and uric acid in newborn pigs during hypoxemia followed by resuscitation with room air or 100% oxygen.
    Critical care medicine, 1993, Volume: 21, Issue:7

    Topics: Air; Animals; Animals, Newborn; Cardiopulmonary Resuscitation; Female; Hypoxanthine; Hypoxanthines;

1993
Post-mortem concentrations of hypoxanthine in the vitreous humor--a comparison between babies with severe respiratory failure, congenital abnormalities of the heart, and victims of sudden infant death syndrome.
    Journal of perinatal medicine, 1993, Volume: 21, Issue:2

    Topics: Heart Defects, Congenital; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Infant; Infant, Newborn; Po

1993
Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia.
    Neuroscience letters, 1998, Jan-09, Volume: 240, Issue:2

    Topics: Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Energy Metabolism; Excitatory Amino

1998
Response of purine metabolism and cortical oxygen pressure to hypoxia and reoxygenation in newborn piglets.
    Advances in experimental medicine and biology, 1997, Volume: 428

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebral Cortex; Hypoxanthine; Hypoxia; Inosine; Oxygen; Pa

1997
Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:6

    Topics: Adenine Nucleotides; Adenosine; Animals; Benzopyrans; Dihydropyridines; Dogs; Extracellular Space; H

1998
Measurement of purines in urine by capillary electrophoresis for estimating the degree of hypoxia in infants.
    Clinical chemistry and laboratory medicine, 2000, Volume: 38, Issue:7

    Topics: Buffers; Calibration; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Hypoxanthine;

2000
Effect of hypoxia, oxidative stress and lipopolysaccharides on the release of prostaglandins and cytokines from human term placental explants.
    Placenta, 2001, Volume: 22 Suppl A

    Topics: Adult; Cell Hypoxia; Chorionic Villi; Culture Techniques; Cyclooxygenase Inhibitors; Cytokines; Drug

2001
Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxide.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:9

    Topics: Antibiotics, Antineoplastic; DNA; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Pol

2001
Oxidative stress in the fetal lamb brain following intermittent umbilical cord occlusion: a path analysis.
    BJOG : an international journal of obstetrics and gynaecology, 2001, Volume: 108, Issue:12

    Topics: Animals; Brain; Fetus; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxia; Lipid P

2001
Comparison of cord purine metabolites to maternal and neonatal variables of hypoxia.
    Obstetrics and gynecology, 1992, Volume: 79, Issue:3

    Topics: Asphyxia Neonatorum; Female; Fetal Blood; Fetal Monitoring; Heart Rate, Fetal; Humans; Hydrogen-Ion

1992
Increased plasma hypoxanthine values in humans during exposure to simulated altitude of 7,620 meters (25,000 feet).
    Aviation, space, and environmental medicine, 1991, Volume: 62, Issue:11

    Topics: Adolescent; Adult; Altitude; Atmospheric Pressure; Carbon Dioxide; Female; Hemoglobins; Humans; Hypo

1991
Oxypurines in extracellular fluids from piglets during hypoxemia and reoxygenation.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Animals; Extracellular Space; Hypoxanthine; Hypoxanthines; Hypoxia; Kinetics; Oxygen; Swine; Time Fa

1991
Minimal role of xanthine oxidase and oxygen free radicals in rat renal tubular reoxygenation injury.
    Journal of the American Society of Nephrology : JASN, 1991, Volume: 1, Issue:7

    Topics: Adenine Nucleotides; Animals; Free Radicals; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Techniqu

1991
Avian vitreous humor concentrations of inosine, hypoxanthine, xanthine, uric acid, uracil and uridine as influenced by age and sex: their relevance as indicators of ante-mortem hypoxia.
    Forensic science international, 1990, Volume: 47, Issue:2

    Topics: Age Factors; Animals; Chickens; Female; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male;

1990
Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection.
    Cellular and molecular neurobiology, 1990, Volume: 10, Issue:3

    Topics: Animals; Blood; Brain Ischemia; Heart Arrest; Hypoglycemia; Hypoxanthine; Hypoxanthines; Hypoxia; In

1990
Hypoxanthine, xanthine, and uric acid concentrations in the cerebrospinal fluid, plasma, and urine of hypoxemic pigs.
    Pediatric research, 1990, Volume: 28, Issue:5

    Topics: Animals; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Male; Oxygen; Swine; Uric Acid; Xanthine; Xan

1990
Changes in oxypurine concentrations in vitreous humor of pigs during hypoxemia and post-mortem.
    Pediatric research, 1990, Volume: 28, Issue:5

    Topics: Animals; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Male; Postmortem Changes; Purinones; Swine; T

1990
Impairment of the post-anoxic recovery of isolated rat hearts by intravascular hypoxanthine and xanthine.
    Biomaterials, artificial cells, and artificial organs, 1990, Volume: 18, Issue:2

    Topics: Animals; Blood Substitutes; Free Radicals; Heart; Hypoxanthine; Hypoxanthines; Hypoxia; In Vitro Tec

1990
Extracellular increase of hypoxanthine and xanthine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia.
    Brain research, 1989, Jan-30, Volume: 478, Issue:2

    Topics: Animals; Basal Ganglia; Cerebral Cortex; Evoked Potentials, Somatosensory; Extracellular Space; Fetu

1989
Plasma xanthine oxidase activity correlates with the resistance to severe hypoxia in different species.
    Physiologia Bohemoslovaca, 1988, Volume: 37, Issue:2

    Topics: Animals; Cricetinae; Female; Guinea Pigs; Hypoxanthine; Hypoxanthines; Hypoxia; Mice; Polarography;

1988
Effects of deoxycoformycin on adenosine, inosine, hypoxanthine, xanthine, and uric acid release from the hypoxemic rat cerebral cortex.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1988, Volume: 8, Issue:5

    Topics: Adenosine; Animals; Cerebral Cortex; Coformycin; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male

1988
Increased body fluid purine levels during hypotensive events. Evidence for ATP degradation.
    The American journal of medicine, 1986, Volume: 81, Issue:3

    Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Body Fluids; Creatinine; Humans; Hypotension; Hypox

1986
Regional variations in the "adenine/oxypurine" pool of the heart in normoxia and oxygen deficiency.
    Experimental pathology, 1986, Volume: 30, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Animals; Chromatography, High Pressure Liquid; Dogs; Energy Metaboli

1986
Cellular hypoxia during hemodialysis. Demonstration of intradialytic release of purine and pyrimidine metabolites.
    Blood purification, 1985, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Female; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Kidney Failure, Chronic; Ki

1985
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