Page last updated: 2024-10-21

xanthine and Hypotension

xanthine has been researched along with Hypotension in 5 studies

7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"First, this investigation showed that plasma levels of inosine, hypoxanthine, and xanthine, which are metabolites of adenosine, rose sharply when blood pressure dropped suddenly along with symptoms during a hemodialysis session (sudden hypotension), but not when it decreased gradually with eventual symptoms (gradual hypotension)."9.07Role of adenosine in dialysis-induced hypotension. ( Inoue, I; Maeda, K; Miwa, M; Morita, H; Nakai, S; Odani, H; Shinzato, T, 1994)
"First, this investigation showed that plasma levels of inosine, hypoxanthine, and xanthine, which are metabolites of adenosine, rose sharply when blood pressure dropped suddenly along with symptoms during a hemodialysis session (sudden hypotension), but not when it decreased gradually with eventual symptoms (gradual hypotension)."5.07Role of adenosine in dialysis-induced hypotension. ( Inoue, I; Maeda, K; Miwa, M; Morita, H; Nakai, S; Odani, H; Shinzato, T, 1994)
"Values of guanosine, inosine, hypoxanthine, xanthine and uridine were significantly higher, while ECBA was significantly lower after hemorrhagic hypotension than control values."3.73Purine and pyrimidine metabolism and electrocortical brain activity during hypotension in near-term lambs. ( de Abreu, R; Hopman, J; van de Bor, M; van Os, S; Wethly, K, 2006)
"Cerebral blood flow (CBF, by laser Doppler flowmetry) and extracellular cortical concentrations (by microdialysis) of adenosine, inosine, xanthine, hypoxanthine, and lactate were measured together with somatosensory evoked potentials (SEP) in chloralose-anaesthetized spontaneously hypertensive rats (SHR) during relative cerebral ischemia induced by hypotensive hemorrhage."3.67Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites. ( Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P, 1989)
" This study tests the hypothesis that there is a direct relationship between periods of hypotension and body fluid uric acid and oxypurine levels in 19 prospectively studied patients."3.67Increased body fluid purine levels during hypotensive events. Evidence for ATP degradation. ( Fox, IH; Woolliscroft, JO, 1986)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okudaira, S1
Suzuki, S1
van Os, S1
de Abreu, R1
Hopman, J1
Wethly, K1
van de Bor, M1
Shinzato, T1
Miwa, M1
Nakai, S1
Morita, H1
Odani, H1
Inoue, I1
Maeda, K1
Skarphedinsson, JO1
Sandberg, M1
Hagberg, H1
Carlsson, S1
Thorén, P1
Woolliscroft, JO1
Fox, IH1

Trials

1 trial available for xanthine and Hypotension

ArticleYear
Role of adenosine in dialysis-induced hypotension.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 4, Issue:12

    Topics: Adenosine; Aged; Caffeine; Female; Humans; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Male;

1994

Other Studies

4 other studies available for xanthine and Hypotension

ArticleYear
Influence of spinal hypotension on fetal oxidative status during elective cesarean section in uncomplicated pregnancies.
    Archives of gynecology and obstetrics, 2005, Volume: 271, Issue:4

    Topics: Adult; Anesthesia, Spinal; Blood Gas Analysis; Blood Glucose; Carbon Dioxide; Cesarean Section; Fema

2005
Purine and pyrimidine metabolism and electrocortical brain activity during hypotension in near-term lambs.
    Biology of the neonate, 2006, Volume: 89, Issue:1

    Topics: Animals; Animals, Newborn; Brain; Electroencephalography; Guanosine; Hemorrhage; Hypotension; Hypoxa

2006
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:3

    Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extrace

1989
Increased body fluid purine levels during hypotensive events. Evidence for ATP degradation.
    The American journal of medicine, 1986, Volume: 81, Issue:3

    Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Body Fluids; Creatinine; Humans; Hypotension; Hypox

1986