xanthine has been researched along with Chagas Disease in 1 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chagas disease affects 8 million people worldwide and remains a main cause of death due to heart failure in Latin America." | 1.42 | Lead identification to clinical candidate selection: drugs for Chagas disease. ( Arkin, M; Bryant, C; Chatterjee, AK; Chen, S; Gallardo-Godoy, A; Glynne, R; Gut, J; Kellar, D; Khare, S; McKerrow, J; Molteni, V; Neitz, RJ; Renslo, AR; Roach, SL; Robertson, S; Siqueira-Neto, JL; Stinson, M; Supek, F; Yeh, V, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Neitz, RJ | 1 |
| Chen, S | 1 |
| Supek, F | 1 |
| Yeh, V | 1 |
| Kellar, D | 1 |
| Gut, J | 1 |
| Bryant, C | 1 |
| Gallardo-Godoy, A | 1 |
| Molteni, V | 1 |
| Roach, SL | 1 |
| Khare, S | 1 |
| Stinson, M | 1 |
| Chatterjee, AK | 1 |
| Robertson, S | 1 |
| Renslo, AR | 1 |
| Arkin, M | 1 |
| Glynne, R | 1 |
| McKerrow, J | 1 |
| Siqueira-Neto, JL | 1 |
1 other study available for xanthine and Chagas Disease
| Article | Year |
|---|---|
Lead identification to clinical candidate selection: drugs for Chagas disease.
Topics: Animals; Cell Line; Chagas Disease; Colorimetry; Disease Models, Animal; Drug Discovery; Drug Evalua | 2015 |