xanthine has been researched along with Brain Ischemia in 16 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Rats which survived hypoglycemia by insulin, hypoxia by 10% O2, or ischemia by carotid ligation and hypotension to 40 mm Hg, evidenced no changes in cerebrospinal fluid (CSF) uridine." | 7.68 | Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection. ( Breese, GR; Hunt, RD; Lundberg, C; McCown, TJ; Mueller, RA, 1990) |
| "Global cerebral ischemia of 10 minutes duration was induced in newborn pigs anesthetized with isoflurane by occlusion of subclavian and brachiocephalic arteries; cortical cerebral blood flow (CBF) and interstitial adenosine concentration were evaluated simultaneously using the combined hydrogen clearance/microdialysis technique." | 5.29 | Effect of hypoglycemia on postischemic cortical blood flow, hypercapnic reactivity, and interstitial adenosine concentration. ( Gidday, JM; Gonzales, ER; Kim, YB; Park, TS; Shah, AR, 1994) |
| "Lactate accumulation, amino acid aspartate and glutamate levels, and hypoxanthine, xanthine and malondialdehyde (MDA) concentrations were compared in neonate rat brain after transient global hypoxia induced alone or in association with unilateral ligation of a carotid artery." | 3.70 | Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia. ( Barrier, L; Chalon, S; Guerraoui, A; Guilloteau, D; Huguet, F; Tallineau, C, 1998) |
| " Rats which survived hypoglycemia by insulin, hypoxia by 10% O2, or ischemia by carotid ligation and hypotension to 40 mm Hg, evidenced no changes in cerebrospinal fluid (CSF) uridine." | 3.68 | Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection. ( Breese, GR; Hunt, RD; Lundberg, C; McCown, TJ; Mueller, RA, 1990) |
| "Cerebral blood flow (CBF, by laser Doppler flowmetry) and extracellular cortical concentrations (by microdialysis) of adenosine, inosine, xanthine, hypoxanthine, and lactate were measured together with somatosensory evoked potentials (SEP) in chloralose-anaesthetized spontaneously hypertensive rats (SHR) during relative cerebral ischemia induced by hypotensive hemorrhage." | 3.67 | Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites. ( Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P, 1989) |
| "Cerebral hypoxanthine, xanthine, and uric acid levels were measured by high-performance liquid chromatography (HPLC) for up to 4 hours following focal cerebral ischemia in the rat." | 3.67 | [Early changes of oxypurines in rat brain following focal cerebral ischemia]. ( Nihei, H, 1988) |
| "In addition, it was found that global cerebral ischemia induced a statistically significant decrease of the hippocampal Na(+),K(+)-ATPase activity starting from 1 to 168 h of reperfusion." | 1.32 | Hyperbaric oxygen treatment: the influence on the hippocampal superoxide dismutase and Na+,K+-ATPase activities in global cerebral ischemia-exposed rats. ( Antoncić, I; Filipović, T; Mrsić-Pelcić, J; Pelcić, G; Simonić, A; Vitezić, D; Zupan, G, 2004) |
| "Global cerebral ischemia of 10 minutes duration was induced in newborn pigs anesthetized with isoflurane by occlusion of subclavian and brachiocephalic arteries; cortical cerebral blood flow (CBF) and interstitial adenosine concentration were evaluated simultaneously using the combined hydrogen clearance/microdialysis technique." | 1.29 | Effect of hypoglycemia on postischemic cortical blood flow, hypercapnic reactivity, and interstitial adenosine concentration. ( Gidday, JM; Gonzales, ER; Kim, YB; Park, TS; Shah, AR, 1994) |
| "Adenosine, which also increases during cerebral ischemia, is proposed to inhibit neurotransmitter release." | 1.28 | Adenosine receptor blockade augments interstitial fluid levels of excitatory amino acids during cerebral ischemia. ( Grabb, MC; Roche, FM; Sciotti, VM; Van Wylen, DG, 1992) |
| "Xanthine oxidase was assayed by high pressure liquid chromatography using ultraviolet and electrochemical detection." | 1.28 | Ischaemic brain oedema and xanthine-xanthine oxidase system. ( Ishikawa, M; Kikuchi, H; Kinuta, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mrsić-Pelcić, J | 1 |
| Pelcić, G | 1 |
| Vitezić, D | 1 |
| Antoncić, I | 1 |
| Filipović, T | 1 |
| Simonić, A | 1 |
| Zupan, G | 1 |
| Levin, SD | 1 |
| Brown, JK | 1 |
| Harkness, RA | 1 |
| Kim, YB | 1 |
| Gidday, JM | 1 |
| Gonzales, ER | 1 |
| Shah, AR | 1 |
| Park, TS | 1 |
| Kuracka, L | 1 |
| Kalnovicová, T | 1 |
| Líska, B | 1 |
| Turcáni, P | 1 |
| Huguet, F | 1 |
| Guerraoui, A | 1 |
| Barrier, L | 1 |
| Guilloteau, D | 1 |
| Tallineau, C | 1 |
| Chalon, S | 1 |
| Satoh, T | 1 |
| Ishikawa, Y | 1 |
| Kataoka, Y | 1 |
| Cui, Y | 1 |
| Yanase, H | 1 |
| Kato, K | 1 |
| Watanabe, Y | 2 |
| Nakadate, K | 1 |
| Matsumura, K | 1 |
| Hatanaka, H | 1 |
| Kataoka, K | 1 |
| Noyori, R | 1 |
| Suzuki, M | 1 |
| Prough, DS | 1 |
| Bedell, EA | 1 |
| Akdemir, H | 1 |
| Aşik, Z | 1 |
| Paşaoğlu, H | 1 |
| Karaküçük, I | 1 |
| Oktem, IS | 1 |
| Koç, RK | 1 |
| Sciotti, VM | 1 |
| Roche, FM | 1 |
| Grabb, MC | 1 |
| Van Wylen, DG | 1 |
| Pellegrini-Giampietro, DE | 1 |
| Cherici, G | 1 |
| Alesiani, M | 1 |
| Carla, V | 1 |
| Moroni, F | 1 |
| Kinuta, Y | 1 |
| Kikuchi, H | 1 |
| Ishikawa, M | 1 |
| Mueller, RA | 1 |
| McCown, TJ | 1 |
| Hunt, RD | 1 |
| Lundberg, C | 1 |
| Breese, GR | 1 |
| Skarphedinsson, JO | 1 |
| Sandberg, M | 2 |
| Hagberg, H | 2 |
| Carlsson, S | 1 |
| Thorén, P | 1 |
| Andersson, P | 1 |
| Butcher, S | 1 |
| Lehmann, A | 1 |
| Hamberger, A | 1 |
| Nihei, H | 1 |
| Betz, AL | 1 |
1 review available for xanthine and Brain Ischemia
| Article | Year |
|---|---|
Cerebral ischemia in humans after traumatic brain injury.
Topics: Adenosine; Brain Chemistry; Brain Injuries; Brain Ischemia; Extracellular Space; Humans; Jugular Vei | 2001 |
15 other studies available for xanthine and Brain Ischemia
| Article | Year |
|---|---|
Hyperbaric oxygen treatment: the influence on the hippocampal superoxide dismutase and Na+,K+-ATPase activities in global cerebral ischemia-exposed rats.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Hippocampus; Hyperbaric Oxygenation; Rats; Rats, Wi | 2004 |
Cerebrospinal fluid hypoxanthine and xanthine concentrations as indicators of metabolic damage due to raised intracranial pressure in hydrocephalic children.
Topics: Adolescent; Brain Diseases, Metabolic; Brain Ischemia; Child; Child, Preschool; Energy Metabolism; H | 1984 |
Effect of hypoglycemia on postischemic cortical blood flow, hypercapnic reactivity, and interstitial adenosine concentration.
Topics: Adenosine; Animals; Animals, Newborn; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Corte | 1994 |
HPLC method for measurement of purine nucleotide degradation products in cerebrospinal fluid.
Topics: Adult; Brain Ischemia; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hyp | 1996 |
Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Energy Metabolism; Excitatory Amino | 1998 |
CNS-specific prostacyclin ligands as neuronal survival-promoting factors in the brain.
Topics: Animals; Autoradiography; Brain Ischemia; Cell Death; Cell Survival; Central Nervous System; Epopros | 1999 |
The effect of allopurinol on focal cerebral ischaemia: an experimental study in rabbits.
Topics: Allopurinol; Animals; Blood Gas Analysis; Blood Glucose; Brain Ischemia; Chromatography, High Pressu | 2001 |
Adenosine receptor blockade augments interstitial fluid levels of excitatory amino acids during cerebral ischemia.
Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebrovascular Circulation; Glutamates; Glutamic Acid; Hypo | 1992 |
Excitatory amino acid release and free radical formation may cooperate in the genesis of ischemia-induced neuronal damage.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Free Radicals; Glutamates; Glutamic Acid; Male; | 1990 |
Ischaemic brain oedema and xanthine-xanthine oxidase system.
Topics: Animals; Brain Edema; Brain Ischemia; Chromatography, High Pressure Liquid; Male; Rats; Rats, Inbred | 1990 |
Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection.
Topics: Animals; Blood; Brain Ischemia; Heart Arrest; Hypoglycemia; Hypoxanthine; Hypoxanthines; Hypoxia; In | 1990 |
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extrace | 1989 |
Blockade of N-methyl-D-aspartate-sensitive acidic amino acid receptors inhibits ischemia-induced accumulation of purine catabolites in the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Brain Ischemia; Corpus Striatum; Hypoxanthine; Hypo | 1986 |
[Early changes of oxypurines in rat brain following focal cerebral ischemia].
Topics: Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; M | 1988 |
Identification of hypoxanthine transport and xanthine oxidase activity in brain capillaries.
Topics: Adenine; Allopurinol; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Ischemia; Cap | 1985 |