xanthine has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.
9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Volterra, A | 1 |
| Trotti, D | 1 |
| Floridi, S | 1 |
| Racagni, G | 1 |
| Liochev, SI | 1 |
| Chen, LL | 1 |
| Hallewell, RA | 1 |
| Fridovich, I | 1 |
1 review available for xanthine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Reactive oxygen species inhibit high-affinity glutamate uptake: molecular mechanism and neuropathological implications.
Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Astrocytes; | 1994 |
1 other study available for xanthine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Superoxide-dependent peroxidase activity of H48Q: a superoxide dismutase variant associated with familial amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Binding Sites; Cloning, Molecular; Copper; Cytochrome c Group; Escher | 1997 |