xanthenes has been researched along with Colonic Neoplasms in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.08) | 18.7374 |
| 1990's | 30 (61.22) | 18.2507 |
| 2000's | 16 (32.65) | 29.6817 |
| 2010's | 1 (2.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arie, K; Haba, R; Hirakawa, E; Nakamura, M; Norimatsu, Y; Ohsaki, H | 1 |
| Baguley, BC; Ching, LM; Kestell, P; Zhao, L | 2 |
| Baguley, BC; Ching, LM; Newth, AL; Schooltink, MA; Woon, ST; Zwain, S | 1 |
| Azemovic, D; Massoumi, R; Nielsen, CK; Sjölander, A | 1 |
| Wang, H; Xu, H; Yang, X; Zhang, Z | 1 |
| Baguley, BC; Ching, LM; Drummond, CJ; Kieda, C; Reddy, CB; Schooltink, MA; Woon, ST | 1 |
| Baguley, BC; Ching, LM; Gummer, BH; Joseph, WR; Palmer, BD; Xu, ZF | 1 |
| Baguley, BC; Ching, LM; Philpott, M | 1 |
| Bibby, MC; Double, JA; Laws, AL; Matthew, AM | 1 |
| Baguley, BC; Gavin, JB; Wilson, WR; Zwi, LJ | 2 |
| Baguley, BC; Ching, LM; Joseph, WR; Zhuang, L | 1 |
| Baguley, BC; Cole, G; Li, Z; Thomsen, LL | 1 |
| Berk, DA; Jain, RK; Leunig, M; Yuan, F | 1 |
| Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E | 1 |
| Anees, M | 1 |
| Baguley, BC; Kestell, P; Zhuang, L | 1 |
| Baguley, BC; Browne, WL; Ching, LM; Gregory, T; Palmer, BD; Tchernegovski, R | 1 |
| Baguley, BC; Cao, Z; Ching, LM; Joseph, WR; Pang, JH | 1 |
| Baguley, BC; Browne, WL; Cao, Z; Ching, LM; Joseph, WR; Mountjoy, KG; Palmer, BD | 1 |
| Baguley, BC; Ching, LM; Goldsmith, D; Joseph, WR; Körner, H; Sedgwick, JD | 1 |
| James, ND; Latham, JP; Mautner, V; Searle, PF | 1 |
| Hasegawa, M; Hashimoto, Y; Kamei, H; Koide, T; Kojima, T | 1 |
| Baguley, BC; Ching, LM; Kestell, P; Muller, G; Palmer, BD; Paxton, JW; Zhao, L | 1 |
| Harada, Y; Hirai, H; Imanishi, J; Iwai, M; Kashima, K; Maruyama-Tabata, H; Mazda, O; Mori, T; Morikawa, T; Muramatsu, A; Okanoue, T; Satoh, E; Tanaka, S | 1 |
| Hara, A; Katayama, M; Kuno, T; Matsunaga, K; Mori, H; Qiao, Z; Yamada, Y; Yamahara, J; Yoshimi, N | 1 |
| Baguley, BC; Cao, Z; Ching, LM | 1 |
| Baguley, BC; Ching, LM; Kestell, P; Philpott, M; Zhao, L; Zhuang, L | 1 |
| Clardy, J; Wagenaar, MM | 1 |
| Beauregard, DA; Brindle, KM; Hill, SA; Pedley, RB | 1 |
| Barrero, AF; Christophersen, C; Justicia, J; Malmstrøm, J; Oltra, JE; Rosales, A | 1 |
| Baguley, BC; Cao, Z; Ching, LM; Jameson, MB; Kieda, C; Zwain, S | 1 |
| Baguley, BC; Ching, LM; Gavin, JB; Thomsen, LL | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Gamage, SA; Rewcastle, GW | 1 |
| Back, TT; Baguley, BC; Eader, L; Futami, H; Gruys, E; Wiltrout, RH; Young, HA | 1 |
| Baguley, BC; Ching, LM; Joseph, WR | 1 |
| Atwell, GJ; Baguley, BC; Ching, LM; Denny, WA; Joseph, WR; Rewcastle, GW; Zhuang, L | 1 |
| Baguley, BC; Kestell, P; McKeage, MJ | 1 |
| Atwell, GJ; Baguley, BC; Boyd, M; Denny, WA; Rewcastle, GW; Thomsen, LL; Zhuang, L | 1 |
| Baguley, BC; Ching, LM; Gavin, JB; Thomsen, LL; Zhuang, L | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Li, ZA; Rewcastle, GW | 1 |
| Atwell, GJ; Baguley, BC; Boyd, PD; Denny, WA; Palmer, BD; Rewcastle, GW | 1 |
| Davoust, J; Gorvel, JP; Jacquier, MF; Remy, L; Rigal, A | 1 |
| Baguley, BC; Ching, LM; Thomsen, LL | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Rewcastle, GW | 1 |
| Beck, WT; Horton, JK; Houghton, JA; Houghton, PJ; Qian, XD; Thimmaiah, KN | 1 |
| Adelstein, SJ; Kassis, AI; Kinsey, BM; Van den Abbeele, AD | 1 |
| Atwell, GJ; Baguley, BC; Calveley, SB; Denny, WA; Rewcastle, GW | 1 |
1 trial(s) available for xanthenes and Colonic Neoplasms
| Article | Year |
|---|---|
Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Blotting, Northern; Breast Neoplasms; Cells, Cultured; Chemokine CXCL10; Chemokines, CXC; Colonic Neoplasms; Endothelium, Vascular; Female; Humans; Interferons; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 2002 |
48 other study(ies) available for xanthenes and Colonic Neoplasms
| Article | Year |
|---|---|
Endometriosis of sigmoid colon mimicking malignant tumor diagnosed by intraoperative imprint cytology.
Topics: Azure Stains; Biopsy; Colon, Sigmoid; Colonic Neoplasms; Coloring Agents; Diagnosis, Differential; Endometriosis; Epithelial Cells; Female; Humans; Methylene Blue; Middle Aged; Xanthenes | 2012 |
The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Colonic Neoplasms; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neoplasm Transplantation; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Serotonin; Time Factors; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 2002 |
NF-kappa B activation in vivo in both host and tumour cells by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; NF-kappa B; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Xanthenes; Xanthones | 2003 |
Leukotriene D4-induced adhesion of Caco-2 cells is mediated by prostaglandin E2 and upregulation of alpha2beta1-integrin.
Topics: Caco-2 Cells; Carcinoma; Cell Adhesion; Colitis; Collagen Type I; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Extracellular Matrix; Humans; Integrin alpha2beta1; Isoenzymes; Leukotriene D4; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptors, Leukotriene; Sulfonamides; Up-Regulation; Xanthenes; Xanthones | 2003 |
Both calcium and ROS as common signals mediate Na(2)SeO(3)-induced apoptosis in SW480 human colonic carcinoma cells.
Topics: Acetylcysteine; Aniline Compounds; Apoptosis; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Catalase; Cell Line, Tumor; Cell Size; Cell Survival; Cobalt; Colonic Neoplasms; Dithiothreitol; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; Fluoresceins; Glutathione; Humans; Membrane Potentials; Mitochondria; Reactive Oxygen Species; Ruthenium Red; Sodium Selenite; Xanthenes | 2003 |
A comparison of the ability of DMXAA and xanthenone analogues to activate NF-kappaB in murine and human cell lines.
Topics: Animals; Antineoplastic Agents; Biological Assay; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Lymphoma, B-Cell; Mice; Necrosis; NF-kappa B; Structure-Activity Relationship; Xanthenes; Xanthones | 2005 |
Effect of thalidomide on tumour necrosis factor production and anti-tumour activity induced by 5,6-dimethylxanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Interactions; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Thalidomide; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1995 |
Induction of tumour necrosis factor-alpha by single and repeated doses of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid.
Topics: Aging; Animals; Antineoplastic Agents; Colonic Neoplasms; Crosses, Genetic; Dose-Response Relationship, Drug; Drug Administration Schedule; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1995 |
Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Colonic Neoplasms; Hemorrhage; Humans; Lung Neoplasms; Mice; Mice, Inbred Strains; Mice, Nude; Necrosis; Species Specificity; Tumor Cells, Cultured; Xanthenes; Xanthones | 1995 |
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Flavonoids; Immunity, Cellular; Male; Mice; Mice, Inbred Strains; Necrosis; Structure-Activity Relationship; Tumor Cells, Cultured; Xanthenes | 1994 |
Interaction between endotoxin and the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the induction of tumour necrosis factor and haemorrhagic necrosis of colon 38 tumours.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Endotoxins; Lipopolysaccharides; Mice; Necrosis; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1994 |
The morphological effects of the anti-tumor agents flavone acetic acid and 5,6-dimethyl xanthenone acetic acid on the colon 38 mouse tumor.
Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Apoptosis; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron; Necrosis; Phosphocreatine; Xanthenes; Xanthones | 1994 |
Serotonin involvement in the antitumour and host effects of flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyproheptadine; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Nitrates; Nitric Oxide; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1993 |
Microvascular permeability of albumin, vascular surface area, and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice.
Topics: Adenocarcinoma; Animals; Capillary Permeability; Colonic Neoplasms; Fluorescent Dyes; Mice; Mice, SCID; Microcirculation; Microscopy, Fluorescence; Neoplasm Transplantation; Nephelometry and Turbidimetry; Prostheses and Implants; Serum Albumin, Bovine; Skin; Specific Pathogen-Free Organisms; Transplantation, Heterologous; Videotape Recording; Xanthenes | 1993 |
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Xanthenes; Xanthones | 1993 |
Location of tumour cells in colon tissue by Texas red labelled pentosan polysulphate, an inhibitor of a cell surface protease.
Topics: Carboxylic Ester Hydrolases; Cell Membrane; Chromatography, Affinity; Colonic Neoplasms; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Fluorescent Dyes; Heparin; Humans; Hymecromone; Isoenzymes; Kinetics; Microscopy, Fluorescence; Pentosan Sulfuric Polyester; Protease Inhibitors; Protein Conformation; Suramin; Trypan Blue; Xanthenes | 1996 |
Increased plasma serotonin following treatment with flavone-8-acetic acid, 5,6-dimethylxanthenone-4-acetic acid, vinblastine, and colchicine: relation to vascular effects.
Topics: Animals; Antineoplastic Agents; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Serotonin; Time Factors; Vinblastine; Xanthenes; Xanthones | 1997 |
Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid: concomitant reduction of serum tumour necrosis factor-alpha and enhancement of anti-tumour activity.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Synergism; Mice; Neoplasm Transplantation; Pentoxifylline; Phthalimides; Thalidomide; Time Factors; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1998 |
Antitumour activity of the novel immune modulator 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice lacking the interferon-gamma receptor.
Topics: Animals; Colonic Neoplasms; Cyclosporine; Enzyme-Linked Immunosorbent Assay; Immunosuppressive Agents; Interferon gamma Receptor; Interferon-gamma; Lipopolysaccharides; Mice; Nitric Oxide; Receptors, Interferon; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1998 |
Thalidomide increases both intra-tumoural tumour necrosis factor-alpha production and anti-tumour activity in response to 5,6-dimethylxanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Synergism; Female; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; RNA, Messenger; Spleen; Thalidomide; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1999 |
Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Hemorrhage; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neoplasm Proteins; Neovascularization, Pathologic; RNA, Messenger; RNA, Neoplasm; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1999 |
Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer: construction and testing of a tissue-specific adenovirus vector.
Topics: Adenoviridae; Androgens; Antineoplastic Agents; Aziridines; Cell Survival; Colonic Neoplasms; Coloring Agents; Cytomegalovirus; Enhancer Elements, Genetic; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Humans; Jurkat Cells; Kinetics; Luciferases; Luminescent Proteins; Male; Oxazines; Polymerase Chain Reaction; Prodrugs; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Recombinant Fusion Proteins; Tissue Kallikreins; Transfection; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Xanthenes | 2000 |
Inhibition of cell growth in culture by quinones.
Topics: Anthraquinones; Antineoplastic Agents; Arbutin; Cell Division; Colonic Neoplasms; Humans; Naphthoquinones; Quinones; Tumor Cells, Cultured; Xanthenes; Xanthones | 1998 |
Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Bile; Colonic Neoplasms; Female; Half-Life; Mice; Mice, Inbred C57BL; Stereoisomerism; Thalidomide; Time Factors; Tissue Distribution; Xanthenes; Xanthones | 2000 |
Targeted killing of carcinoembryonic antigen (CEA)-producing cholangiocarcinoma cells by polyamidoamine dendrimer-mediated transfer of an Epstein-Barr virus (EBV)-based plasmid vector carrying the CEA promoter.
Topics: beta-Galactosidase; Carcinoembryonic Antigen; Cell Survival; Cholangiocarcinoma; Colonic Neoplasms; Coloring Agents; DNA Primers; Epstein-Barr Virus Nuclear Antigens; Ganciclovir; Genetic Therapy; Genetic Vectors; Humans; Oxazines; Polyamines; Polymerase Chain Reaction; Promoter Regions, Genetic; Transfection; Tumor Cells, Cultured; Xanthenes | 2000 |
The inhibitory effects of mangiferin, a naturally occurring glucosylxanthone, in bowel carcinogenesis of male F344 rats.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Cell Division; Colonic Neoplasms; Drug Screening Assays, Antitumor; Intestinal Mucosa; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Xanthenes; Xanthones | 2001 |
Interferon-inducible protein 10 induction and inhibition of angiogenesis in vivo by the antitumor agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
Topics: Animals; Antibodies; Antineoplastic Agents; Chemokine CCL4; Chemokine CXCL10; Chemokines, CXC; Collagen; Colonic Neoplasms; Drug Combinations; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Interferons; Interleukin-12; Laminin; Macrophage Inflammatory Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neovascularization, Physiologic; Proteoglycans; RNA, Messenger; Spleen; Up-Regulation; Xanthenes; Xanthones | 2001 |
Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyproheptadine; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Female; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Serotonin Antagonists; Tissue Distribution; Xanthenes; Xanthones | 2001 |
Dicerandrols, new antibiotic and cytotoxic dimers produced by the fungus Phomopsis longicolla isolated from an endangered mint.
Topics: Antibiotics, Antineoplastic; Ascomycota; Bacillus subtilis; Colonic Neoplasms; Florida; Geotrichum; Humans; Lamiaceae; Lung Neoplasms; Magnetic Resonance Spectroscopy; Molecular Structure; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Staphylococcus aureus; Stereoisomerism; Tumor Cells, Cultured; Xanthenes; Xanthones | 2001 |
Oral activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Half-Life; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Nitric Oxide; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 2002 |
Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4-acetic acid, assessed using MRI and MRS.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Mice, SCID; Stilbenes; Transplantation, Heterologous; Xanthenes; Xanthones | 2002 |
Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor.
Topics: Animals; Antibiotics, Antineoplastic; Antifungal Agents; Benzyl Alcohols; Breast Neoplasms; Caribbean Region; Central Nervous System Neoplasms; Colonic Neoplasms; Cyclopentanes; Drug Screening Assays, Antitumor; Ergosterol; Female; Fungi; Furans; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Kidney Neoplasms; Leukemia P388; Lung Neoplasms; Male; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Porifera; Prostatic Neoplasms; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured; Xanthenes; Xanthones | 2002 |
Modulation of superoxide production from murine macrophages by the antitumour agent flavone acetic acid and xanthenone acetic acid analogues.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Macrophages; Mice; Mice, Inbred C3H; Necrosis; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthenes | 1992 |
Structure-activity relationships for substituted 9-oxo-9,10-dihydroacridine-4-acetic acids: analogues of the colon tumour active agent xanthenone-4-acetic acid.
Topics: Animals; Colonic Neoplasms; Drug Design; Mice; Necrosis; Structure-Activity Relationship; Xanthenes | 1992 |
Cytokine induction and therapeutic synergy with interleukin-2 against murine renal and colon cancers by xanthenone-4-acetic acid derivatives.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Cytokines; DNA; DNA Probes; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Gene Expression Regulation, Neoplastic; Interferon-alpha; Interferon-gamma; Interleukin-2; Kidney Neoplasms; Leukocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Recombinant Proteins; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Xanthenes | 1992 |
Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred Strains; Mice, Nude; Necrosis; T-Lymphocytes; Thymectomy; Xanthenes; Xanthones | 1992 |
Induction of natural killer activity by xanthenone analogues of flavone acetic acid: relation with antitumour activity.
Topics: Animals; Colonic Neoplasms; Cytotoxicity, Immunologic; Dose-Response Relationship, Immunologic; Immunologic Factors; Killer Cells, Natural; Mice; Mice, Inbred Strains; Xanthenes | 1991 |
Determination of xanthenone-4-acetic acid in mouse plasma by high-performance liquid chromatography.
Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Colonic Neoplasms; Male; Mice; Xanthenes | 1991 |
Potential antitumor agents. 63. Structure-activity relationships for side-chain analogues of the colon 38 active agent 9-oxo-9H-xanthene-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Macrophages; Methylation; Mice; Nitrates; Nitrites; Structure-Activity Relationship; Xanthenes | 1991 |
Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Methylation; Mice; Mice, Inbred Strains; Nitrates; Nitrites; Xanthenes; Xanthones | 1991 |
Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Indicators and Reagents; Mice; Mice, Inbred Strains; Molecular Structure; Structure-Activity Relationship; Xanthenes; Xanthones | 1991 |
Potential antitumor agents. 62. Structure-activity relationships for tricyclic compounds related to the colon tumor active drug 9-oxo-9H-xanthene-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colonic Neoplasms; Mice; Neoplasm Transplantation; Structure-Activity Relationship; Xanthenes | 1991 |
Confocal microscopy as a tool to reveal the tridimensional organization of intracellular lumens and intercellular cysts in a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Cell Compartmentation; Cell Membrane; Colonic Neoplasms; Fluorescent Dyes; Humans; Image Processing, Computer-Assisted; Microscopy, Electron; Microscopy, Fluorescence; Microvilli; Tumor Cells, Cultured; Xanthenes | 1990 |
Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Arginine; Cell Survival; Colonic Neoplasms; Dexamethasone; Flavonoids; Macrophages; Mice; Neoplasm Transplantation; Nitrates; Nitric Acid; Nitric Oxide; omega-N-Methylarginine; Xanthenes | 1990 |
Potential antitumor agents. 60. Relationships between structure and in vivo colon 38 activity for 5-substituted 9-oxoxanthene-4-acetic acids.
Topics: Acetates; Adenocarcinoma; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colonic Neoplasms; Flavonoids; Mice; Structure-Activity Relationship; Xanthenes | 1990 |
Structural determinants of phenoxazine type compounds required to modulate the accumulation of vinblastine and vincristine in multidrug-resistant cell lines.
Topics: Adenocarcinoma; Biological Transport; Cell Line; Colonic Neoplasms; Drug Resistance; HeLa Cells; Humans; Molecular Structure; Oxazines; Structure-Activity Relationship; Verapamil; Vinblastine; Vincristine; Xanthenes | 1990 |
Absence of preferential uptake of [125I]iododihydrorhodamine 123 by four human tumor xenografts.
Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; Fibrosarcoma; Humans; Iodine Radioisotopes; Male; Mice; Mice, Nude; Pancreatic Neoplasms; Prostatic Neoplasms; Radioisotope Dilution Technique; Rhodamine 123; Rhodamines; Tissue Distribution; Transplantation, Heterologous; Xanthenes | 1989 |
Potential antitumor agents. 58. Synthesis and structure-activity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumor in vivo.
Topics: Acetates; Adenocarcinoma; Animals; Chemical Phenomena; Chemistry; Chlorine; Colonic Neoplasms; Hydroxylation; Methylation; Mice; Nitro Compounds; Structure-Activity Relationship; Xanthenes | 1989 |