Page last updated: 2024-09-03

wy 45911 and Muscle Contraction

wy 45911 has been researched along with Muscle Contraction in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bender, RH; Carlson, RP; Chang, J; Grimes, D; Hand, JM; Kreft, AF; Kubrak, DM; Musser, JH1
Chang, J; Kubrak, DM; Lewis, AJ; Musser, JH1
Chang, J; DiZio, SM; Hand, JM; Hite, M; Kubrak, DM; Lewis, AJ; Musser, JH1
Chang, J; Hand, JM; Musser, JH1

Other Studies

4 other study(ies) available for wy 45911 and Muscle Contraction

ArticleYear
N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Azoles; Benzamides; Biological Assay; Bronchial Spasm; Carrageenan; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Edema; Guinea Pigs; Hydroxamic Acids; Lipoxygenase Inhibitors; Molecular Structure; Muscle Contraction; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Tetrazoles; Trachea

1990
Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:8

    Topics: Animals; Arachidonate Lipoxygenases; Bronchi; Guinea Pigs; Lipoxygenase Inhibitors; Male; Methyl Ethers; Muscle Contraction; Naphthalenes; Neutrophils; Ovalbumin; Quinolines; Rats; SRS-A; Structure-Activity Relationship; Trachea

1986
Leukotriene D4 antagonists and 5-lipoxygenase inhibitors. Synthesis of benzoheterocyclic [(methoxyphenyl)amino]oxoalkanoic acid esters.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Fatty Acids; Guinea Pigs; Heterocyclic Compounds; Indicators and Reagents; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muscle Contraction; Muscle, Smooth; Neutrophils; Rats; Spectrophotometry, Infrared; SRS-A; Structure-Activity Relationship

1987
Effect of a novel leukotriene D4 antagonist with 5-lipoxygenase and cyclooxygenase inhibitory activity, Wy-45,911, on leukotriene-D4-and antigen-induced bronchoconstriction in the guinea pig.
    International archives of allergy and applied immunology, 1988, Volume: 86, Issue:1

    Topics: Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Asthma; Cyclooxygenase Inhibitors; Guinea Pigs; Lipoxygenase Inhibitors; Macrophages; Male; Muscle Contraction; Peritoneal Cavity; Quinolines; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Thromboxane B2; Trachea

1988