wr 99210 has been researched along with Malaria, Falciparum in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brun, R; Chitnumsub, P; Dartois, V; Diagana, TT; Goh, A; Kamchonwongpaisan, S; Keller, TH; Kiara, SM; Lakshminarayana, SB; Ma, NL; Maneeruttanarungroj, C; Nzila, A; Rottmann, M; Taweechai, S; Weaver, M; Wittlin, S; Wong, J; Yeung, BK; Yuthavong, Y; Zou, B | 1 |
| Delfino, RT; Figueroa-Villar, JD; Santos-Filho, OA | 1 |
| Ager, AL; Canfield, CJ; Jacobus, DP; Lewis, NJ; Milhous, WK; Rossan, RN; Sweeney, TR | 1 |
| Jacobus, DP; Kinyanjui, SM; Mberu, EK; Watkins, WM; Winstanley, PA | 1 |
| Howard, V; Mookherjee, S; Nzila-Mouanda, A; Sibley, CH; Watkins, W | 1 |
| Cowman, AF; Duraisingh, MT; Triglia, T | 1 |
6 other study(ies) available for wr 99210 and Malaria, Falciparum
| Article | Year |
|---|---|
Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate.
Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Drug Resistance; Female; Folic Acid Antagonists; Humans; In Vitro Techniques; Malaria; Malaria, Falciparum; Male; Mice; Models, Molecular; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinazolines; Rats; Rats, Wistar; Tetrahydrofolate Dehydrogenase | 2010 |
Molecular modeling of wild-type and antifolate resistant mutant Plasmodium falciparum DHFR.
Topics: Animals; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Liver; Malaria, Falciparum; Models, Chemical; Models, Genetic; Models, Molecular; Molecular Sequence Data; Plasmodium falciparum; Point Mutation; Proguanil; Pyrimethamine; Sequence Alignment; Tetrahydrofolate Dehydrogenase; Triazines | 2002 |
PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.
Topics: Administration, Oral; Animals; Antimalarials; Aotus trivirgatus; Atovaquone; Drug Synergism; Folic Acid Antagonists; Imides; Injections, Subcutaneous; Malaria, Falciparum; Mice; Naphthoquinones; Phenyl Ethers; Plasmodium falciparum; Proguanil; Sulfamethoxazole; Triazines | 1993 |
The antimalarial triazine WR99210 and the prodrug PS-15: folate reversal of in vitro activity against Plasmodium falciparum and a non-antifolate mode of action of the prodrug.
Topics: Animals; Antidotes; Antimalarials; Asia, Southeastern; Dose-Response Relationship, Drug; Drug Resistance; Folic Acid; Folic Acid Antagonists; Hematinics; Humans; Inhibitory Concentration 50; Kenya; Leucovorin; Malaria, Falciparum; Plasmodium falciparum; Prodrugs; Proguanil; Triazines | 1999 |
Identification and analysis of dihydrofolate reductase alleles from Plasmodium falciparum present at low frequency in polyclonal patient samples.
Topics: Alleles; Animals; Antimalarials; DNA Primers; DNA Restriction Enzymes; DNA, Protozoan; Humans; Inhibitory Concentration 50; Kenya; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Proguanil; Pyrimethamine; Saccharomyces cerevisiae; Tetrahydrofolate Dehydrogenase; Triazines | 1999 |
Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination.
Topics: Animals; Antimalarials; Antimetabolites; Antiviral Agents; Blotting, Southern; Cytosine Deaminase; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; Flucytosine; Ganciclovir; Gene Deletion; Malaria, Falciparum; Nucleoside Deaminases; Plasmids; Plasmodium falciparum; Recombination, Genetic; Thymidine Kinase; Triazines | 2002 |