Compounds > win 18446
Page last updated: 2024-08-21

win 18446 and Pregnancy

win 18446 has been researched along with Pregnancy in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Baek, SK; Jeong, JS; Kim, SY; Kim, W; Lee, J; Lee, SJ; Lee, SY; Nam, SY; Oh, JH; Park, D; Park, JD; Quah, Y; Yu, WJ1
Deprest, J; Jimenez, J; Müller, C; Nguyen, TM; Rendin, LE; Toelen, J; Westergren-Thorsson, G1
Brooks, NL; van der Horst, G1
Fujino, H; Hanato, T; Kise, K; Nakagawa, M; Nishijima, S; Okamoto, N; Shiraishi, I; Takeuchi, Y; Watanabe, N1
Hess, RA; Kilburn, KH; Lesser, M; Oster, G1
Kilburn, KH; Oster, G; Siegal, FP1
Fujino, H; Hanato, T; Nakagawa, M; Nishijima, S; Okamoto, N; Shimada, M1
Ando, M; Ito, T; Momma, K; Mori, Y1
Bockman, DE; Kuratani, SC1
Hamada, M; Koga, Y; Okamoto, N; Onitsuka, T; Takenaka, H; Tasaka, H1
Porter, JF; Schmidt, RR1

Other Studies

11 other study(ies) available for win 18446 and Pregnancy

ArticleYear
Bis-diamine administration during pregnancy induces developmental and reproductive toxicities in rats.
    Birth defects research, 2022, 07-01, Volume: 114, Issue:11

    Topics: Animals; Diamines; Disease Models, Animal; Female; Heart; Heart Defects, Congenital; Male; Pregnancy; Rats; Reproduction

2022
The proportion of alveolar type 1 cells decreases in murine hypoplastic congenital diaphragmatic hernia lungs.
    PloS one, 2019, Volume: 14, Issue:4

    Topics: Alveolar Epithelial Cells; Animals; Cell Count; Cell Differentiation; Diamines; Disease Models, Animal; Embryonic Stem Cells; Female; Hernias, Diaphragmatic, Congenital; Lung; Mice; Organ Size; Phenyl Ethers; Pregnancy; Teratogens

2019
Short-term effects of N'N-bis(dichloroacetyl)-1,8-octamethylenediamine (WIN 18446) on the testes, selected sperm parameters and fertility of male CBA mice.
    Laboratory animals, 2003, Volume: 37, Issue:4

    Topics: Animals; Contraceptive Agents, Male; Diamines; Female; Fertility; Leydig Cells; Male; Mice; Mice, Inbred CBA; Microscopy, Electron, Scanning; Pregnancy; Seminiferous Tubules; Sperm Count; Sperm Motility; Spermatogenesis; Spermatozoa; Testis

2003
Teratogenic effects of bis-diamine on the developing cardiac conduction system.
    Birth defects research. Part A, Clinical and molecular teratology, 2005, Volume: 73, Issue:8

    Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; CD57 Antigens; Diamines; Female; Fibroblasts; Gap Junctions; Heart Conduction System; Heart Defects, Congenital; Heart Septum; Muscle Proteins; Myocardium; Pregnancy; Rats; Rats, Wistar; Teratogens

2005
Perinatal death and respiratory apparatus dysgenesis due to a bis (dichloroacetyl) diamine.
    Teratology, 1982, Volume: 26, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Diamines; Dose-Response Relationship, Drug; Female; Fetal Death; Lung; Pregnancy; Rats; Rats, Inbred Strains; Respiratory System Abnormalities; Spermatogenesis-Blocking Agents

1982
Chemically induced congenital thymic dysgenesis in the rat: a model of the DiGeorge syndrome.
    Clinical immunology and immunopathology, 1983, Volume: 28, Issue:1

    Topics: Animals; Diamines; DiGeorge Syndrome; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Immunologic Deficiency Syndromes; Pregnancy; Rats; Thymus Gland; Time Factors

1983
Teratogenic effects of bis-diamine on early embryonic rat heart: an in vitro study.
    Teratology, 2000, Volume: 62, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Cell Movement; Diamines; Female; Heart; Immunohistochemistry; Maternal-Fetal Exchange; Myocardium; Neural Cell Adhesion Molecules; Neural Crest; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Spermatogenesis-Blocking Agents; Teratogens; Time Factors

2000
Hypoplasia of the lung and heart in fetal rats with diaphragmatic hernia.
    Fetal diagnosis and therapy, 1992, Volume: 7, Issue:1

    Topics: Abnormalities, Multiple; Animals; Diamines; Disease Models, Animal; Female; Fetal Diseases; Heart Defects, Congenital; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lung; Pregnancy; Rats; Rats, Inbred Strains; Teratogens

1992
Inhibition of epibranchial placode-derived ganglia in the developing rat by bisdiamine.
    The Anatomical record, 1992, Volume: 233, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Diamines; Female; Immunohistochemistry; Nervous System; Nodose Ganglion; Pharynx; Pregnancy; Rats; Rats, Inbred Strains; Vagus Nerve

1992
Abnormal development of cardiovascular systems in rat embryos treated with bisdiamine.
    Teratology, 1991, Volume: 43, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Aorta, Thoracic; Cardiovascular System; Diamines; Dose-Response Relationship, Drug; Female; Heart Defects, Congenital; Male; Pregnancy; Pulmonary Artery; Rats; Rats, Inbred Strains

1991
Developmental toxicity of N,N1-bis(dichloroacetyl)-1,8-octamethylene diamine: effects of in utero exposure on the postnatal murine immune system.
    Biology of the neonate, 1986, Volume: 50, Issue:4

    Topics: Abnormalities, Drug-Induced; Aging; Animals; Diamines; Female; Gestational Age; Immunologic Deficiency Syndromes; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Phytohemagglutinins; Pokeweed Mitogens; Pregnancy; Spleen; Thymus Gland

1986