web 2086 has been researched along with Shock, Septic in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 11 (73.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Endres, S; Kohl, J; Machleidt, W; Siebeck, M; Spannagl, M | 1 |
| Bachy, A; Fraisse, L; Herbert, JM; Keane, PE; Lale, A; Laplace, MC; Lassalle, J; Roche, B; Savi, P; Valette, G | 1 |
| De Kimpe, SJ; Thiemermann, C; Vane, JR | 1 |
| Balsa, D; Ferrando, R; Forn, J; Garcia-Rafanell, J; Giral, M; Merlos, M | 1 |
| Quinn, JV; Slotman, GJ | 1 |
| Araújo, CV; Barbosa-Filho, JM; Cordeiro, RS; Tibiriçá, E | 1 |
| Imura, Y; Kawamura, M; Nishikawa, K; Takatani, M; Terashita, Z; Tsushima, S | 1 |
| Herbert, JM; Lespy, L; Maffrand, JP | 1 |
| Heuer, HO | 1 |
| Keser, C; Kohl, J; Machleidt, W; Schweiberer, L; Siebeck, M; Spannagl, M; Weipert, J | 1 |
| Heuer, HO; Letts, G; Meade, CJ | 1 |
| Jones, SB; Qi, M | 1 |
| Casals-Stenzel, J; Heuer, H | 1 |
| Bahrami, S; Paul, E; Redl, H; Schiesser, A; Schlag, G; Thurnher, M; Vogl, C | 1 |
| Casals-Stenzel, J | 1 |
1 review(s) available for web 2086 and Shock, Septic
| Article | Year |
|---|---|
Involvement of platelet-activating factor (PAF) in septic shock and priming as indicated by the effect of hetrazepinoic PAF antagonists.
Topics: Animals; Azepines; Endotoxins; Humans; Models, Biological; Multiple Organ Failure; Platelet Activating Factor; Shock, Septic; Triazoles | 1991 |
14 other study(ies) available for web 2086 and Shock, Septic
| Article | Year |
|---|---|
Delayed treatment with platelet activating factor receptor antagonist web 2086 attenuates pulmonary dysfunction in porcine endotoxin shock.
Topics: Animals; Azepines; Blood Pressure; Cathepsin B; Creatinine; Extravascular Lung Water; Hypertension, Pulmonary; Lipopolysaccharides; Lung; Platelet Activating Factor; Pulmonary Artery; Pulmonary Gas Exchange; Salmonella; Shock, Septic; Swine; Swine, Miniature; Triazoles; Tumor Necrosis Factor-alpha; Vascular Resistance | 1994 |
Biochemical and pharmacological properties of SR 27388, a dual antioxidant and PAF receptor antagonist.
Topics: Animals; Antioxidants; Azepines; Blood Glucose; Blood Platelets; Cattle; Diabetes Mellitus, Experimental; Free Radical Scavengers; Humans; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; Mitochondria, Heart; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Superoxides; Sympathomimetics; Thiazoles; Thiobarbituric Acid Reactive Substances; Triazoles | 1993 |
Role for intracellular platelet-activating factor in the circulatory failure in a model of gram-positive shock.
Topics: Acute Kidney Injury; Animals; Azepines; Cells, Cultured; Diterpenes; Ginkgolides; Hemodynamics; Lactones; Lipopolysaccharides; Lung; Male; Nitric Oxide Synthase; Nitrites; Norepinephrine; Plant Extracts; Platelet Activating Factor; Rats; Rats, Wistar; Shock, Septic; Streptomyces; Teichoic Acids; Triazoles; Tumor Necrosis Factor-alpha | 1995 |
Effects of UR-12633, a new antagonist of platelet-activating factor, in rodent models of endotoxic shock.
Topics: Analysis of Variance; Animals; Azepines; Blood Pressure; Cell Membrane; Disease Models, Animal; Escherichia coli; Hypotension; Lipopolysaccharides; Male; Mice; Piperidines; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Shock, Septic; Triazoles | 1996 |
Platelet-activating factor and arachidonic acid metabolites mediate tumor necrosis factor and eicosanoid kinetics and cardiopulmonary dysfunction during bacteremic shock.
Topics: Aeromonas hydrophila; Animals; Arachidonic Acid; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Eicosanoids; Female; Gram-Negative Bacterial Infections; Heart Diseases; Hemodynamics; Hypertension, Pulmonary; Lipoxygenase Inhibitors; Masoprocol; Oxazoles; Oxygen; Oxygen Consumption; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Shock, Septic; Swine; Thromboxane A2; Triazoles; Tumor Necrosis Factor-alpha | 1999 |
Protective effects of yangambin on cardiovascular hyporeactivity to catecholamines in rats with endotoxin-induced shock.
Topics: Animals; Azepines; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Drug Interactions; Furans; Heart Rate; Lignans; Lipopolysaccharides; Male; Norepinephrine; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Cardiogenic; Shock, Septic; Triazoles; Vasoconstrictor Agents | 2001 |
Beneficial effects of TCV-309, a novel potent and selective platelet activating factor antagonist in endotoxin and anaphylactic shock in rodents.
Topics: Anaphylaxis; Animals; Azepines; Furans; Hemolysis; Humans; Hypotension; Isoquinolines; Male; Microsomes; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Shock, Septic; Tetrahydroisoquinolines; Triazoles | 1992 |
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
Topics: Anaphylaxis; Animals; Azepines; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Male; Mice; Mice, Inbred Strains; Ovalbumin; Platelet Activating Factor; Shock, Septic; Thiazoles; Triazoles | 1991 |
A triazolodiazepine platelet activating factor receptor antagonist (WEB 2086) reduces pulmonary dysfunction during endotoxin shock in swine.
Topics: Animals; Azepines; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Endotoxins; Leukocyte Count; Lung; Platelet Activating Factor; Pulmonary Artery; Pulmonary Circulation; Pulmonary Gas Exchange; Salmonella; Shock, Septic; Swine; Swine, Miniature; Tissue Plasminogen Activator; Triazoles; Vascular Resistance | 1991 |
Tumor necrosis factor (TNF) and endotoxin prime effects of PAF in vivo.
Topics: Animals; Azepines; Drug Interactions; Endotoxins; Gastrointestinal Transit; Mice; Platelet Activating Factor; Shock, Septic; Triazoles; Tumor Necrosis Factor-alpha | 1990 |
Contribution of platelet activating factor to hemodynamic and sympathetic responses to bacterial endotoxin in conscious rats.
Topics: Animals; Azepines; Blood Glucose; Blood Pressure; Catecholamines; Endotoxins; Heart Rate; Hemodynamics; Lactates; Lactic Acid; Male; Platelet Activating Factor; Rats; Shock, Septic; Sympathetic Nervous System; Triazoles | 1990 |
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guinea Pigs; Lung Diseases; Ovalbumin; Platelet Activating Factor; Pyrilamine; Shock, Septic; Triazines; Triazoles | 1989 |
Effect of PAF-antagonists in endotoxin shock--ovine and rat experiments.
Topics: Animals; Azepines; Blood Pressure; Diterpenes; Ginkgolides; Hemodynamics; Kinetics; Lactones; Lymph; Male; Platelet Activating Factor; Proteins; Pulmonary Artery; Rats; Rats, Inbred Strains; Sheep; Shock, Septic; Triazines; Triazoles | 1989 |
Protective effect of WEB 2086, a novel antagonist of platelet activating factor, in endotoxin shock.
Topics: Animals; Azepines; Blood Pressure; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Triazines; Triazoles | 1987 |