Page last updated: 2024-08-24

web 2086 and Disease Models, Animal

web 2086 has been researched along with Disease Models, Animal in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's14 (60.87)18.2507
2000's4 (17.39)29.6817
2010's2 (8.70)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Ishibashi, T; Oshima, Y; Sonoda, KH; Takeda, A; Yang, Y; Yoshimura, T; Zhang, H1
Bessi, VL; Bitencourt, CS; Borgeat, P; Faccioli, LH; Hamdan, L; Huynh, DN; Lefebvre, JS; Lévesque, T; Marleau, S; Ménard, L; Sohouhenou, F1
Bloechle, C; Izbicki, JR; Kaifi, J; Kluth, D; Mann, O; Schneider, C; Strate, T; Tiefenbacher, WJ; Yekebas, E1
Kato, M; Kurose, T; Miyaji, S; Oda, T1
Cepinskas, G; Handa, O; Kvietys, PR; Madorin, WS; Rui, T; Sugimoto, N1
Langer, JC; Liebman, SM; Monk, PK; Pelletier, GJ1
Lopez-Belmonte, J; Whittle, BJ1
Dosen, P; Gerkens, JF; Smith, AJ1
Kakuta, S1
Aguirre, B; Alvarez, T; Fernandez, L; González-Fajardo, JA; Ramos, G; Vaquero, C1
Balsa, D; Ferrando, R; Forn, J; Garcia-Rafanell, J; Giral, M; Merlos, M1
Chen, J; Giri, SN; Ziboh, V1
Berend, N; Matheson, MJ; McClean, MA; Rynell, AC1
Backer, CL; Crawford, SE; Gonzalez-Crussi, F; Hsueh, W; Huang, L; Liu, H; Mavroudis, C; Mu, Y; Takami, H1
Cheung, LY; Childs, EW; Miller, JL; Moncure, M; Smalley, DM1
Leong, LL; Stephens, CJ; Sturm, MJ; Taylor, RR1
Alison, MR; Antoniw, JW; Garvey, B; Maseri, A; Tippins, JR1
Horie, M; Mase, T; Nagaoka, H; Sakurai, Y; Tomioka, K; Yamada, T1
Arima, M; Makino, S; Sagara, H; Terashi, Y; Yukawa, T1
Barnes, PJ; Evans, TW; McCormack, DG1
Casals-Stenzel, J; Heuer, H1
Abraham, WM; Garrido, R; Stevenson, JS1

Other Studies

23 other study(ies) available for web 2086 and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
A Novel Platelet-Activating Factor Receptor Antagonist Inhibits Choroidal Neovascularization and Subretinal Fibrosis.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Animals; Azepines; Choroidal Neovascularization; Disease Models, Animal; Female; Fibrosis; Hematologic Agents; Lasers; Macrophages; Mice, Inbred C57BL; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Retinal Diseases; RNA, Messenger; Triazoles

2013
Cooperative role of endogenous leucotrienes and platelet-activating factor in ischaemia-reperfusion-mediated tissue injury.
    Journal of cellular and molecular medicine, 2013, Volume: 17, Issue:12

    Topics: Amidines; Animals; Azepines; Biological Assay; Carbamates; Dermis; Disease Models, Animal; Extravasation of Diagnostic and Therapeutic Materials; Extremities; Inflammation; Leukotriene B4; Leukotrienes; Male; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Neutrophil Infiltration; Platelet Activating Factor; Platelet Membrane Glycoproteins; Propionates; Quinolines; Rabbits; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Reperfusion Injury; Triazoles

2013
Effect of platelet-activating factor antagonist WEB 2086 on microcirculatory disorders in acute experimental pancreatitis of graded severity.
    Pancreas, 2009, Volume: 38, Issue:1

    Topics: Amylases; Animals; Azepines; Capillaries; Cell Adhesion; Ceruletide; Disease Models, Animal; Edema; Female; Glycodeoxycholic Acid; Leukocytes; Microcirculation; Oligopeptides; Pancreas; Pancreatitis; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Severity of Illness Index; Taurocholic Acid; Time Factors; Triazoles

2009
The role of platelet activating factor and the efficacy of apafant ophthalmic solution in experimental allergic conjunctivitis.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:4

    Topics: Animals; Antigens; Azepines; Capillary Permeability; Conjunctivitis, Allergic; Disease Models, Animal; Dose-Response Relationship, Drug; Dye Dilution Technique; Guinea Pigs; Humans; Immunization, Passive; Ketotifen; Male; Ophthalmic Solutions; Platelet Activating Factor; Pruritus; Time Factors; Triazoles

2003
Cardiac myocytes activated by septic plasma promote neutrophil transendothelial migration: role of platelet-activating factor and the chemokines LIX and KC.
    Circulation research, 2004, Apr-16, Volume: 94, Issue:7

    Topics: Animals; Animals, Newborn; Azepines; Cecum; Chemokine CXCL1; Chemokine CXCL5; Chemokines, CXC; Chemotaxis, Leukocyte; Cysteine Endopeptidases; Disease Models, Animal; Endothelium, Vascular; Intercellular Signaling Peptides and Proteins; Interleukin-1; Intestinal Perforation; Leupeptins; Ligation; Mice; Mice, Inbred C57BL; Mice, Knockout; Multienzyme Complexes; Myocytes, Cardiac; Neutrophils; NF-kappa B; Peritonitis; Plasma; Protease Inhibitors; Proteasome Endopeptidase Complex; Sepsis; Triazoles; Tumor Necrosis Factor-alpha

2004
Mast cell mediators and peritoneal adhesion formation in the rat.
    The Journal of surgical research, 1995, Volume: 59, Issue:3

    Topics: Animals; Azepines; Disease Models, Animal; Histamine Antagonists; Leukotriene D4; Male; Mast Cells; Methysergide; Ondansetron; Peritoneal Diseases; Platelet Activating Factor; Propionates; Pyrilamine; Quinolines; Ranitidine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tissue Adhesions; Triazoles

1995
Endothelin-1 induces neutrophil-independent vascular injury in the rat gastric microcirculation.
    European journal of pharmacology, 1995, May-04, Volume: 278, Issue:1

    Topics: Animals; Azepines; Capillary Permeability; Disease Models, Animal; Endothelins; Endothelium, Vascular; Gastric Mucosa; Infusions, Intra-Arterial; Isotope Labeling; Male; Methacrylates; Neutrophils; Platelet Activating Factor; Rats; Rats, Wistar; Serum Albumin; Stomach Ulcer; Thromboxane-A Synthase; Triazoles

1995
WEB-2086 and indomethacin do not modify blood pressure fall on unclipping hypertensive rats.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:5

    Topics: Animals; Azepines; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Indomethacin; Injections, Intravenous; Male; Platelet Activating Factor; Rats; Rats, Wistar; Renal Artery; Triazoles

1994
[Effects of reactive oxygen species scavenger and platelet activating factor receptor antagonist on accelerated nephrotoxic nephritis].
    Nihon Jinzo Gakkai shi, 1993, Volume: 35, Issue:2

    Topics: Animals; Azepines; Disease Models, Animal; Ferric Compounds; Free Radical Scavengers; Glomerulonephritis; Luminescent Measurements; Male; Platelet Aggregation Inhibitors; Pyridines; Rabbits; Rats; Rats, Wistar; Reactive Oxygen Species; Triazoles

1993
Protective effect of a platelet-activating factor antagonist (WEB-2086) in postischemic renal failure.
    Annals of vascular surgery, 1996, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Animals; Azepines; Disease Models, Animal; Diuresis; Female; Ischemia; Kidney; Kidney Function Tests; Male; Necrosis; Platelet Activating Factor; Platelet Aggregation Inhibitors; Rabbits; Triazoles

1996
Effects of UR-12633, a new antagonist of platelet-activating factor, in rodent models of endotoxic shock.
    British journal of pharmacology, 1996, Volume: 118, Issue:5

    Topics: Analysis of Variance; Animals; Azepines; Blood Pressure; Cell Membrane; Disease Models, Animal; Escherichia coli; Hypotension; Lipopolysaccharides; Male; Mice; Piperidines; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Shock, Septic; Triazoles

1996
Up-regulation of platelet-activating factor receptors in lung and alveolar macrophages in the bleomycin-hamster model of pulmonary fibrosis.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:3

    Topics: Animals; Azepines; Bleomycin; Cricetinae; Disease Models, Animal; Lung; Macrophages, Alveolar; Male; Mesocricetus; Platelet Membrane Glycoproteins; Protein Binding; Pulmonary Fibrosis; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles; Up-Regulation

1997
Role of platelet activating factor, leukotrienes and polymorphs in the FMLP induced increase in microvascular leakage in rabbit trachea.
    Respirology (Carlton, Vic.), 1997, Volume: 2, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkylating Agents; Animals; Azepines; Bronchitis; Capillary Permeability; Coloring Agents; Disease Models, Animal; Drug Interactions; Evans Blue; Indazoles; Leukotrienes; Male; Mechlorethamine; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rabbits; Reference Values; Trachea; Triazoles; Vasoconstrictor Agents

1997
Captopril and platelet-activating factor (PAF) antagonist prevent cardiac allograft vasculopathy in rats: role of endogenous PAF and PAF-like compounds.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Azepines; Captopril; Coronary Disease; Disease Models, Animal; Drug Therapy, Combination; Heart Transplantation; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Random Allocation; Rats; Rats, Inbred F344; Rats, Inbred Lew; Transplantation, Homologous; Treatment Outcome; Triazoles; Ventricular Remodeling

1999
Effect of WEB 2086 on leukocyte adherence in response to hemorrhagic shock in rats.
    The Journal of trauma, 2000, Volume: 49, Issue:6

    Topics: Animals; Azepines; Cell Adhesion; Disease Models, Animal; Leukocytes; Male; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Triazoles

2000
Effect of WEB 2086 on myocardial infarct size and regional blood flow in the dog.
    Cardiovascular research, 1992, Volume: 26, Issue:2

    Topics: Animals; Azepines; Cardiac Output; Coronary Disease; Disease Models, Animal; Dogs; Myocardial Infarction; Myocardium; Platelet Activating Factor; Regional Blood Flow; Triazoles

1992
WEB 2086 inhibits neutrophil dependent increases in coronary resistance in blood perfused rabbit heart.
    Cardiovascular research, 1992, Volume: 26, Issue:2

    Topics: Animals; Azepines; Disease Models, Animal; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Triazoles; Vascular Resistance

1992
Effects of YM264, a novel PAF antagonist, on puromycin aminonucleoside-induced nephropathy in the rat.
    Biochemical and biophysical research communications, 1991, Apr-30, Volume: 176, Issue:2

    Topics: Animals; Azepines; Disease Models, Animal; Glomerulonephritis, Membranous; Hypercholesterolemia; Male; Metabolic Clearance Rate; Methylprednisolone; Piperazines; Platelet Activating Factor; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Ticlopidine; Triazoles

1991
[Involvement of platelet activating factor (PAF) in ovalbumin antigen-induced late asthmatic response and increase of airway hyperresponsiveness in a guinea pig experimental model of asthma].
    Arerugi = [Allergy], 1991, Volume: 40, Issue:2

    Topics: Airway Resistance; Animals; Asthma; Azepines; Disease Models, Animal; Guinea Pigs; Hypersensitivity, Delayed; Male; Ovalbumin; Platelet Activating Factor; Triazoles

1991
Platelet-activating factor: evidence against a role in hypoxic pulmonary vasoconstriction.
    Critical care medicine, 1990, Volume: 18, Issue:12

    Topics: Animals; Azepines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Injections, Intravenous; Male; Platelet Activating Factor; Pulmonary Circulation; Swine; Triazoles; Vascular Resistance; Vasoconstriction

1990
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guinea Pigs; Lung Diseases; Ovalbumin; Platelet Activating Factor; Pyrilamine; Shock, Septic; Triazines; Triazoles

1989
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:5

    Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles

1989