web 2086 has been researched along with Asthma in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 15 (88.24) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hagiwara, K; Kanazawa, M; Kikuchi, I; Kikuchi, S; Kobayashi, T; Nagata, M; Sakamoto, Y | 1 |
| Calverley, PM; Dhillon, P; Higgins, C; Holgate, ST; Johnston, SL; Ramhamadany, E; Spence, DP; Turner, S; Winning, A; Winter, J | 1 |
| Barnes, PJ; Chung, KF; Elwood, W; Sakamoto, T | 1 |
| Eastwood, C; Freitag, A; Matsos, G; O'Byrne, PM; Watson, RM | 1 |
| Fukuda, T; Makino, S; Sagara, H | 1 |
| Iwahisa, Y; Kagoshima, M; Kawakami, Y; Terasawa, M; Tomomatsu, N; Yamaguchi, S | 1 |
| Itoh, K; Makino, S; Miyamoto, T; Mue, S; Nakajima, S; Shida, T; Takishima, T; Tamura, G | 1 |
| Kagoshima, M; Kohge, S; Terasawa, M; Yamaguchi, S | 1 |
| Bewtra, AK; Hopp, RJ; Miyagawa, H; Nabe, M; Okada, C; Townley, G | 1 |
| Busse, WW; Sedgwick, JB; Vrtis, RR; Zoratti, EM | 1 |
| Heuer, HO | 1 |
| Barnes, PJ; Chung, KF | 1 |
| Goldie, RG; Paterson, JW; Pedersen, KE; Rigby, PJ | 1 |
| Heuer, H; Meade, CJ | 1 |
| Arima, M; Makino, S; Sagara, H; Terashi, Y; Yukawa, T | 1 |
| Egan, RW; Fernandez, X; Gulbenkian, AR; Kreutner, W; Kung, T; Minnicozzi, M; Watnick, AS | 1 |
| Abraham, WM; Garrido, R; Stevenson, JS | 1 |
4 review(s) available for web 2086 and Asthma
| Article | Year |
|---|---|
[PAF receptor antagonist in asthma therapy].
Topics: Animals; Asthma; Azepines; Humans; Platelet Activating Factor; Triazoles | 1996 |
The effects of hetrazepine PAF antagonists in preclinical models of asthma.
Topics: Anaphylaxis; Animals; Antigens; Asthma; Azepines; Blood Platelets; Bronchi; Bronchoconstriction; Capillary Permeability; Cell Movement; Eosinophils; Lung; Platelet Activating Factor; Respiratory Hypersensitivity; Triazoles | 1991 |
Role for platelet-activating factor in asthma.
Topics: Animals; Asthma; Azepines; Eosinophils; Humans; Muscle, Smooth; Platelet Activating Factor; Respiratory Physiological Phenomena; Respiratory System; Triazoles | 1991 |
PAF antagonism as an approach to the treatment of airway hyperreactivity.
Topics: Allergens; Animals; Asthma; Azepines; Bronchoconstriction; Diterpenes; Ginkgolides; Humans; Lactones; Platelet Activating Factor; Triazoles | 1991 |
3 trial(s) available for web 2086 and Asthma
| Article | Year |
|---|---|
The effect of the orally active platelet-activating factor antagonist WEB 2086 in the treatment of asthma.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Albuterol; Asthma; Azepines; Beclomethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peak Expiratory Flow Rate; Platelet Activating Factor; Triazoles | 1994 |
Effect of a platelet activating factor antagonist, WEB 2086, on allergen induced asthmatic responses.
Topics: Administration, Oral; Adult; Asthma; Azepines; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Platelet Activating Factor; Respiratory Hypersensitivity; Time Factors; Triazoles | 1993 |
Effect of a potent platelet-activating factor antagonist, WEB-2086, on asthma. A multicenter, double-blind placebo-controlled study in Japan.
Topics: Adolescent; Adult; Aged; Anti-Asthmatic Agents; Asthma; Azepines; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Activating Factor; Treatment Outcome; Triazoles | 1996 |
10 other study(ies) available for web 2086 and Asthma
| Article | Year |
|---|---|
Eosinophil trans-basement membrane migration induced by interleukin-8 and neutrophils.
Topics: Adult; Antibodies, Monoclonal; Asthma; Azepines; Basement Membrane; Chemotaxis, Leukocyte; Coculture Techniques; Collagen; Culture Media, Conditioned; Drug Combinations; Eosinophils; Humans; Interleukin-8; Laminin; Leukotriene B4; Matrix Metalloproteinase 9; Neutrophil Activation; Neutrophils; Paracrine Communication; Platelet Activating Factor; Protease Inhibitors; Proteoglycans; Pulmonary Eosinophilia; Triazoles; Tumor Necrosis Factor-alpha | 2006 |
Role of cyclooxygenase and 5-lipoxygenase metabolites, platelet-activating factor and 5-hydroxytryptamine in allergen-induced airway responses in the brown Norway rat.
Topics: Allergens; Animals; Arachidonate 5-Lipoxygenase; Asthma; Azepines; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Hypersensitivity, Immediate; Male; Methysergide; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred BN; Serotonin; Triazoles | 1994 |
Effects of Y-24180, a long-acting and potent antagonist to platelet-activating factor, on immediate asthmatic response in guinea pigs.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Azepines; Benzoquinones; Bronchodilator Agents; Chromones; Drug Interactions; Drug Therapy, Combination; Guinea Pigs; Heptanoic Acids; Male; Methacrylates; Platelet Activating Factor; Theophylline; Triazoles | 1997 |
Suppressive effects of Y-24180, a long-acting antagonist for platelet-activating factor, on allergic pulmonary eosinophilia in mice.
Topics: Animals; Anti-Inflammatory Agents; Asthma; Azepines; Bronchoalveolar Lavage Fluid; Eosinophils; Interleukin-5; Lung; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation Inhibitors; Prednisolone; Pulmonary Eosinophilia; Triazoles | 1997 |
The effect of WEB 2086 on PAF-induced eosinophil chemotaxis and LTC4 production from eosinophils.
Topics: Adult; Asthma; Azepines; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Eosinophils; Female; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; SRS-A; Triazoles | 1992 |
The effect of platelet-activating factor on the generation of superoxide anion in human eosinophils and neutrophils.
Topics: Adult; Asthma; Azepines; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Eosinophils; Female; Fluorescent Dyes; Humans; Male; Middle Aged; Neutrophils; Platelet Activating Factor; Rhinitis; Superoxides; Triazoles | 1991 |
PAF receptors in guinea-pig and human lung.
Topics: Animals; Asthma; Autoradiography; Azepines; Bronchi; Guinea Pigs; Humans; In Vitro Techniques; Lung; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reference Values; Tissue Distribution; Trachea; Triazoles | 1990 |
[Involvement of platelet activating factor (PAF) in ovalbumin antigen-induced late asthmatic response and increase of airway hyperresponsiveness in a guinea pig experimental model of asthma].
Topics: Airway Resistance; Animals; Asthma; Azepines; Disease Models, Animal; Guinea Pigs; Hypersensitivity, Delayed; Male; Ovalbumin; Platelet Activating Factor; Triazoles | 1991 |
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Histamine; Immunization; Indomethacin; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung; Male; Naphthyridines; Ovalbumin; Platelet Activating Factor; Pyrazoles; Thromboxanes; Triazoles | 1990 |
A possible role for PAF in allergen-induced late responses: modification by a selective antagonist.
Topics: Aerosols; Allergens; Animals; Antigens, Helminth; Ascaris; Asthma; Azepines; Chlorpheniramine; Chromones; Disease Models, Animal; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Indomethacin; Lung; Platelet Activating Factor; Reference Values; Sheep; SRS-A; Triazines; Triazoles | 1989 |