Page last updated: 2024-08-24

web 2086 and Anaphylaxis

web 2086 has been researched along with Anaphylaxis in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's16 (76.19)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Almansa, C; Bartrolí, J; Carceller, E; Forn, J; García-Rafanell, J; Giral, M; Merlos, M1
Dahlén, SE; Jonsson, EW1
Halonen, M; Lohman, IC1
Ibbotson, G; Kubes, P; Scott, RB; Withers, GD1
Porsius, AJ; Vleeming, W; Wemer, J1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Lima, MC; Martins, MA; Silva, AR; Silva, PM; Vargaftig, BB1
Fisher, RA; Hines, KL1
Befus, AD; Davison, JS; Mathison, R1
Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M1
Imura, Y; Kawamura, M; Nishikawa, K; Takatani, M; Terashita, Z; Tsushima, S1
Catto-Smith, AG; Gall, DG; MacNaughton, WK1
Heuer, HO1
Herbert, JM; Lespy, L; Maffrand, JP1
Egan, RW; Fernandez, X; Gulbenkian, AR; Kreutner, W; Kung, T; Minnicozzi, M; Watnick, AS1
Desquand, S; Dumarey, C; Lefort, J; Vargaftig, BB1
Halonen, M; Lohman, I1
Piper, PJ; Yaacob, HB1
Casals-Stenzel, J; Heuer, H2
Casals-Stenzel, J1
Lefort, J; Malanchère, E; Pretolani, M; Vargaftig, BB1

Reviews

1 review(s) available for web 2086 and Anaphylaxis

ArticleYear
The effects of hetrazepine PAF antagonists in preclinical models of asthma.
    Agents and actions. Supplements, 1991, Volume: 34

    Topics: Anaphylaxis; Animals; Antigens; Asthma; Azepines; Blood Platelets; Bronchi; Bronchoconstriction; Capillary Permeability; Cell Movement; Eosinophils; Lung; Platelet Activating Factor; Respiratory Hypersensitivity; Triazoles

1991

Other Studies

20 other study(ies) available for web 2086 and Anaphylaxis

ArticleYear
Synthesis and structure-activity relationships of 1-acyl-4-((2-methyl-3-pyridyl)cyanomethyl)piperazines as PAF antagonists.
    Journal of medicinal chemistry, 1993, Oct-01, Volume: 36, Issue:20

    Topics: Anaphylaxis; Animals; Blood Pressure; Endotoxins; Escherichia coli; Male; Mice; Molecular Structure; Piperazines; Platelet Activating Factor; Platelet Aggregation; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1993
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lung; Male; Muscle Contraction; Ovalbumin; Platelet Activating Factor; Quinolines; Triazoles

1994
The effects of combined histamine and platelet-activating factor antagonism on systemic anaphylaxis induced by immunoglobulin E in the rabbit.
    The American review of respiratory disease, 1993, Volume: 147, Issue:5

    Topics: Airway Resistance; Anaphylaxis; Animals; Azepines; Basophil Degranulation Test; Blood Pressure; Chlorpheniramine; Cimetidine; Histamine; Immunoglobulin E; Leukocyte Count; Lung Compliance; Platelet Activating Factor; Rabbits; Serotonin; Tidal Volume; Triazoles

1993
Anaphylaxis-induced mesenteric vascular permeability, granulocyte adhesion, and platelet aggregates in rat.
    The American journal of physiology, 1998, Volume: 275, Issue:1

    Topics: Albuterol; Anaphylaxis; Animals; Azepines; Capillary Permeability; Cell Adhesion; Diphenhydramine; Granulocytes; Immunoglobulin E; Indomethacin; Mast Cells; Methysergide; Microscopy, Video; Ovalbumin; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Serum Albumin, Bovine; Splanchnic Circulation; Time Factors; Triazoles; Venules

1998
Modulation of antigen- and ischemia-induced effects by the platelet-activating factor antagonist WEB-2086 in isolated sensitized rat hearts.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:5

    Topics: Anaphylaxis; Animals; Antigens; Azepines; Chromatography, High Pressure Liquid; Chromones; Coronary Circulation; Heart; Histamine Release; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Platelet Activating Factor; Pressure; Rats; Rats, Wistar; Triazoles

1992
Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Dihydropyridines; Dose-Response Relationship, Drug; Hematocrit; Histamine H1 Antagonists; Leukocyte Count; Male; Meclizine; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Strains; Terfenadine; Triazoles

1992
Regulation of hepatic glycogenolysis and vasoconstriction during antigen-induced anaphylaxis.
    The American journal of physiology, 1992, Volume: 262, Issue:5 Pt 1

    Topics: Anaphylaxis; Animals; Antigens; Azepines; Eicosanoids; Epitopes; Female; Glycogen; Liver; Nitric Oxide; Ovalbumin; Platelet Activating Factor; Rats; Rats, Inbred Strains; Triazoles; Vasoconstriction

1992
Platelet activating factor and systemic anaphylaxis in Nippostrongylus brasiliensis-sensitized rats: differential effects of PAF antagonists.
    British journal of pharmacology, 1992, Volume: 106, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Blood Proteins; Diterpenes; Evans Blue; Ginkgolides; Hemodynamics; Lactones; Male; Microspheres; Nippostrongylus; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Triazoles

1992
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:6

    Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; Male; Myocardial Contraction; Ovalbumin; Platelet Activating Factor; Pyrilamine; Triazoles

1990
Beneficial effects of TCV-309, a novel potent and selective platelet activating factor antagonist in endotoxin and anaphylactic shock in rodents.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Furans; Hemolysis; Humans; Hypotension; Isoquinolines; Male; Microsomes; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rabbits; Rats; Rats, Inbred Strains; Shock, Septic; Tetrahydroisoquinolines; Triazoles

1992
A role for phospholipid-derived inflammatory mediators in intestinal anaphylaxis in the rat.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Biological Transport; Carbazoles; Dinoprostone; Electrolytes; Female; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Jejunum; Leukotriene Antagonists; Leukotrienes; Phospholipids; Platelet Activating Factor; Propionates; Quinolines; Rats; Thromboxanes; Triazoles

1992
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
    European journal of pharmacology, 1991, Dec-03, Volume: 205, Issue:3

    Topics: Anaphylaxis; Animals; Azepines; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Male; Mice; Mice, Inbred Strains; Ovalbumin; Platelet Activating Factor; Shock, Septic; Thiazoles; Triazoles

1991
Anaphylactic challenge causes eosinophil accumulation in bronchoalveolar lavage fluid of guinea pigs. Modulation by betamethasone, phenidone, indomethacin, WEB 2086, and a novel antiallergy agent, SCH 37224.
    The American review of respiratory disease, 1990, Volume: 142, Issue:3

    Topics: Albumins; Anaphylaxis; Animals; Asthma; Azepines; Betamethasone; Bronchoalveolar Lavage Fluid; Cell Count; Eosinophils; Guinea Pigs; Histamine; Immunization; Indomethacin; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung; Male; Naphthyridines; Ovalbumin; Platelet Activating Factor; Pyrazoles; Thromboxanes; Triazoles

1990
The booster injection of antigen during active sensitization of guinea-pig modifies the anti-anaphylactic activity of the PAF antagonist WEB 2086.
    British journal of pharmacology, 1990, Volume: 100, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Blood Cell Count; Bronchi; Enzyme-Linked Immunosorbent Assay; Guinea Pigs; Histamine; Immunization, Secondary; Immunoglobulin G; Lung; Ovalbumin; Platelet Activating Factor; Radioimmunoassay; Spectrometry, Fluorescence; Thromboxane B2; Triazoles

1990
Effects of the PAF antagonist WEB 2086 on PAF-induced physiologic alterations and on IgE anaphylaxis in the rabbit.
    The American review of respiratory disease, 1990, Volume: 142, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Bronchial Spasm; Hypotension; Immunoglobulin E; Leukopenia; Lung; Platelet Activating Factor; Rabbits; Thrombocytopenia; Triazoles

1990
Interactions of platelet activating factor, thromboxane A2 and leukotrienes in guinea-pig heart.
    Progress in clinical and biological research, 1989, Volume: 301

    Topics: Anaphylaxis; Animals; Azepines; Cyclooxygenase Inhibitors; Guinea Pigs; Heart; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Naphthoquinones; ortho-Aminobenzoates; Platelet Activating Factor; Thromboxane A2; Triazines; Triazoles

1989
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guinea Pigs; Lung Diseases; Ovalbumin; Platelet Activating Factor; Pyrilamine; Shock, Septic; Triazines; Triazoles

1989
Effect of the PAF-antagonist WEB 2086 on anaphylactic lung reaction: comparison of inhalative and intravenous challenge.
    Agents and actions. Supplements, 1988, Volume: 23

    Topics: Administration, Inhalation; Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Injections, Intravenous; Lung; Platelet Activating Factor; Triazines; Triazoles

1988
Effects of WEB 2086, a novel antagonist of platelet activating factor, in active and passive anaphylaxis.
    Immunopharmacology, 1987, Volume: 13, Issue:2

    Topics: Administration, Oral; Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Immunization; Immunization, Passive; Injections, Intravenous; Male; Mice; Ovalbumin; Platelet Activating Factor; Pyrilamine; Respiration; Triazines; Triazoles

1987
Interference by the novel PAF-acether antagonist WEB 2086 with the bronchopulmonary responses to PAF-acether and to active and passive anaphylactic shock in guinea-pigs.
    European journal of pharmacology, 1987, Aug-21, Volume: 140, Issue:3

    Topics: Anaphylaxis; Animals; Azepines; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indicators and Reagents; Leukopenia; Male; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Radioimmunoassay; Respiratory System; Spectrometry, Fluorescence; Thrombocytopenia; Thromboxane B2; Triazines; Triazoles

1987