Page last updated: 2024-11-05

wb 4101 and Pregnancy

wb 4101 has been researched along with Pregnancy in 9 studies

N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine : A benzodioxine that is 2,3-dihydro-1,4-benzodioxine bearing a [(2',6'-dimethoxyphenoxy)ethylamino]methyl group at position 2. An alpha1A-adrenergic selective antagonist.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" Besides shifting the dose-response curve of 5-HT to the right, 5-MU decreased its maximal effect."1.32Investigation of the role of the serotonergic activity of certain subtype-selective alpha1A antagonists in the relaxant effect on the pregnant rat uterus in vitro. ( Ducza, E; Falkay, G; Gáspár, R; Mihályi, A, 2003)
"Female rats were subjected to stress treatments during pregnancy and the offspring were studied at several different ages."1.27Prenatal stress: effect on development of rat brain adrenergic receptors. ( Peters, DA, 1984)
"The nicotine intake was then maintained at a level of 6."1.27Prenatal nicotine exposure increases adrenergic receptor binding in the rat cerebral cortex. ( Peters, DA, 1984)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bóta, J1
Hajagos-Tóth, J1
Ducza, E2
Samavati, R1
Borsodi, A1
Benyhe, S1
Gáspár, R2
Mihályi, A1
Falkay, G1
Ford, SP1
Reynolds, LP1
Farley, DB1
Bhatnagar, RK1
Van Orden, DE1
Peters, DA2
Hoang, TV1
Choe, EU1
Burgess, RS1
Cork, RC1
Flint, LM1
Ferrara, JJ1
Hu, XQ1
Dyer, DC1
Limon-Boulez, I1
Mhaouty-Kodja, S1
Coudouel, N1
Benoit de Coignac, A1
Legrand, C1
Maltier, JP1
Minneman, KP1
Atkinson, B1

Other Studies

9 other studies available for wb 4101 and Pregnancy

ArticleYear
The effects of female sexual hormones on the expression and function of α1A- and α1D-adrenoceptor subtypes in the late-pregnant rat myometrium.
    European journal of pharmacology, 2015, Dec-15, Volume: 769

    Topics: Animals; Dioxanes; Estradiol; Female; Gene Expression Regulation; Myometrium; Piperazines; Pregnancy

2015
Investigation of the role of the serotonergic activity of certain subtype-selective alpha1A antagonists in the relaxant effect on the pregnant rat uterus in vitro.
    Molecular human reproduction, 2003, Volume: 9, Issue:8

    Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dose-Response Relationship, Drug; Electric Stimulat

2003
Interaction of ovarian steroids and periarterial alpha 1-adrenergic receptors in altering uterine blood flow during the estrous cycle of gilts.
    American journal of obstetrics and gynecology, 1984, Nov-01, Volume: 150, Issue:5 Pt 1

    Topics: Animals; Arteries; Dioxanes; Electric Stimulation; Estradiol; Estrogens; Estrone; Estrus; Female; Fo

1984
Prenatal stress: effect on development of rat brain adrenergic receptors.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:3

    Topics: Age Factors; Analysis of Variance; Animals; Brain; Clonidine; Dihydroalprenolol; Dioxanes; Female; P

1984
Prenatal nicotine exposure increases adrenergic receptor binding in the rat cerebral cortex.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 46, Issue:3

    Topics: Animals; Body Weight; Cerebral Cortex; Clonidine; Dihydroalprenolol; Dioxanes; Female; Neurons; Nico

1984
Characterization of alpha-adrenoceptor activity in the preterm piglet mesentery.
    Journal of pediatric surgery, 1996, Volume: 31, Issue:12

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Azepines; Dioxan

1996
Heterogeneity and complexity of alpha 1-adrenoceptors in the ovine uterine artery and umbilical vein.
    European journal of pharmacology, 1997, Apr-11, Volume: 324, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Binding, Competitive; Ca

1997
The alpha1B-adrenergic receptor subtype activates the phospholipase C signaling pathway in rat myometrium at parturition.
    Biology of reproduction, 1997, Volume: 57, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Membran

1997
Interaction of subtype-selective antagonists with alpha 1-adrenergic receptor-mediated second messenger responses in rat brain.
    Molecular pharmacology, 1991, Volume: 40, Issue:4

    Topics: Adrenergic alpha-Antagonists; Alkylation; Animals; Brain; Calcium Channel Blockers; Cells, Cultured;

1991