wb 4101 has been researched along with Pain in 6 studies
N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine : A benzodioxine that is 2,3-dihydro-1,4-benzodioxine bearing a [(2',6'-dimethoxyphenoxy)ethylamino]methyl group at position 2. An alpha1A-adrenergic selective antagonist.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, M | 2 |
| Wu, Y | 1 |
| Zou, B | 1 |
| Wang, X | 1 |
| Yu, H | 1 |
| Silva, JR | 1 |
| Silva, ML | 1 |
| Prado, WA | 1 |
| Sagen, J | 1 |
| Proudfit, HK | 3 |
| Fang, F | 1 |
| Miller, JF | 1 |
| Hayes, AG | 1 |
| Skingle, M | 1 |
| Tyers, MB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Benefit of Acupuncture Combined to Regional Analgesia for Post Operative Pain Relief After Hysterectomy[NCT06002464] | 72 participants (Anticipated) | Interventional | 2023-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for wb 4101 and Pain
| Article | Year |
|---|---|
Identification of WB4101, an
Topics: Analgesics; Animals; Cells, Cultured; Dioxanes; Disease Models, Animal; Dose-Response Relationship, | 2018 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Antagonists; Analgesia; Anesthetics, Intravenous; Animals; A | 2011 |
Effect of intrathecally administered noradrenergic antagonists on nociception in the rat.
Topics: Animals; Brain Mapping; Brain Stem; Dioxanes; Efferent Pathways; Injections, Spinal; Male; Norepinep | 1984 |
Antinociception produced by microinjection of morphine in the rat periaqueductal gray is enhanced in the foot, but not the tail, by intrathecal injection of alpha1-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Behavior, Animal; Dioxanes; Female; Foot; | 1998 |
Antagonism of stimulation-produced antinociception from ventrolateral pontine sites by intrathecal administration of alpha-adrenergic antagonists and naloxone.
Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Electric Stimulation; Fe | 1990 |
Antagonism of alpha-adrenoceptor agonist-induced antinociception in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Dioxanes; Dioxins; Fem | 1986 |