wb 4101 has been researched along with Heart Disease, Ischemic in 6 studies
N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine : A benzodioxine that is 2,3-dihydro-1,4-benzodioxine bearing a [(2',6'-dimethoxyphenoxy)ethylamino]methyl group at position 2. An alpha1A-adrenergic selective antagonist.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is concluded that automatic arrhythmias induced by alpha 1-adrenergic stimulation during simulated ischemia may be attributed to a specific alpha 1-adrenergic receptor subtype that is blocked by WB-4101." | 1.29 | [The modulation of anomalous automatism in ischemic Purkinje fibers by a specific subclass of alpha 1-adrenoblockers]. ( Aniukhovskiĭ, EP; Rosen, MR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Billman, GE | 1 |
| Aniukhovskiĭ, EP | 2 |
| Rosen, MR | 4 |
| Anyukhovsky, EP | 2 |
| Steinberg, SF | 1 |
| Cohen, IS | 1 |
| Geller, JC | 1 |
| Cua, M | 1 |
| Prieto, L | 1 |
| Guo, SD | 2 |
| Danilo, P | 2 |
| Rozen, MP | 1 |
| Staĭnberg, SF | 1 |
6 other studies available for wb 4101 and Heart Disease, Ischemic
| Article | Year |
|---|---|
Effect of alpha 1-adrenergic receptor antagonists on susceptibility to malignant arrhythmias: protection from ventricular fibrillation.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dioxanes; Disease Models, Animal; Dogs; Elect | 1994 |
[The modulation of anomalous automatism in ischemic Purkinje fibers by a specific subclass of alpha 1-adrenoblockers].
Topics: Action Potentials; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Arrhythmias, Cardiac | 1993 |
Receptor-effector coupling pathway for alpha 1-adrenergic modulation of abnormal automaticity in 'ischemic' canine Purkinje fibers.
Topics: Adrenergic alpha-Antagonists; Animals; Barium; Clonidine; Dioxanes; Dogs; Membrane Potentials; Myoca | 1994 |
Chloroethylclonidine increases the incidence of lethal arrhythmias during coronary occlusion in anesthetized dogs.
Topics: Adrenergic alpha-Antagonists; Animals; Arrhythmias, Cardiac; Clonidine; Dioxanes; Dogs; Female; Male | 1995 |
Responses to norepinephrine of normal and "ischemic" canine Purkinje fibers are consistent with activation of different alpha 1-receptor subtypes.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aminoquinolines; Animals | 1997 |
[Modulation of heart rhythm by alpha-1 adrenoreceptors].
Topics: Animals; Arrhythmias, Cardiac; Clonidine; Dioxanes; Dogs; Electrocardiography; Heart Rate; Myocardia | 1992 |