wb 4101 has been researched along with Disease Models, Animal in 11 studies
N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine : A benzodioxine that is 2,3-dihydro-1,4-benzodioxine bearing a [(2',6'-dimethoxyphenoxy)ethylamino]methyl group at position 2. An alpha1A-adrenergic selective antagonist.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuropathic pain is treated using serotonin norepinephrine reuptake inhibitors with mixed results." | 1.43 | Sex differences in hypothalamic-mediated tonic norepinephrine release for thermal hyperalgesia in rats. ( Banerjee, T; Holden, JE; Jeong, Y; Wagner, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Fujita, S | 1 |
| Yoshida, S | 1 |
| Matsuki, T | 1 |
| Jaiswal, MK | 1 |
| Seki, K | 1 |
| Li, M | 2 |
| Wu, Y | 1 |
| Zou, B | 1 |
| Wang, X | 1 |
| Yu, H | 1 |
| Wagner, M | 1 |
| Banerjee, T | 1 |
| Jeong, Y | 1 |
| Holden, JE | 1 |
| Silva, JR | 1 |
| Silva, ML | 1 |
| Prado, WA | 1 |
| St-John, WM | 1 |
| Leiter, JC | 1 |
| McCaughran, JA | 1 |
| Edwards, E | 1 |
| Schechter, N | 1 |
| Friedman, R | 1 |
| Billman, GE | 1 |
| Jiang, GC | 1 |
| Iwanov, V | 1 |
| Moulds, RF | 1 |
| Luchelli-Fortis, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Benefit of Acupuncture Combined to Regional Analgesia for Post Operative Pain Relief After Hysterectomy[NCT06002464] | 72 participants (Anticipated) | Interventional | 2023-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 other studies available for wb 4101 and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The α1-adrenergic receptors in the amygdala regulate the induction of learned despair through protein kinase C-beta signaling.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Amygdala; Animals; Depressive | 2021 |
Identification of WB4101, an
Topics: Analgesics; Animals; Cells, Cultured; Dioxanes; Disease Models, Animal; Dose-Response Relationship, | 2018 |
Sex differences in hypothalamic-mediated tonic norepinephrine release for thermal hyperalgesia in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Cobalt; Constriction, Pathologic; Dioxanes; Disease Models, A | 2016 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Antagonists; Analgesia; Anesthetics, Intravenous; Animals; A | 2011 |
Maintenance of gasping and restoration of eupnea after hypoxia is impaired following blockers of alpha1-adrenergic receptors and serotonin 5-HT2 receptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Am | 2008 |
Alpha 1- and alpha 2-adrenoceptor binding in the Dahl rat model of hypertension.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Cerebral Cortex; Clonidine; Dioxanes; | 1984 |
Effect of alpha 1-adrenergic receptor antagonists on susceptibility to malignant arrhythmias: protection from ventricular fibrillation.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dioxanes; Disease Models, Animal; Dogs; Elect | 1994 |
Increased sensitivity to inhibition by nifedipine of responses of the mesenteric artery bed of the SHRSP to noradrenaline is not dependent on alpha 1-adrenoceptor subtypes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 1995 |
Rat salivary glands as a model for the study of adrenergic receptor modulation.
Topics: Animals; Autonomic Nervous System; Denervation; Dioxanes; Disease Models, Animal; Prazosin; Rats; Re | 1990 |