warfarin and Vitamin-B-12-Deficiency

Topics: Anemia, Iron-Deficiency; Copper; Folic Acid Deficiency; Hematologic Diseases; Humans; Nutrition Assessment; Nutritional Physiological Phenomena; Vitamin B 12 Deficiency; Vitamin K Deficiency; Warfarin

Cerebral venous thrombosis is relatively rare and characterized by a wide spectrum of clinical features. It is more common in young adults with women affected more than men. The diagnosis of cerebral venous thrombosis is easier nowadays due to easy access to advanced neuroimaging techniques. Abnormalities in thrombophilic profile are associated with enhanced risk of cerebral venous thrombosis. It has varied etiologies such as hypercoagulable states, infection, dehydration, pregnancy, and substance abuse. Hyperhomocysteinemia is found to be closely associated with an enhanced risk of cerebral venous thrombosis.. Here we report a case of cerebral venous thrombosis secondary to hyperhomocysteinemia caused by vitamin B. There are conflicting reports in the literature about the association of hyperhomocysteinemia, B

Topics: Adult; Anticoagulants; Anticonvulsants; Brain; Diuretics, Osmotic; Glycerol; Heparin; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Magnetic Resonance Imaging; Male; Mannitol; Seizures; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Warfarin

Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Atrial Fibrillation; Brain Ischemia; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Stroke; Vitamin B 12; Vitamin B 12 Deficiency; Warfarin

Topics: Anticoagulants; Atrial Fibrillation; Barbiturates; Diagnostic Errors; Drug Interactions; Humans; Medication Errors; Vitamin B 12 Deficiency; Warfarin

Size-frequency distribution curves of erythrocytes were generated with the Coulter Counter in 73 normal subjects and patients. Mean corpuscular volume (MCV) determined by routine calculation and MCV determined by size-frequency distribution were similar in all normal subjects and in patients with a single population of erythrocytes. Some patients with iron-deficiency anemia, folate deficiency, and vitamin B12 deficiency had two discrete erythrocyte populations. Some patients with microcytic anemia were shown to have a population of normocytes in addition to the predominant microcytic population. Reticulocytes and normocytes were identified in two patients recovering from macrocytic anemia. Transfused blood was identified as a separate population in a patient with microcytic anemia. In cases with two erythrocyte populations, the MCV of the principal population, as determined from size-distribution curves, differed from the MCV of the entire erythrocyte pool, as was determined by routine methods. Analysis of sequential erythrocyte size distributions in patients under treatment demonstrated the dynamics of erythrocyte subpopulations. Anisocytosis was quantified and shown to be associated frequently with hospitalized patients.

Topics: Adenocarcinoma; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Pernicious; Brain Diseases; Electronics, Medical; Erythrocyte Count; Erythrocytes; Female; Folic Acid Deficiency; Heart Failure; Hematocrit; Hemorrhage; Humans; Male; Methotrexate; Middle Aged; Reticulocytes; Thrombophlebitis; Vitamin B 12 Deficiency; Warfarin