warfarin has been researched along with Pyelonephritis* in 2 studies
2 other study(ies) available for warfarin and Pyelonephritis
| Article | Year |
|---|---|
Infective endocarditis caused by Enterococcus faecalis treated with continuous infusion of ampicillin without adjunctive aminoglycosides.
Aminoglycosides are useful antimicrobial agents for treating infective endocarditis; however, they occasionally cause troublesome side effects, such as nephrotoxicity and ototoxicity. We herein report a case of infective endocarditis caused by Enterococcus faecalis that was treated successfully with continuous infusion of ampicillin without adjunctive aminoglycosides. The serum ampicillin concentrations were higher than the minimal inhibitory concentration for the target strain. Although the use of ampicillin monotherapy is currently avoided because double β-lactam therapy is reportedly more effective, continuous penicillin administration remains an effective therapeutic choice for treating infective endocarditis. Topics: Aged; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Anticoagulants; Arthroplasty, Replacement, Hip; Atrial Fibrillation; Contraindications; Diagnosis, Differential; Endocarditis, Bacterial; Enterococcus faecalis; Femoral Neck Fractures; Gram-Positive Bacterial Infections; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Mitral Valve; Postoperative Complications; Practice Guidelines as Topic; Pyelonephritis; Streptomycin; Warfarin | 2013 |
Acquired factor V inhibitor in a patient with a mechanical aortic valve under warfarin therapy.
An 84-year-old woman under warfarin therapy, who had undergone mechanical valve replacement 29 months previously, developed coagulation abnormalities after antibiotic treatment for pyelonephritis. Laboratory findings included PT at 47.6 sec, activated thromboplastin time (APTT) at 147 sec, factor V (FV) activity of 4% and FV inhibitor of 8 BU. Although overt bleeding was not observed, administration of prednisolone was started. Her coagulation abnormalities were rapidly normalized. It was later determined that the patient had received bovine thrombin at surgery. The presence of a FV inhibitor should be considered in the differential diagnosis in patients demonstrating an unexpected prolongation of PT under warfarin therapy following surgery. Topics: Aged, 80 and over; Animals; Anti-Bacterial Agents; Anticoagulants; Aortic Valve; Aortic Valve Stenosis; Cattle; Ceftriaxone; Factor V; Female; Heart Valve Prosthesis; Hemorrhagic Disorders; Humans; Immunosuppressive Agents; Partial Thromboplastin Time; Postoperative Complications; Prednisolone; Prothrombin Time; Pyelonephritis; Species Specificity; Thrombin; Warfarin | 2010 |