warfarin and Pleurisy

Herein we report the clinical presentation and radiographic findings of a patient with a known history of multiple nonossifying fibromas, also known as the Jaffe-Campanacci syndrome, who presented with persistent pleuritic chest pain after a fall and was found to have a small pulmonary embolus. The presentation, pathophysiology and management of the syndrome are briefly discussed.

Topics: Angiography; Bone Neoplasms; Cafe-au-Lait Spots; Chest Pain; Female; Fibroma; Heparin; Humans; Pleurisy; Pulmonary Embolism; Syndrome; Treatment Outcome; Warfarin; Young Adult

A 51-year-old man was admitted to our hospital because of dry cough and low grade fever with right-sided pleural fluid and blood eosinophilia. Warfarin had been prescribed following coronary artery bypass grafting. After the discontinuation of warfarin the clinical and chest X-ray findings improved; readministration of the drug caused recurrent blood eosinophilia and pleural effusion in the other lung. Since no other specific etiologies for eosinophilia and pleural effusion were determined by extensive evaluation, warfarin seemed to be associated with his illness. This is the first report of warfarin-induced eosinophilic pleurisy.

Topics: Anticoagulants; Eosinophilia; Humans; Male; Middle Aged; Pleurisy; Warfarin