warfarin and Myositis-Ossificans

warfarin has been researched along with Myositis-Ossificans* in 2 studies

Other Studies

2 other study(ies) available for warfarin and Myositis-Ossificans

Article	Year
Effect of warfarin sodium therapy on excretion of 4-carboxy-L-glutamic acid in scleroderma, dermatomyositis, and myositis ossificans progressiva. Arthritis and rheumatism, 1986, Volume: 29, Issue:3 The effect of warfarin sodium on excretion of calcium, phosphorus, and 4-carboxy-L-glutamic acid (Gla) was studied in 5 patients with ectopic calcification (2 with scleroderma, 1 with dermatomyositis, and 2 with myositis ossificans progressiva). Warfarin reduced urinary excretion of Gla in all patients, but no changes in calcium and phosphorus excretion or in objective parameters of calcinosis were observed during 6-36 months of treatment. Two patients experienced hemorrhagic complications during therapy, emphasizing a hazard of long-term anticoagulation treatment. Since ectopic calcium deposits contain Gla-rich protein, suppression of Gla synthesis by warfarin sodium over a longer period may prevent deposition and allow removal of existing calcinosis deposits. Topics: Adult; Bone and Bones; Calcium; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cyclic AMP; Dermatomyositis; Female; Follow-Up Studies; Glutamates; Hemorrhage; Humans; Male; Middle Aged; Myositis Ossificans; Phosphorus; Radiography; Radionuclide Imaging; Scleroderma, Systemic; Warfarin	1986
Myositis ossificans following porous-ingrowth TK replacement. Orthopaedic review, 1986, Volume: 15, Issue:4 Clinically significant myositis ossificans of the distal thigh following virginal porous-ingrowth total knee arthroplasty has not been previously reported. Associated and potentially contributing factors in this particular case were (1) the patient's preoperative hypertrophic gonarthrosis, (2) our difficulty in regulating her postoperative sodium warfarin (Coumadin) dosages, (3) the postoperative knee manipulation, and (4) possibly, the additional surgical exposure of this patient's distal femur required to use the femur-based alignment instrumentation. Postoperative heterotopic ossification developing in the vicinity of a porous-ingrowth total knee prosthesis can have clinical significance. Treatment of this problem by a means that does not interfere with early bone ingrowth into the implant is a practical concern that warrants investigation. Topics: Aged; Anti-Bacterial Agents; Female; Humans; Knee Prosthesis; Manipulation, Orthopedic; Myositis Ossificans; Postoperative Complications; Radiography; Thigh; Warfarin	1986

Article

Year

Effect of warfarin sodium therapy on excretion of 4-carboxy-L-glutamic acid in scleroderma, dermatomyositis, and myositis ossificans progressiva.

Arthritis and rheumatism, 1986, Volume: 29, Issue:3

The effect of warfarin sodium on excretion of calcium, phosphorus, and 4-carboxy-L-glutamic acid (Gla) was studied in 5 patients with ectopic calcification (2 with scleroderma, 1 with dermatomyositis, and 2 with myositis ossificans progressiva). Warfarin reduced urinary excretion of Gla in all patients, but no changes in calcium and phosphorus excretion or in objective parameters of calcinosis were observed during 6-36 months of treatment. Two patients experienced hemorrhagic complications during therapy, emphasizing a hazard of long-term anticoagulation treatment. Since ectopic calcium deposits contain Gla-rich protein, suppression of Gla synthesis by warfarin sodium over a longer period may prevent deposition and allow removal of existing calcinosis deposits.

Topics: Adult; Bone and Bones; Calcium; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cyclic AMP; Dermatomyositis; Female; Follow-Up Studies; Glutamates; Hemorrhage; Humans; Male; Middle Aged; Myositis Ossificans; Phosphorus; Radiography; Radionuclide Imaging; Scleroderma, Systemic; Warfarin

1986

Myositis ossificans following porous-ingrowth TK replacement.

Orthopaedic review, 1986, Volume: 15, Issue:4

Clinically significant myositis ossificans of the distal thigh following virginal porous-ingrowth total knee arthroplasty has not been previously reported. Associated and potentially contributing factors in this particular case were (1) the patient's preoperative hypertrophic gonarthrosis, (2) our difficulty in regulating her postoperative sodium warfarin (Coumadin) dosages, (3) the postoperative knee manipulation, and (4) possibly, the additional surgical exposure of this patient's distal femur required to use the femur-based alignment instrumentation. Postoperative heterotopic ossification developing in the vicinity of a porous-ingrowth total knee prosthesis can have clinical significance. Treatment of this problem by a means that does not interfere with early bone ingrowth into the implant is a practical concern that warrants investigation.

Topics: Aged; Anti-Bacterial Agents; Female; Humans; Knee Prosthesis; Manipulation, Orthopedic; Myositis Ossificans; Postoperative Complications; Radiography; Thigh; Warfarin

1986