warfarin and Leg-Dermatoses

Topics: Aged; Anticoagulants; Drug Eruptions; Female; Humans; Leg Dermatoses; Necrosis; Obesity; Skin; Warfarin

A 64-year-old woman presented with a hemorrhagic perifollicular rash on her legs while taking warfarin. After biopsy, vitamin C deficiency was suggested as the diagnosis, which ascorbic acid assays later confirmed. Clinical resolution of the rash followed supplementation with vitamin C. Patients on a vitamin K limited diet may also be limiting their intake of vitamin C. Physicians should be aware of this possible correlation, and consider checking vitamin C levels in patients with a perifollicular hemorrhagic rash or other signs of vitamin C deficiency while on warfarin.

Topics: Anticoagulants; Ascorbic Acid; Ascorbic Acid Deficiency; Drug Eruptions; Female; Humans; Leg Dermatoses; Middle Aged; Skin Diseases, Vascular; Warfarin

Topics: Aged; Anticoagulants; Autoantibodies; Chronic Disease; Female; Humans; Leg Dermatoses; Phosphatidylserines; Prothrombin; Skin Diseases, Vascular; Warfarin

Topics: Anticoagulants; Calciphylaxis; Diabetes Mellitus, Type 2; Female; Humans; Leg Dermatoses; Middle Aged; Skin Diseases; Treatment Outcome; Warfarin