warfarin and Foot-Dermatoses

Topics: Aged; Anticoagulants; Body Temperature; Cold Temperature; Foot Dermatoses; Humans; Male; Toes; Warfarin

Skin necrosis is an uncommon complication of warfarin (Coumadin; Dupont Pharma, Wilmington, DE) therapy. The presentation may mimic other disorders. This article reports a case of a 72-year-old woman who presented to the emergency department complaining of swelling and ecchymosis to her left breast and right foot. The patient had been hospitalized for coronary artery bypass grafting, and had been discharged from the hospital earlier that day. This article reviews the pathophysiology and clinical features of warfarin-induced skin necrosis.

Topics: Aged; Anticoagulants; Breast Diseases; Diagnosis, Differential; Emergency Medical Services; Female; Foot Dermatoses; Humans; Necrosis; Skin; Warfarin

"Purple toes" syndrome and a generalized skin eruption developed in a 73-year-old woman who was taking warfarin sodium (Coumadin) as well as antiarrhythmic agents after a stroke. Both the rash and the discoloration of her feet were apparently related to use of warfarin and gradually resolved after discontinuation of the drug.

Topics: Aged; Cerebrovascular Disorders; Female; Foot Dermatoses; Humans; Syndrome; Toes; Warfarin

Topics: Aged; Drug Eruptions; Female; Foot Dermatoses; Humans; Rheumatic Heart Disease; Toes; Warfarin