warfarin and Abscess

Topics: Abdominal Pain; Abscess; Adalimumab; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anticoagulants; Behcet Syndrome; Budd-Chiari Syndrome; Female; Fever; Humans; Liver Abscess; Splenic Diseases; Suction; Tomography, X-Ray Computed; Treatment Outcome; Warfarin; Young Adult

Nervous system infections by Cryptococcus neoformans may occur not only in congenital or acquired immunodeficiency syndromes, but also in immunocompetent hosts. Neurological manifestations of C. neoformans infection include meningitis and, less commonly, parenchymal CNS granulomatous disease. This paper provides detailed clinical descriptions of highly unusual neurological manifestations of cryptococcal nervous system infections. Medical records and diagnostic data including magnetic resonance imaging, histopathology, serology, and CSF analysis were reviewed. A conus medullaris abscess was found in a patient infected with the human immunodeficiency virus (HIV). A patient with Hodgkin's disease was diagnosed with cryptococcal meningitis and dermatitis mimicking ophthalmic zoster. An immunocompetent patient presented with recurrent cerebral infarctions in the setting of cryptococcal meningitis. Cryptococcal infections of the nervous system can cause severe neurological disability when diagnosis is delayed. Sensitive and specific tests are readily available and should be considered when an unusual clinical presentation is encountered.

Topics: Abscess; Adult; Aged; Amphotericin B; Anticoagulants; Antifungal Agents; Brain; Central Nervous System Fungal Infections; Cryptococcosis; Cryptococcus neoformans; HIV Infections; Hodgkin Disease; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Spinal Diseases; Tomography, X-Ray Computed; Warfarin

Topics: Abscess; Adult; Anti-Bacterial Agents; Diagnosis, Differential; Drug Therapy, Combination; Dysuria; Female; Fever of Unknown Origin; Fibrinolytic Agents; Flank Pain; Humans; Kidney Diseases; Renal Veins; Thrombosis; Tomography, X-Ray Computed; Warfarin