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w 7 and Ovarian Neoplasms

w 7 has been researched along with Ovarian Neoplasms in 12 studies

W 7: RN given refers to parent cpd; structure; calmodulin antagonist

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"Effects of N-(6-aminohexyl)-1-naphthalenesulfonamide (W-5) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur, FT) and a mixture of FT and uracil (UFT) were determined in nude mice bearing human ovarian carcinoma (KF cells)."7.67Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas. ( Iwano, I; Kikuchi, Y; Kita, T; Kizawa, I; Kuki, E; Miyauchi, M; Oomori, K, 1989)
"Effects of N-(6-aminohexyl)-1-naphthalenesulfonamide (W-5) and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur, FT) and a mixture of FT and uracil (UFT) were determined in nude mice bearing human ovarian carcinoma (KF cells)."3.67Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas. ( Iwano, I; Kikuchi, Y; Kita, T; Kizawa, I; Kuki, E; Miyauchi, M; Oomori, K, 1989)
"The adjuvant effect of calmodulin antagonists (W-5 and W-7) to 5-fluorouracil (5-FU) was studied by using two human cultured cell lines derived from ovarian adenocarcinoma."3.67Adjuvant effects of calmodulin antagonists to 5-fluorouracil on tumor cell proliferation and the mechanisms. ( Kato, K; Kikuchi, Y; Kizawa, I; Oomori, K, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kikuchi, Y11
Iwano, I7
Kato, K8
Hidaka, H1
Miyauchi, M7
Sasa, H1
Nagata, I2
Kuki, E3
Oomori, K8
Kizawa, I8
Kita, T6
Hirata, J1

Reviews

1 review available for w 7 and Ovarian Neoplasms

ArticleYear
[Pharmacology of calmodulin : calmodulin antagonist (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1981, Volume: 26, Issue:8

    Topics: Animals; Calcium-Binding Proteins; Calmodulin; Cattle; Cricetinae; Diamines; Female; Mice; Neoplasms

1981

Other Studies

11 other studies available for w 7 and Ovarian Neoplasms

ArticleYear
Effects of calmodulin antagonists on human ovarian cancer cell proliferation in vitro.
    Biochemical and biophysical research communications, 1984, Aug-30, Volume: 123, Issue:1

    Topics: Calmodulin; Cell Division; Cell Line; Cisplatin; Cystadenocarcinoma; Doxorubicin; Female; Humans; Ov

1984
Restorative effects of calmodulin antagonists on reduced cisplatin uptake by cisplatin-resistant human ovarian cancer cells.
    Gynecologic oncology, 1990, Volume: 39, Issue:2

    Topics: Biological Transport; Calmodulin; Cisplatin; Cystadenocarcinoma; Drug Resistance; Female; Humans; Ov

1990
Adjuvant effects of calmodulin antagonists on antitumor activity of 1-(2-tetrahydrofuryl)-5-fluorouracil (ftorafur) and a mixture of ftorafur and uracil (UFT) in nude mice bearing human ovarian carcinomas.
    Gynecologic oncology, 1989, Volume: 35, Issue:2

    Topics: Animals; Calmodulin; Carcinoma; Drug Combinations; Drug Synergism; Female; Fluorouracil; Mice; Mice,

1989
[The mechanism of resistance and its circumvention of cisplatin-resistant human ovarian cancer cells].
    Nihon Sanka Fujinka Gakkai zasshi, 1989, Volume: 41, Issue:9

    Topics: Animals; Biological Transport; Calmodulin; Cisplatin; Drug Resistance; Female; Humans; Mice; Mice, N

1989
[Effect of calmodulin antagonists (W-5 and W-7) on antitumor activity of Tegafur and UFT (Tegafur plus uracil)].
    Nihon Sanka Fujinka Gakkai zasshi, 1988, Volume: 40, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Calmodulin; Drug Synergism; Female; Mice; M

1988
Enhancement of antineoplastic effects of cisplatin by a calmodulin antagonist (W-7) in nude mice bearing human ovarian carcinoma.
    Cancer detection and prevention, 1988, Volume: 12, Issue:1-6

    Topics: Animals; Cisplatin; Drug Therapy, Combination; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude

1988
[Potentiation of the antitumor effect of cisplatin by calmodulin antagonists (W-7 and W-5) in nude mice bearing human ovarian carcinoma].
    Nihon Sanka Fujinka Gakkai zasshi, 1988, Volume: 40, Issue:1

    Topics: Animals; Calmodulin; Cisplatin; Drug Synergism; Drug Therapy, Combination; Female; Mice; Mice, Nude;

1988
Establishment of a cisplatin-resistant human ovarian cancer cell line.
    Journal of the National Cancer Institute, 1986, Volume: 77, Issue:6

    Topics: Calmodulin; Cell Division; Cell Line; Cisplatin; Drug Resistance; Female; Humans; Ovarian Neoplasms;

1986
Enhancement of antineoplastic effects of cisplatin by calmodulin antagonists in nude mice bearing human ovarian carcinoma.
    Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1

    Topics: Adenocarcinoma; Animals; Calmodulin; Cisplatin; Cytotoxicity, Immunologic; Drug Administration Sched

1987
Adjuvant effects of calmodulin antagonists to 5-fluorouracil on tumor cell proliferation and the mechanisms.
    Gynecologic oncology, 1987, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Calmodulin; Cell Division; Cell Line; Female; Fluorouracil; Humans; Ovarian Neoplasm

1987
Restorative effects of defective autologous lymphocyte cytotoxicity by calmodulin antagonists.
    Biochemical and biophysical research communications, 1985, Oct-30, Volume: 132, Issue:2

    Topics: Adenocarcinoma; Adult; Animals; Calmodulin; Cell Line; Cystadenocarcinoma; Cytotoxicity, Immunologic

1985