w 7 has been researched along with Niemann-Pick Diseases in 1 studies
W 7: RN given refers to parent cpd; structure; calmodulin antagonist
Niemann-Pick Diseases: A group of autosomal recessive disorders in which harmful quantities of lipids accumulate in the viscera and the central nervous system. They can be caused by deficiencies of enzyme activities (SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and CHOLESTEROL. There are various subtypes based on their clinical and genetic differences.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Masson, M | 1 |
| Spezzatti, B | 1 |
| Chapman, J | 1 |
| Battisti, C | 1 |
| Baumann, N | 1 |
1 other study available for w 7 and Niemann-Pick Diseases
| Article | Year |
|---|---|
Calmodulin antagonists chlorpromazine and W-7 inhibit exogenous cholesterol esterification and sphingomyelinase activity in human skin fibroblast cultures. Similarities between drug-induced and Niemann-Pick type C lipidoses.
Topics: Calmodulin; Chlorpromazine; Cholesterol; Cholesterol Esters; Depression, Chemical; Fibroblasts; Huma | 1992 |