w 7 has been researched along with Depressive Disorder, Major in 1 studies
W 7: RN given refers to parent cpd; structure; calmodulin antagonist
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current pharmacological treatments for major depressive disorder (MDD) are ineffective in a significant proportion of patients, and the identification of new antidepressant compounds has been difficult." | 1.46 | Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning. ( Breen, G; Lee, SH; Murphy, T; Powell, TR; Price, J; Thuret, S, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Powell, TR | 1 |
| Murphy, T | 1 |
| Lee, SH | 1 |
| Price, J | 1 |
| Thuret, S | 1 |
| Breen, G | 1 |
1 other study available for w 7 and Depressive Disorder, Major
| Article | Year |
|---|---|
Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning.
Topics: Antidepressive Agents; Cell Line; Citalopram; Depressive Disorder, Major; Drug Repositioning; Hippoc | 2017 |