w 7 has been researched along with Cardiomegaly in 2 studies
W 7: RN given refers to parent cpd; structure; calmodulin antagonist
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Endothelin-1 (ET-1) induces cardiac hypertrophy." | 3.70 | Ca2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy. ( Aikawa, R; Hayashi, D; Komuro, I; Kudoh, S; Mizukami, M; Nagai, R; Shibasaki, F; Shiojima, I; Toko, H; Yazaki, Y; Zhu, W; Zou, Y, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, W | 1 |
| Zou, Y | 1 |
| Shiojima, I | 1 |
| Kudoh, S | 1 |
| Aikawa, R | 1 |
| Hayashi, D | 1 |
| Mizukami, M | 1 |
| Toko, H | 1 |
| Shibasaki, F | 1 |
| Yazaki, Y | 1 |
| Nagai, R | 1 |
| Komuro, I | 1 |
| Calderone, A | 1 |
| Abdelaziz, N | 1 |
| Colombo, F | 1 |
| Schreiber, KL | 1 |
| Rindt, H | 1 |
2 other studies available for w 7 and Cardiomegaly
| Article | Year |
|---|---|
Ca2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Calcimycin; Calcineurin; C | 2000 |
A farnesyltransferase inhibitor attenuates cardiac myocyte hypertrophy and gene expression.
Topics: Alkyl and Aryl Transferases; Animals; Atrial Natriuretic Factor; Calmodulin; Cardiomegaly; Cells, Cu | 2000 |