Page last updated: 2024-09-05

vx-745 and Inflammation

vx-745 has been researched along with Inflammation in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Balagué, C; Caturla, F; Domínguez, M; Lumeras, W; Maldonado, M; Orellana, A; Segarra, V; Vidal, B; Vidal, L	1
Anderson, WF; Arancio, O; Chico, LW; Minasov, G; Pelletier, JC; Roy, SM; Van Eldik, LJ; Watterson, DM	1
Dastidar, SG; Diwan, M; Najmi, AK; Singh, RK	1

Reviews

1 review(s) available for vx-745 and Inflammation

Article	Year
A Selective and Brain Penetrant p38αMAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction. Journal of medicinal chemistry, 2019, 06-13, Volume: 62, Issue:11 Topics: Animals; Brain; Cognitive Dysfunction; Humans; Inflammation; Nervous System Diseases; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors	2019

Other Studies

2 other study(ies) available for vx-745 and Inflammation

Article	Year
1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase. Journal of medicinal chemistry, 2011, Nov-24, Volume: 54, Issue:22 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Binding Sites; Cell Line; Crystallography, X-Ray; Humans; Inflammation; Lipopolysaccharides; Male; Mice; Microsomes, Liver; Monocytes; Naphthyridines; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Conformation; Rats; Rats, Wistar; Structure-Activity Relationship; Tumor Necrosis Factor-alpha	2011
Differential effect of p38 and MK2 kinase inhibitors on the inflammatory and toxicity biomarkers in vitro. Human & experimental toxicology, 2018, Volume: 37, Issue:5 Topics: Anti-Inflammatory Agents; Biomarkers; Cell Survival; Cells, Cultured; Cytokines; Hep G2 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Inflammation; Intracellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Lipopolysaccharides; MAP Kinase Kinase 4; Naphthalenes; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazoles; Pyridazines; Pyridines; Pyrimidines; THP-1 Cells; U937 Cells	2018

Article

Year

1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase.

Journal of medicinal chemistry, 2011, Nov-24, Volume: 54, Issue:22

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Binding Sites; Cell Line; Crystallography, X-Ray; Humans; Inflammation; Lipopolysaccharides; Male; Mice; Microsomes, Liver; Monocytes; Naphthyridines; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Conformation; Rats; Rats, Wistar; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2011

Differential effect of p38 and MK2 kinase inhibitors on the inflammatory and toxicity biomarkers in vitro.

Human & experimental toxicology, 2018, Volume: 37, Issue:5

Topics: Anti-Inflammatory Agents; Biomarkers; Cell Survival; Cells, Cultured; Cytokines; Hep G2 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Inflammation; Intracellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Lipopolysaccharides; MAP Kinase Kinase 4; Naphthalenes; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazoles; Pyridazines; Pyridines; Pyrimidines; THP-1 Cells; U937 Cells

2018