vx-745 has been researched along with Disease Models, Animal in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Alam, JJ; Germann, U; Krakovsky, M; Levy, A | 1 |
| Alam, JJ | 1 |
| Alvira, E; Anderson, G; Benson, AG; Blevis-Bal, R; Boehm, TL; Bonar, S; Christie, L; Devadas, B; Devraj, RV; Durley, RC; Hepperle, M; Hickory, BS; Hirsch, J; Hitchcock, J; Jerome, KD; Kurumbail, R; Madsen, HM; Marrufo, LD; Messing, D; Monahan, JB; Naing, W; Owen, TJ; Promo, MA; Rucker, PV; Saabye, M; Schindler, JF; Selness, SR; Shieh, H; Walker, JK; Webb, E; Xing, L | 1 |
4 other study(ies) available for vx-745 and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Continuous administration of a p38α inhibitor during the subacute phase after transient ischemia-induced stroke in the rat promotes dose-dependent functional recovery accompanied by increase in brain BDNF protein level.
Topics: Animals; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Ischemia; Male; Mitogen-Activated Protein Kinase 14; p38 Mitogen-Activated Protein Kinases; Pyridazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Recovery of Function; Stroke | 2020 |
Selective Brain-Targeted Antagonism of p38 MAPKα Reduces Hippocampal IL-1β Levels and Improves Morris Water Maze Performance in Aged Rats.
Topics: Aging; Animals; Disease Models, Animal; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Guanylate Kinases; Hippocampus; Humans; Interleukin-1beta; Learning Disabilities; Maze Learning; Membrane Proteins; Mice; Mice, Transgenic; Pyridazines; Pyrimidines; Rats; Reaction Time; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2015 |
Design, synthesis and activity of a potent, selective series of N-aryl pyridinone inhibitors of p38 kinase.
Topics: Animals; Disease Models, Animal; Drug Design; Enzyme Activation; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Male; Microsomes, Liver; Molecular Structure; p38 Mitogen-Activated Protein Kinases; Pyridazines; Pyridones; Pyrimidines; Rats; Rats, Sprague-Dawley | 2011 |