vorinostat has been researched along with von Hippel-Lindau Disease in 1 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
von Hippel-Lindau Disease: An autosomal dominant disorder caused by mutations in a tumor suppressor gene. This syndrome is characterized by abnormal growth of small blood vessels leading to a host of neoplasms. They include HEMANGIOBLASTOMA in the RETINA; CEREBELLUM; and SPINAL CORD; PHEOCHROMOCYTOMA; pancreatic tumors; and renal cell carcinoma (see CARCINOMA, RENAL CELL). Common clinical signs include HYPERTENSION and neurological dysfunctions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vorinostat was tolerated without serious adverse events by all patients." | 1.91 | Proteostasis Modulation in Germline Missense von Hippel Lindau Disease. ( Alvarez, R; Asuzu, DT; Bugarini, A; Chew, EY; Chittiboina, P; Elkahloun, A; Linehan, M; Lonser, RR; Mandal, D; Maric, D; Mastorakos, P; Mullaney, D; Scott, G; Stoica, S; Yang, C; Zhuang, Z, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chittiboina, P | 1 |
| Mandal, D | 1 |
| Bugarini, A | 1 |
| Asuzu, DT | 1 |
| Mullaney, D | 1 |
| Mastorakos, P | 1 |
| Stoica, S | 1 |
| Alvarez, R | 1 |
| Scott, G | 1 |
| Maric, D | 1 |
| Elkahloun, A | 1 |
| Zhuang, Z | 1 |
| Chew, EY | 1 |
| Yang, C | 1 |
| Linehan, M | 1 |
| Lonser, RR | 1 |
1 other study available for vorinostat and von Hippel-Lindau Disease
| Article | Year |
|---|---|
Proteostasis Modulation in Germline Missense von Hippel Lindau Disease.
Topics: Biological Products; Central Nervous System Neoplasms; Hemangioblastoma; Humans; Proteostasis; von H | 2023 |