vorinostat has been researched along with Shock, Septic in 6 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, T | 3 |
| Li, Y | 6 |
| Liu, B | 6 |
| Liu, Z | 3 |
| Chong, W | 4 |
| Duan, X | 1 |
| Deperalta, DK | 1 |
| Velmahos, GC | 4 |
| Alam, HB | 6 |
| Wang, Y | 1 |
| Zhao, H | 1 |
| Sailhamer, EA | 1 |
| Fukudome, EY | 3 |
| Zhang, X | 1 |
| Kheirbek, T | 1 |
| Finkelstein, RA | 3 |
| deMoya, M | 2 |
| Hales, CA | 1 |
| Kochanek, AR | 2 |
| Jin, G | 1 |
| Lu, J | 1 |
| deMoya, MA | 1 |
| Shuja, F | 1 |
| Fukudome, E | 1 |
| Gu, X | 1 |
| Zhao, Y | 1 |
| Zhang, D | 1 |
| Libermann, TA | 1 |
6 other studies available for vorinostat and Shock, Septic
| Article | Year |
|---|---|
Novel pharmacologic treatment attenuates septic shock and improves long-term survival.
Topics: Acute Lung Injury; Animals; Cells, Cultured; Histone Deacetylase Inhibitors; Hydroxamic Acids; Inter | 2013 |
Citrullinated histone H3: a novel target for the treatment of sepsis.
Topics: Animals; Antibodies, Neutralizing; Biomarkers; Citrulline; Disease Models, Animal; Enzyme Inhibitors | 2014 |
Protective effect of suberoylanilide hydroxamic acid against LPS-induced septic shock in rodents.
Topics: Acetylation; Acute Lung Injury; Animals; Blotting, Western; Cell Line, Tumor; Flow Cytometry; Histon | 2009 |
Surviving lethal septic shock without fluid resuscitation in a rodent model.
Topics: Animals; Base Sequence; Cell Line; Disease Models, Animal; DNA Primers; Fluid Therapy; Gene Expressi | 2010 |
Treatment with histone deacetylase inhibitor attenuates MAP kinase mediated liver injury in a lethal model of septic shock.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Hydroxamic Acids; Interleukin-10; Interleukin-6; L | 2010 |
Creating a "pro-survival" phenotype through epigenetic modulation.
Topics: Animals; Base Sequence; C-Reactive Protein; Disease Models, Animal; Epigenomics; Gene Expression; Hy | 2012 |