vorinostat has been researched along with Schistosomiasis in 1 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Schistosomiasis is a major neglected parasitic disease that affects more than 265 million people worldwide and for which the control strategy consists of mass treatment with the only available drug, praziquantel." | 4.02 | Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis. ( Darwish, S; Erdmann, F; Ghazy, E; Heimburg, T; Jung, M; Lancelot, J; Pierce, R; Robaa, D; Romier, C; Schmidt, M; Schmidtkunz, K; Shaik, TB; Simoben, CV; Sippl, W; Truhn, A; Zeyen, P, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghazy, E | 1 |
| Heimburg, T | 1 |
| Lancelot, J | 1 |
| Zeyen, P | 1 |
| Schmidtkunz, K | 1 |
| Truhn, A | 1 |
| Darwish, S | 1 |
| Simoben, CV | 1 |
| Shaik, TB | 1 |
| Erdmann, F | 1 |
| Schmidt, M | 1 |
| Robaa, D | 1 |
| Romier, C | 1 |
| Jung, M | 1 |
| Pierce, R | 1 |
| Sippl, W | 1 |
1 other study available for vorinostat and Schistosomiasis
| Article | Year |
|---|---|
Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasis.
Topics: Animals; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Histone Deacetylase | 2021 |