vorinostat and Sarcoma, Endometrial Stromal
vorinostat has been researched along with Sarcoma, Endometrial Stromal in 1 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Sarcoma, Endometrial Stromal: A highly malignant subset of neoplasms arising from the endometrial stroma. Tumors in this group infiltrate the stroma with a wide range of atypia cells and numerous mitoses. They are capable of widespread metastases (NEOPLASM METASTASIS).
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Endometrial stromal sarcomas are rare and molecular mechanisms involved in their pathogenesis are poorly understood." | 1.35 | SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway. ( Denk, H; Hrzenjak, A; Kremser, ML; Moinfar, F; Strohmeier, B; Zatloukal, K, 2008) |
Research
Studies (1)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Hrzenjak, A | 1 |
Kremser, ML | 1 |
Strohmeier, B | 1 |
Moinfar, F | 1 |
Zatloukal, K | 1 |
Denk, H | 1 |
Other Studies
1 other study available for vorinostat and Sarcoma, Endometrial Stromal
Article | Year |
---|---|
SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway.
Topics: Autophagy; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; | 2008 |