vorinostat has been researched along with Rhabdomyosarcoma in 3 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Rhabdomyosarcoma: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jarząb, A | 1 |
| Łuszczki, JJ | 1 |
| Guz, M | 1 |
| Gumbarewicz, E | 1 |
| Polberg, K | 1 |
| Stepulak, A | 1 |
| Heinicke, U | 1 |
| Fulda, S | 1 |
| Blattmann, C | 1 |
| Oertel, S | 1 |
| Ehemann, V | 1 |
| Thiemann, M | 1 |
| Huber, PE | 1 |
| Bischof, M | 1 |
| Witt, O | 1 |
| Deubzer, HE | 1 |
| Kulozik, AE | 1 |
| Debus, J | 1 |
| Weber, KJ | 1 |
3 other studies available for vorinostat and Rhabdomyosarcoma
| Article | Year |
|---|---|
Additive Interaction of Cisplatin and Histone Deacetylase Inhibitors Combined Treatment in Rhabdomyosarcoma Cells - An Isobolographic Analysis.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; | 2017 |
Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA.
Topics: Acetylation; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell | 2014 |
Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition.
Topics: Antigens, Nuclear; Apoptosis; Carrier Proteins; Cell Cycle; Cell Line, Tumor; Cell Survival; DNA Rep | 2010 |