vorinostat has been researched along with Neuroectodermal Tumors, Primitive in 2 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Neuroectodermal Tumors, Primitive: A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., NEUROECTODERMAL TUMORS, PRIMITIVE, PERIPHERAL). This term is also occasionally used as a synonym for MEDULLOBLASTOMA. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leary, SES | 1 |
| Kilburn, L | 1 |
| Geyer, JR | 1 |
| Kocak, M | 1 |
| Huang, J | 1 |
| Smith, KS | 1 |
| Hadley, J | 1 |
| Ermoian, R | 1 |
| MacDonald, TJ | 1 |
| Goldman, S | 1 |
| Phillips, P | 1 |
| Young Poussaint, T | 1 |
| Olson, JM | 1 |
| Ellison, DW | 1 |
| Dunkel, IJ | 1 |
| Fouladi, M | 1 |
| Onar-Thomas, A | 1 |
| Northcott, PA | 1 |
| Kumar, KS | 1 |
| Sonnemann, J | 1 |
| Beck, JF | 1 |
1 trial available for vorinostat and Neuroectodermal Tumors, Primitive
| Article | Year |
|---|---|
Vorinostat and isotretinoin with chemotherapy in young children with embryonal brain tumors: A report from the Pediatric Brain Tumor Consortium (PBTC-026).
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, | 2022 |
1 other study available for vorinostat and Neuroectodermal Tumors, Primitive
| Article | Year |
|---|---|
Histone deacetylase inhibitors induce cell death in supratentorial primitive neuroectodermal tumor cells.
Topics: Acetylation; Apoptosis; Butyrates; Caspase 3; Caspase 9; DNA Fragmentation; Enzyme Activation; Histo | 2006 |