Page last updated: 2024-11-04

vorinostat and Nasopharyngeal Neoplasms

vorinostat has been researched along with Nasopharyngeal Neoplasms in 5 studies

Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).

Nasopharyngeal Neoplasms: Tumors or cancer of the NASOPHARYNX.

Research Excerpts

ExcerptRelevanceReference
"A novel drug combination of a proteasome inhibitor, bortezomib, and a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), was tested in nasopharyngeal carcinoma (NPC), both in vitro and in vivo."7.79Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus. ( Chiang, AK; Ho, DN; Hui, KF; Lam, BH; Tsao, SW, 2013)
"A novel drug combination of a proteasome inhibitor, bortezomib, and a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), was tested in nasopharyngeal carcinoma (NPC), both in vitro and in vivo."3.79Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus. ( Chiang, AK; Ho, DN; Hui, KF; Lam, BH; Tsao, SW, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hui, KF2
Lam, BH1
Ho, DN2
Tsao, SW1
Chiang, AK2
Lan, MY1
Yang, WL1
Lin, KT1
Lin, JC1
Shann, YJ1
Ho, CY1
Huang, CY1
Schwartz, BE1
Hofer, MD1
Lemieux, ME1
Bauer, DE1
Cameron, MJ1
West, NH1
Agoston, ES1
Reynoird, N1
Khochbin, S1
Ince, TA1
Christie, A1
Janeway, KA1
Vargas, SO1
Perez-Atayde, AR1
Aster, JC1
Sallan, SE1
Kung, AL1
Bradner, JE1
French, CA1
Tsang, CM1
Middeldorp, JM1
Tsao, GS1
Gray, SG1
Qian, CN1
Furge, K1
Guo, X1
Teh, BT1

Other Studies

5 other studies available for vorinostat and Nasopharyngeal Neoplasms

ArticleYear
Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus.
    Molecular cancer therapeutics, 2013, Volume: 12, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Carcinoma; Caspases; Cell Line

2013
Using computational strategies to predict potential drugs for nasopharyngeal carcinoma.
    Head & neck, 2014, Volume: 36, Issue:10

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Gene Expression Regulatio

2014
Differentiation of NUT midline carcinoma by epigenomic reprogramming.
    Cancer research, 2011, Apr-01, Volume: 71, Issue:7

    Topics: Acetylation; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Child; Female; Gene Knockdown

2011
Activation of lytic cycle of Epstein-Barr virus by suberoylanilide hydroxamic acid leads to apoptosis and tumor growth suppression of nasopharyngeal carcinoma.
    International journal of cancer, 2012, Oct-15, Volume: 131, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma; Cell Proliferation; Epstein

2012
Microarray profiling of the effects of histone deacetylase inhibitors on gene expression in cancer cell lines.
    International journal of oncology, 2004, Volume: 24, Issue:4

    Topics: Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Enzyme Inhibitors; Gene Expression Profiling; Gene

2004