vorinostat has been researched along with Malaria in 5 studies
Vorinostat: A hydroxamic acid and anilide derivative that acts as a HISTONE DEACETYLASE inhibitor. It is used in the treatment of CUTANEOUS T-CELL LYMPHOMA and SEZARY SYNDROME.
vorinostat : A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dow, GS | 1 |
| Chen, Y | 1 |
| Andrews, KT | 2 |
| Caridha, D | 1 |
| Gerena, L | 1 |
| Gettayacamin, M | 1 |
| Johnson, J | 1 |
| Li, Q | 1 |
| Melendez, V | 1 |
| Obaldia, N | 1 |
| Tran, TN | 1 |
| Kozikowski, AP | 1 |
| Agbor-Enoh, S | 1 |
| Seudieu, C | 1 |
| Davidson, E | 1 |
| Dritschilo, A | 1 |
| Jung, M | 1 |
| Patil, V | 1 |
| Guerrant, W | 1 |
| Chen, PC | 1 |
| Gryder, B | 1 |
| Benicewicz, DB | 1 |
| Khan, SI | 1 |
| Tekwani, BL | 1 |
| Oyelere, AK | 1 |
| Giannini, G | 1 |
| Battistuzzi, G | 1 |
| Vignola, D | 1 |
| Chua, MJ | 1 |
| Arnold, MS | 1 |
| Xu, W | 1 |
| Lancelot, J | 1 |
| Lamotte, S | 1 |
| Späth, GF | 1 |
| Prina, E | 1 |
| Pierce, RJ | 1 |
| Fairlie, DP | 1 |
| Skinner-Adams, TS | 1 |
5 other studies available for vorinostat and Malaria
| Article | Year |
|---|---|
Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors.
Topics: Animals; Antimalarials; Aotidae; Drug Resistance; Enzyme Inhibitors; Histone Deacetylase Inhibitors; | 2008 |
Novel inhibitor of Plasmodium histone deacetylase that cures P. berghei-infected mice.
Topics: Animals; Antimalarials; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Malar | 2009 |
Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.
Topics: Antimalarials; Antiprotozoal Agents; Histone Deacetylase Inhibitors; Histone Deacetylases; Leishmani | 2010 |
Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite.
Topics: Animals; Antimalarials; Cell Line, Tumor; Dipeptides; Disease Models, Animal; Histone Deacetylase In | 2015 |
Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.
Topics: Acetylation; Administration, Oral; Animals; Depsipeptides; HEK293 Cells; Histone Deacetylase Inhibit | 2017 |